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NCT04651296 · ClinicalTrials.gov registry record · Phase 2
Compassion Meditation vs. Health Education for Veterans
A Phase 2 study of Depression and Chronic Pain, sponsored by VA Office of Research and Development.
- Active
- Registry status
- Phase 2
- Development phase
- 142
- Enrollment target
- 1
- Study location
NCT04651296: Active Phase 2 study of Depression and Chronic Pain, sponsored by VA Office of Research and Development.
NCT04651296 is a Phase 2 study of Depression and Chronic Pain that is active but no longer recruiting, run by VA Office of Research and Development. The registered enrollment target is 142 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04651296, a Phase 2 study of Depression and Chronic Pain, is active but no longer recruiting, sponsored by VA Office of Research and Development.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 142 participants
- Enrollment target
- 1
- Study location
Study Summary
Chronic pain (CP) is a major health problem for military Veterans, and CP is often associated with comorbid mental health problems, including posttraumatic stress disorder (PTSD) and depression. CP with psychological comorbidity is associated with increased healthcare costs, medication use, risk of suicide and rates of disability and reduced quality of life. Current empirically supported treatments do not always lead to substantial improvements (up to 50% of patients drop out or are do not respond to treatment). This project was designed to evaluate the efficacy of a novel intervention for addressing these challenges. Compassion meditation (CM), a meditative practice that focuses on the wish to remove suffering, is a contemplative practice that has promise for the amelioration of physical and mental health problems as well as promoting positive affect and improving quality of life. This study will evaluate the efficacy of Cognitively-Based Compassion Training for Chronic Pain with Psychological Comorbidity (CBCT-CP+) compared to Health Education while Living with Pain (H.E.L.P.) control condition, in a sample of among Veterans with CP conditions and psychological comorbidity.
Primary Outcome
Self-report questionnaire; pain interference subscale includes 7 items measuring the degree to which pain interferes with various aspects of life, including mobility, social activities, and mood. Subscale scores range from 0 to 70 with higher scores indicative of greater pain disability.
Conditions Studied
Interventions
- BEHAVIORAL compassion meditation
- BEHAVIORAL health education
Study Locations (1)
California
- VA San Diego Healthcare System, San Diego, CA - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 142 participants |
| Start Date | 2022-01-04 |
| Est. Completion | 2026-02-28 |
| Phase | Phase 2 |
What the registry record for NCT04651296 still lists
NCT04651296 is an interventional study that assigns participants to a tested intervention. The registered 142 participants enrollment target is mid-sized for trials with a published cap, below the 786-participant average among 679 other Depression trials with a reported enrollment target (82% lower).
The record links to 3 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which compassion meditation is the first listed.
NCT04651296 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04651296 about?
NCT04651296 is a clinical study titled "Compassion Meditation vs. Health Education for Veterans". Chronic pain (CP) is a major health problem for military Veterans, and CP is often associated with comorbid mental health problems, including posttraumatic stress disorder (PTSD) and depression. CP with psychological comorbidity is associated with increased healthcare costs, medication use, risk of ...
What is the current status of trial NCT04651296?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 142 participants. The study started on 2022-01-04. Estimated completion is 2026-02-28.
What conditions does trial NCT04651296 study?
This clinical trial studies the following conditions: Depression, Chronic Pain, Stress Disorders, Post-Traumatic.
What interventions are being tested in trial NCT04651296?
The interventions under investigation include: compassion meditation (BEHAVIORAL), health education (BEHAVIORAL).
Who is sponsoring clinical trial NCT04651296?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04651296 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04651296's enrollment target sits among peer trials
142 269th of 679 higher than 411 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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