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NCT06296186 · ClinicalTrials.gov registry record · NA
Massed Prolonged Exposure for PTSD in Substance Use Treatment
A NA study of Substance Use Disorders and Stress Disorders, Post-Traumatic, sponsored by Veterans Medical Research Foundation.
- Recruiting
- Registry status
- NA
- Development phase
- 200
- Enrollment target
- 4
- Study locations
NCT06296186: Recruiting NA study of Substance Use Disorders and Stress Disorders, Post-Traumatic, sponsored by Veterans Medical Research Foundation.
NCT06296186 is a NA study of Substance Use Disorders and Stress Disorders, Post-Traumatic that is actively recruiting participants, run by Veterans Medical Research Foundation. The registered enrollment target is 200 participants, below the 498-participant average among 93 other Substance Use Disorders trials with a reported enrollment target (60% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06296186, a NA study of Substance Use Disorders and Stress Disorders, Post-Traumatic, is actively recruiting participants, sponsored by Veterans Medical Research Foundation.
- RECRUITING
- Registry status
- NA
- Development phase
- 200 participants
- Enrollment target
- 4
- Study locations
Study Summary
The goal of this clinical trial is to learn if receiving Prolonged Exposure Therapy for PTSD in massed format (multiple sessions weekly) is as effective as receiving it with sessions once per week among veterans with PTSD and substance use disorder in intensive outpatient substance use treatment. The main questions it aims to answer are: * Will the massed format help participants complete and benefit from Prolonged Exposure in terms of PTSD symptoms? * Will it help participants reduce substance use? Participants who are in intensive substance use treatment will be asked to complete Prolonged Exposure with either weekly sessions or multiple sessions per week.
Primary Outcome
Measures PTSD symptom severity, score range 0-80, higher scores mean greater symptom severity
Conditions Studied
Interventions
- BEHAVIORAL Prolonged Exposure Therapy
Study Locations (4)
California
- VA San Diego Healthcare System - San Diego
Florida
- VA Tampa Healthcare System - Tampa
Georgia
- VA Atlanta Healthcare System - Atlanta
Illinois
- Hines VA Healthcare System - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2024-09-01 |
| Est. Completion | 2027-08 |
| Phase | NA |
What NCT06296186 shows while recruiting
NCT06296186 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 498-participant average among 93 other Substance Use Disorders trials with a reported enrollment target (60% lower).
The record links to 2 conditions, with Substance Use Disorders appearing as the primary indexed condition, and to 1 intervention - of which Prolonged Exposure Therapy is the first listed.
NCT06296186 reports a single indexed study location in California, Florida, Georgia.
Frequently Asked Questions
What is clinical trial NCT06296186 about?
NCT06296186 is a clinical study titled "Massed Prolonged Exposure for PTSD in Substance Use Treatment". The goal of this clinical trial is to learn if receiving Prolonged Exposure Therapy for PTSD in massed format (multiple sessions weekly) is as effective as receiving it with sessions once per week among veterans with PTSD and substance use disorder in intensive outpatient substance use treatment. Th...
What is the current status of trial NCT06296186?
This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2024-09-01. Estimated completion is 2027-08.
What conditions does trial NCT06296186 study?
This clinical trial studies the following conditions: Substance Use Disorders, Stress Disorders, Post-Traumatic.
What interventions are being tested in trial NCT06296186?
The interventions under investigation include: Prolonged Exposure Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT06296186?
This trial is sponsored by Veterans Medical Research Foundation, which has 35 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06296186 being conducted?
This trial has 4 study locations across California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Substance Use Disorders
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06296186's enrollment target sits among peer trials
200 34th of 93 higher than 59 of 93 other Substance Use Disorders trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Substance Use Disorders trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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