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ClinicalTrials.gov 20 recruiting now early-phase tilt

Stress Disorders, Post-Traumatic: early-phase trial registry

20 of 68 indexed Stress Disorders, Post-Traumatic trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #203 of 28,707 conditions by registered trial count.

68 US clinical trials · 20 currently recruiting · #203 of 28,707 conditions by registered trial count

Stress Disorders, Post-Traumatic: 68 US clinical trials tracked, 20 recruiting.

Stress Disorders, Post-Traumatic is the subject of 68 registered US clinical trials on ClinicalTrials.gov, 20 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 19 of these trials.

Enrollment posture brief

Registry condition stress-disorders-post-traumatic

OPEN 20 | RECR 29% | LATE 7 | EARLY 11 | RANK #203 | SPON 19

Nearest open-share peer: Addiction (29% recruiting · 17 trials)

Diabetic Foot Ulcer61.8%Brain Metastases60.3%Refractory Multiple Myeloma33.8%Stress Disorders, Post-T (th…29%Acne Vulgaris2.9%
Open-enrollment share among volume-matched conditions near Stress Disorders, Post-Traumatic

Stress Disorders, Post-Traumatic lists 20 open slots (29% of 68 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stress Disorders, Post-Traumatic on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stress Disorders, Post-Traumatic is recruiting below its size-band peers.

    20 of 68 indexed trials (29.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Stress Disorders, Post-Traumatic research.

    VA Office of Research and Development accounts for 19 of 68 trials (27.9%). 42 distinct sponsors appear on at least one study for this condition label.

  3. Typical Stress Disorders, Post-Traumatic enrolment sits around 84 participants.

    Median target enrolment is 84 among the 67 trials that report a genuine target (sentinel values excluded). 37 of those (55.2%) plan for fewer than 100 participants.

  4. Stress Disorders, Post-Traumatic research is mostly interventional.

    61 interventional and 7 observational studies make up this index (89.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 28Phase 33Phase 44

Open and recent trials

68 total, page 2 of 2

COMPLETED Phase 1 60 participants

Trial of Paroxetine-CR for the Treatment of Patients With Post Traumatic Stress Disorder Remaining Symptomatic After Initial Exposure Therapy

Massachusetts General Hospital

NCT00121888

COMPLETED NA 59 participants

Cornerstone Program for Transition-Age Youth Study Protocol for a Randomized Controlled Trial

New York University

NCT02696109

COMPLETED NA 55 participants

Investigation of the Freespira Breathing System in the Treatment of Post Traumatic Stress Disorder (PTSD)

Palo Alto Health Sciences

NCT03039231

COMPLETED NA 50 participants

Mindfulness Based Stress Reduction for Posttraumatic Stress Disorder: A Pilot Study

Seattle Institute for Biomedical and Clinical Research

NCT00880152

COMPLETED Phase 1 49 participants

Cognitive Therapy for PTSD in Addiction Treatment

Dartmouth-Hitchcock Medical Center

NCT00685451

COMPLETED NA 46 participants

Meditation in Veterans With PTSD and Mild TBI

VA Office of Research and Development

NCT02280304

COMPLETED NA 45 participants

A Cognitive Behavioral Therapy and Yoga Program for Trauma Symptoms

Georgetown University

NCT02368444

COMPLETED NA 45 participants

Suicide and Trauma Reduction Initiative Among VEterans

University of Utah

NCT03933059

COMPLETED Phase 2 41 participants

Ketamine as a Rapid Treatment for Post-traumatic Stress Disorder (PTSD)

Dennis Charney

NCT00749203

COMPLETED NA 37 participants

Information Processing Modification in PTSD (Oct. 18)

San Diego State University

NCT00601952

COMPLETED NA 32 participants

HIRREM in Military Personnel

Wake Forest University Health Sciences

NCT03230890

COMPLETED NA 30 participants

Adapting Treatment Delivery to Improve Retention in Evidence-Based PTSD Treatment

VA Office of Research and Development

NCT06335589

COMPLETED 30 participants

Ketamine Infusion Therapy for PTSD in Combat Veterans

Klarisana Physician Services P

NCT03088384

COMPLETED NA 30 participants

taVNS to Reduce PTSD Symptoms in WTC Responders

Northwell Health

NCT05212714

COMPLETED NA 19 participants

Wildlife and Wellbeing: An Animal-Assisted Intervention for Veterans With PTSD

University of Massachusetts, Worcester

NCT04116489

COMPLETED NA 13 participants

An Immersion Intervention for Symptoms of PTSD in Student Veterans

University of Nevada, Las Vegas

NCT05309031

COMPLETED NA 9 participants

Effectiveness of Prazosin in Bulimic Patients Experiencing Nightmares Due to PTSD

Milton S. Hershey Medical Center

NCT02382848

COMPLETED Phase 3

Fluoxetine vs EMDR to Treat Post-Traumatic Stress Disorder (PTSD)

Boston University

NCT00000379

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Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 8
Phase 3 3
Phase 4 4

Named interventions

Most-linked intervention names on Stress Disorders, Post-Traumatic records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Prolonged Exposure Therapy Behavioral
3 trials
Cognitive Processing Therapy Behavioral
3 trials
Placebo Drug
3 trials
Prazosin Drug
2 trials
Ketamine Drug
2 trials
Placebo Other
2 trials
Mifepristone Oral Tablet [Korlym] Drug
1 trials
Essential Skills therapy Behavioral
1 trials

US sites by state

Facility locations filed on Stress Disorders, Post-Traumatic trials. A trial with sites in several states counts in each.

California 16 trials
Massachusetts 9 trials
Washington 6 trials
Texas 6 trials
New York 6 trials
North Carolina 6 trials
Pennsylvania 5 trials
Maryland 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stress Disorders, Post-Traumatic page

68 registered trials, 20 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stress Disorders, Post-Traumatic condition card totals 68 registered trials; most-linked intervention Prolonged Exposure Therapy; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.