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NCT05220137 · ClinicalTrials.gov registry record · NA
Using the Multiphase Optimization Strategy to Adapt Cognitive Processing Therapy
A NA study of Stress Disorders, Post-Traumatic, sponsored by VA Office of Research and Development.
- Active
- Registry status
- NA
- Development phase
- 270
- Enrollment target
- 3
- Study locations
NCT05220137 is a NA study of Stress Disorders, Post-Traumatic that is active but no longer recruiting, run by VA Office of Research and Development. The registered enrollment target is 270 participants, above the 152-participant average among 64 other Stress Disorders, Post-Traumatic trials with a reported enrollment target (78% higher). The trial reports 3 study locations across 3 states.
The verdict
NCT05220137, a NA study of Stress Disorders, Post-Traumatic, is active but no longer recruiting, sponsored by VA Office of Research and Development.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 270 participants
- Enrollment target
- 3
- Study locations
Study Summary
Cognitive Processing Therapy (CPT) consists of discrete therapeutic components that are delivered across 12 sessions, but most Veterans never reach session 12, and those who drop out receive only 4 sessions on average. Veterans drop out because of time constraints, logistics, and lack of perceived benefit. Unfortunately, Veterans who drop out prematurely may never receive the most effective components of CPT and continue to experience symptom-related distress and numerous other negative outcomes, including lost productivity, substance use, later-life physical disability, reduced quality of life, and increased risk of suicide. The overall objective of this study is to adapt CPT into a brief, effective format. The rationale is that identifying the most effective intervention components and delivering only those components will make CPT deliverable in a shorter timeframe, thus improving efficiency, reducing drop-out related to poor treatment response, and ensuring that Veterans receive the most beneficial components of treatment, which will significantly improve their quality of life.
Conditions Studied
Interventions
- BEHAVIORAL Modified A-B-C: Working with Events, Thoughts, and Feelings
- BEHAVIORAL Challenging Questions
- BEHAVIORAL Patterns of Problematic Thinking
- BEHAVIORAL Challenging Beliefs
- BEHAVIORAL Veteran's choice of Module (Safety/Trust/Power and Control/Esteem/Intimacy)
Study Locations (3)
Michigan
- VA Ann Arbor Healthcare System, Ann Arbor, MI - Ann Arbor
Ohio
- Cincinnati VA Medical Center, Cincinnati, OH - Cincinnati
Utah
- VA Salt Lake City Health Care System, Salt Lake City, UT - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 270 participants |
| Start Date | 2022-08-01 |
| Est. Completion | 2026-03-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05220137
The ClinicalTrials.gov registry entry for NCT05220137 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 270 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 152-participant average among 64 other Stress Disorders, Post-Traumatic trials with a reported enrollment target (78% higher). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Stress Disorders, Post-Traumatic appearing as the primary indexed condition, and to 5 interventions - of which Modified A-B-C: Working with Events, Thoughts, and Feelings is the first listed.
NCT05220137 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Michigan, Ohio, Utah.
Frequently Asked Questions
What is clinical trial NCT05220137 about?
NCT05220137 is a clinical study titled "Using the Multiphase Optimization Strategy to Adapt Cognitive Processing Therapy". Cognitive Processing Therapy (CPT) consists of discrete therapeutic components that are delivered across 12 sessions, but most Veterans never reach session 12, and those who drop out receive only 4 sessions on average. Veterans drop out because of time constraints, logistics, and lack of perceived b...
What is the current status of trial NCT05220137?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 270 participants. The study started on 2022-08-01. Estimated completion is 2026-03-31.
What conditions does trial NCT05220137 study?
This clinical trial studies the following conditions: Stress Disorders, Post-Traumatic.
What interventions are being tested in trial NCT05220137?
The interventions under investigation include: Modified A-B-C: Working with Events, Thoughts, and Feelings (BEHAVIORAL), Challenging Questions (BEHAVIORAL), Patterns of Problematic Thinking (BEHAVIORAL), Challenging Beliefs (BEHAVIORAL), Veteran's choice of Module (Safety/Trust/Power and Control/Esteem/Intimacy) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05220137?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05220137 being conducted?
This trial has 3 study locations across Michigan, Ohio, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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