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NCT04180930 · ClinicalTrials.gov registry record

An Evaluation of Two PTSD Assessments in an Active Duty and Military Veteran Sample

A clinical trial of Stress Disorders, Post-Traumatic, sponsored by U.S. Army Medical Research and Development Command.

Recruiting
Registry status
950
Enrollment target
3
Study locations

NCT04180930: Recruiting study of Stress Disorders, Post-Traumatic, sponsored by U.S. Army Medical Research and Development Command.

NCT04180930 is a study of Stress Disorders, Post-Traumatic that is actively recruiting participants, run by U.S. Army Medical Research and Development Command. The registered enrollment target is 950 participants, above the 142-participant average among 66 other Stress Disorders, Post-Traumatic trials with a reported enrollment target (569% higher). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04180930, a study of Stress Disorders, Post-Traumatic, is actively recruiting participants, sponsored by U.S. Army Medical Research and Development Command.

RECRUITING
Registry status
950 participants
Enrollment target
3
Study locations

Study Summary

Given the high prevalence of post-traumatic stress disorder (PTSD) in veterans and active duty military, the focus of this research study is to test the reliability of two new PTSD assessments, the Clinician Administered PTSD Scale for DSM-5 (CAPS-5) and the PTSD Symptom Scale Interview for DSM-5 (PSSI-5) and compare the results between the two new assessments and the previous "gold standard", the Clinician Administered PTSD Scale for DSM-IV (CAPS-IV). Biomarkers believed to be related to PTSD (e.g., biofluid biomarkers, cognitive and physiological markers, and neural activity as measured by EEG) will be collected to inform targeted interventions in specific groups of patients and other large-scale biomarker discovery efforts in the field. Participants will be 950 male and female active duty military and veterans ages 18 or older who have been exposed to at least one traumatic event.

Primary Outcome

Concordance of the Clinician Administered PTSD Scale Total Score of at 2 visits. The severity of diagnosed PTSD is determined by the total score. (minimum score of 0 = absent to a maximum score of 80 = extreme)

Conditions Studied

Stress Disorders, Post-Traumatic

Interventions

  • DIAGNOSTIC_TEST CAPS-5
  • DIAGNOSTIC_TEST PSSI-5
  • DIAGNOSTIC_TEST CAPS-IV

Study Locations (3)

Hawaii

  • Tripler Army Medical Center - Honolulu

Kentucky

  • Cincinnati VA Medical Center - Trauma Recovery Center - Fort Thomas

Maryland

  • Walter Reed National Military Medical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 950 participants
Start Date 2019-04-15
Est. Completion 2025-06-30
U.S. Army Medical Research and Development Command

77 total trials

What NCT04180930 shows while recruiting

NCT04180930 is an observational study that tracks outcomes without assigning an intervention. The registered 950 participants enrollment target is mid-sized for trials with a published cap, above the 142-participant average among 66 other Stress Disorders, Post-Traumatic trials with a reported enrollment target (569% higher).

The record links to 1 condition, with Stress Disorders, Post-Traumatic appearing as the primary indexed condition, and to 3 interventions - of which CAPS-5 is the first listed.

NCT04180930 reports a single indexed study location in Hawaii, Kentucky, Maryland.

Frequently Asked Questions

What is clinical trial NCT04180930 about?

NCT04180930 is a clinical study titled "An Evaluation of Two PTSD Assessments in an Active Duty and Military Veteran Sample". Given the high prevalence of post-traumatic stress disorder (PTSD) in veterans and active duty military, the focus of this research study is to test the reliability of two new PTSD assessments, the Clinician Administered PTSD Scale for DSM-5 (CAPS-5) and the PTSD Symptom Scale Interview for DSM-5 (P...

What is the current status of trial NCT04180930?

This trial is currently recruiting. The enrollment target is 950 participants. The study started on 2019-04-15. Estimated completion is 2025-06-30.

What conditions does trial NCT04180930 study?

This clinical trial studies the following conditions: Stress Disorders, Post-Traumatic.

What interventions are being tested in trial NCT04180930?

The interventions under investigation include: CAPS-5 (DIAGNOSTIC_TEST), PSSI-5 (DIAGNOSTIC_TEST), CAPS-IV (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT04180930?

This trial is sponsored by U.S. Army Medical Research and Development Command, which has 77 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04180930 being conducted?

This trial has 3 study locations across Hawaii, Kentucky, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Stress Disorders, Post-Traumatic

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04180930's enrollment target sits among peer trials

950 1st of 66 higher than 66 of 66 other Stress Disorders, Post-Traumatic trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Stress Disorders, Post-Traumatic trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT04180930

Source: ClinicalTrials.gov NCT04180930, the US trial registry maintained by the National Library of Medicine. NCT04180930 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.