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Diabetic Foot Ulcer: full-pipeline trial registry
42 of 68 indexed Diabetic Foot Ulcer trials are currently recruiting.
Corpus placement: #203 of 28,707 conditions by registered trial count.
68 US clinical trials · 42 currently recruiting · #203 of 28,707 conditions by registered trial count
Diabetic Foot Ulcer: 68 US clinical trials tracked, 42 recruiting.
Diabetic Foot Ulcer is the subject of 68 registered US clinical trials on ClinicalTrials.gov, 42 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Applied Biologics, running 3 of these trials.
Enrollment posture brief
Registry condition diabetic-foot-ulcer
OPEN 42 | RECR 62% | LATE 9 | EARLY 8 | RANK #203 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Pregnancy, High Risk (62% recruiting · 21 trials)
Diabetic Foot Ulcer lists 42 open slots (62% of 68 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Diabetic Foot Ulcer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Diabetic Foot Ulcer is recruiting above its size-band peers.
42 of 68 indexed trials (61.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Diabetic Foot Ulcer trials is spread across many organizations.
Applied Biologics accounts for 3 of 68 trials (4.4%). 52 distinct sponsors appear on at least one study for this condition label.
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Typical Diabetic Foot Ulcer enrolment sits around 120 participants.
Median target enrolment is 120 among the 68 trials that report a genuine target (sentinel values excluded). 28 of those (41.2%) plan for fewer than 100 participants.
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Diabetic Foot Ulcer research is mostly interventional.
61 interventional and 7 observational studies make up this index (89.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
68 total, page 1 of 2
DFC 004 Biomarkers for Active Diabetic Foot Ulcers
University of Michigan
NCT06104969
Non-Invasive Testing to Evaluate Wound Healing in Diabetes
University of Texas Southwestern Medical Center
NCT04232631
Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers
BioLab Holdings
NCT07089602
Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers
Piomic Medical
NCT05758545
Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy
Sequence LifeScience
NCT07086443
A Modified Platform Trial of Multiple CAMPs for the Management of Diabetic Foot Ulcers and Venous Leg Ulcers
Integra LifeSciences Corporation
NCT06453187
Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.
Tiger Biosciences
NCT06826339
Modified Multi-Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of DFU and VLUs
Stability Biologics
NCT06560502
EDX110 Randomized Control Trial for Treatment of DFUs
ConvaTec
NCT07209358
Comprehensive Assistance and Resources for Effective Diabetic Foot Navigation
Emory University
NCT07223268
Clinical Utility of an Amniotic Membrane Allograft for Diabetic Foot Ulcer Wound Management
Legacy Medical Consultants
NCT06420245
A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer
Energenesis Biomedical Co.
NCT05930210
Smart Boot Use to Measure Offloading Adherence
University of Southern California
NCT04460573
Study Assessing Complete Wound Healing by Comparing Surgenex® PelloGraft in Treating DFU and SanoGraft® in Treating VLU to SOC
Surgenex
NCT06515093
Real World Evidence with the Debritom+ TM Novel Micro Water Jet Technology At a Single Wound Center
Medaxis
NCT04920253
Orthotic Treatment of Diabetic Foot Ulcers
VA Office of Research and Development
NCT05094037
Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs
MiMedx Group
NCT06600724
Evaluating the Efficacy of Perinatal Membrane Allografts in Addition to the Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers.
Samaritan Biologics
NCT06437028
A Study to Evaluate the Efficacy of a Purified Native Type 1 Collagen Extracellular Matrix With Polyhexamethylene Biguanide Antimicrobial (PCMP) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers
Organogenesis
NCT06618612
Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone
Capsicure
NCT06455475
Amnio-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone
Capsicure
NCT06572839
Evaluating the Efficacy NeoThelium FT in the Treatment of Diabetic Foot Ulcers
NuScience Medical Biologics
NCT06938685
Evaluating the Efficacy of OCM™ (Omeza® Complete Matrix) in the Treatment of Diabetic Foot Ulcers
Omeza
NCT07161830
Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care Versus Standard of Care
Applied Biologics
NCT06564831
Feasibility and Effectiveness of a Remote Monitoring Program for the Treatment of Diabetic Foot Ulcers
Johns Hopkins University
NCT05579743
Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)
Cellution Biologics
NCT07014176
Total Contact Soft Cast in Diabetic Foot Ulcers
University of Minnesota
NCT04210089
Dehydrated Human Amnion Membrane and Standard of Care Versus Standard of Care Alone in Nonhealing Diabetic Foot Ulcers
Axolotl Biologix
NCT06550596
Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Gait Correction in Reducing Diabetic Foot Ulceration Or Subsequent Amputation in Patients With a History of a Diabetic Foot Ulceration
Johns Hopkins University
NCT04164641
A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.
Molnlycke Health Care AB
NCT05588583
A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers
Applied Biologics
NCT07159282
Exercise Enhances Wound Healing in Patients With Diabetic Foot Ulcers
University of New Mexi
NCT04791449
Evaluating a Lifestyle Intervention to Prevent Recurrence of Diabetic Foot Ulcers
University of Southern California
NCT06487780
A Phase 2a Proof of Concept Open-Label, Randomized, Controlled Study to Evaluate the Safety and Efficacy of MDI-1228-mesylate Gel Compared With Standard of Care Alone in Patients With Diabetic Foot Ulcers
Zhuhai Rui-Inno Pharmaceutical Technology Co.
NCT06852976
Evaluating the Durability of Closure for Diabetic Foot Ulcers Following a Randomized, Controlled, Modified Platform Trial.
Applied Biologics
NCT07360418
A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers.
BioLab Holdings
NCT07364630
NOX1416 in Treatment of Chronic Non-Healing Diabetic Foot Ulcers
NOxy Health Products
NCT06402565
Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.
Estar Medical dba Medical Technologies
NCT06810726
Adapting Lifestyle Offloading for DFUs
University of Southern California
NCT06278935
Mirragen Diabetic Foot Ulcer Study
The University of Texas Health Science Center at San Antonio
NCT06598241
Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers
Eluciderm
NCT07396376
Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Diabetic Foot Ulcers
NuScience Medical Biologics
NCT07039396
Geko™ Cross Therapy Registry - Wound
Firstkind
NCT05007301
Study Evaluating Several CAMPs in Nonhealing Diabetic Foot and Venous Leg Ulcers
Cellution Biologics
NCT06562296
A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot
Medaxis
NCT04564443
Efficacy of ProgenaMatrix™ in the Management of DFUs
ProgenaCare Global
NCT06292026
Omega3 Wound Fish Skin Graft in the Treatment of DFUs
Kerecis
NCT04133493
Non-healing Diabetic Foot Ulcers Treated With Standard Care With or Without BR-AM
BioStem Technologies
NCT06565156
Sterilised, Porcine Placental Tissue in the Treatment of Chronic Diabetic Foot Ulcers
ConvaTec
NCT05687656
Wound Assessment Using Spectral Imaging US
SpectralMD
NCT05415683
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 6 |
| Phase 3 | 2 |
| Phase 4 | 7 |
Top Sponsors
Named interventions
Most-linked intervention names on Diabetic Foot Ulcer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Diabetic Foot Ulcer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Diabetic Foot Ulcer page
68 registered trials, 42 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 42 Diabetic Foot Ulcer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Applied Biologics sponsors the most Diabetic Foot Ulcer trials on record, review their full trial history before evaluating a specific study. See Applied Biologics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diabetic Foot Ulcer condition card totals 68 registered trials; most-linked intervention Standard of Care; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.