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RECRUITING NA

Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure

NCT06296589 · View on ClinicalTrials.gov ↗

Study Summary

The goal of this clinical trial is to learn if receiving Trauma-Informed Guilt Reduction (TrIGR) Therapy is as effective as receiving Prolonged Exposure Therapy among veterans with PTSD and trauma related guilt. The main questions it aims to answer are: Will TrIGR be comparable to PE in terms of PTSD symptom reduction? Will it TrIGR be comparable to PE in improving functioning and reducing depression symptoms? Will it be superior in improving trauma-related guilt and shame?

Interventions

  • BEHAVIORAL Prolonged Exposure Therapy
  • BEHAVIORAL Trauma Informed Guilt Reduction Therapy

Study Locations (3)

Arkansas

  • Little Rock Veterans Health Care System (LRVHCS) — Little Rock

Louisiana

  • Southeast Louisiana Veterans Health Care System (SLVHCS) — New Orleans

Wisconsin

  • William S. Middleton Memorial Hospital — Madison

Trial Details

FieldValue
Enrollment Target 158 participants
Start Date 2024-12-01
Est. Completion 2027-08
Phase NA

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06296589

The ClinicalTrials.gov registry entry for NCT06296589 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 158 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Veterans Medical Research Foundation, which has 17 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Stress Disorders, Post-Traumatic appearing as the primary indexed condition, and to 2 interventions — of which Prolonged Exposure Therapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06296589 reports 3 study locations spanning 3 distinct geographic areas — top geographies include Arkansas, Louisiana, Wisconsin. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06296589 about?

NCT06296589 is a clinical study titled "Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure". The goal of this clinical trial is to learn if receiving Trauma-Informed Guilt Reduction (TrIGR) Therapy is as effective as receiving Prolonged Exposure Therapy among veterans with PTSD and trauma related guilt. The main questions it aims to answer are: Will TrIGR be comparable to PE in terms of PT...

What is the current status of trial NCT06296589?

This trial is currently recruiting. It is a NA study. The enrollment target is 158 participants. The study started on 2024-12-01. Estimated completion is 2027-08.

What conditions does trial NCT06296589 study?

This clinical trial studies the following conditions: Stress Disorders, Post-Traumatic. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06296589?

The interventions under investigation include: Prolonged Exposure Therapy (BEHAVIORAL), Trauma Informed Guilt Reduction Therapy (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06296589?

This trial is sponsored by Veterans Medical Research Foundation, which has 17 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06296589 being conducted?

This trial has 3 study locations across Arkansas, Louisiana, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial