Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05517304 · ClinicalTrials.gov registry record · NA
Transcutaneous Vagal Nerve Stimulation in Veterans With Posttraumatic Stress Disorder
A NA study of Stress Disorders, Post-Traumatic, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT05517304: Recruiting NA study of Stress Disorders, Post-Traumatic, sponsored by VA Office of Research and Development.
NCT05517304 is a NA study of Stress Disorders, Post-Traumatic that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 80 participants, below the 155-participant average among 66 other Stress Disorders, Post-Traumatic trials with a reported enrollment target (48% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05517304, a NA study of Stress Disorders, Post-Traumatic, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
This study effects the effects of transcutaneous cervical vagal nerve stimulation (tcVNS) or a sham control on brain, physiology, and PTSD symptoms in Veterans with posttraumatic stress disorder (PTSD). Veterans undergo brain imaging and physiological measures in conjunction with traumatic scripts before and after three months of twice daily treatment with tcVNS or sham stimulation at home.
Primary Outcome
Change in PTSD symptoms measured with the Clinician Administered PTSD Scale (CAPS) and PTSD Checklist (PCL) in tcVNS versus sham conditions
Conditions Studied
Interventions
- DEVICE Sham
- DEVICE tcVNS
Study Locations (1)
Georgia
- Atlanta VA Medical and Rehab Center, Decatur, GA - Decatur
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2022-10-01 |
| Est. Completion | 2027-11-10 |
| Phase | NA |
What NCT05517304 shows while recruiting
NCT05517304 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 155-participant average among 66 other Stress Disorders, Post-Traumatic trials with a reported enrollment target (48% lower).
The record links to 1 condition, with Stress Disorders, Post-Traumatic appearing as the primary indexed condition, and to 2 interventions - of which Sham is the first listed.
NCT05517304 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT05517304 about?
NCT05517304 is a clinical study titled "Transcutaneous Vagal Nerve Stimulation in Veterans With Posttraumatic Stress Disorder". This study effects the effects of transcutaneous cervical vagal nerve stimulation (tcVNS) or a sham control on brain, physiology, and PTSD symptoms in Veterans with posttraumatic stress disorder (PTSD). Veterans undergo brain imaging and physiological measures in conjunction with traumatic scripts b...
What is the current status of trial NCT05517304?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2022-10-01. Estimated completion is 2027-11-10.
What conditions does trial NCT05517304 study?
This clinical trial studies the following conditions: Stress Disorders, Post-Traumatic.
What interventions are being tested in trial NCT05517304?
The interventions under investigation include: Sham (DEVICE), tcVNS (DEVICE).
Who is sponsoring clinical trial NCT05517304?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05517304 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stress Disorders, Post-Traumatic
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05517304's enrollment target sits among peer trials
80 36th of 66 higher than 29 of 66 other Stress Disorders, Post-Traumatic trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stress Disorders, Post-Traumatic trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Manage Emotions to Reduce Aggression (MERA)
RECRUITING · NA
-
SMART Therapist Training: A Hybrid Factorial-SMART Design
RECRUITING · NA
-
Postpartum Care in the NICU (PeliCaN) Transitions
RECRUITING · NA
-
Healthy Recovery After Trauma Study
RECRUITING · NA
-
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
RECRUITING · NA
-
Whole Health in VA Mental Health: Omnis Salutis
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01243931 · 80 participants · NA
Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy
- NCT01659203 · 80 participants · Phase 1
Proton or Photon RT for Retroperitoneal Sarcomas
- NCT01803451 · 80 participants · Early Phase 1
Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass
- NCT01964859 · 80 participants · Phase 2
Feasibility Study for Fibroblast Autologous Skin Grafts
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI