Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Malignant Solid Neoplasm
Open-data reference.
177 US clinical trials · 94 currently recruiting
Active & Recent Trials
Identifying and Caring for Individuals With Inherited Cancer Syndrome
OHSU Knight Cancer Institute
NCT04494945
The Vanguard Study: Testing a New Way to Screen for Cancer
National Cancer Institute (NCI)
NCT06995898
Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program
M.D. Anderson Cancer Center
NCT01772771
A Novel Molecular Approach to Blood DNA Screening for Cancer: Specificity Assessment (The NOMAD Study)
Mayo Clinic
NCT06192875
Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study
Mayo Clinic
NCT06304168
Collection and Storage of Tissue and Blood Samples From Patients With Cancer
National Cancer Institute LAO
NCT02474160
Impact of Physician Behavior on Cancer Distress
Mayo Clinic
NCT07325006
Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy
M.D. Anderson Cancer Center
NCT00991094
Role of Gut Microbiome in Cancer Therapy
Mayo Clinic
NCT05112614
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
SWOG Cancer Research Network
NCT04871542
A Virtual Community Health Educator for Increasing Clinical Trial Referrals Among Cancer Patients and Their Caregivers
Mayo Clinic
NCT07126496
Cancer Genetic Testing in Ethnic Populations
Mayo Clinic
NCT04475640
Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer
University of Washington
NCT01050504
Biomarkers to Predict Cancer Therapy-related Cardiotoxicity
Mayo Clinic
NCT06353191
Access to Genetic Testing in Underserved Patients With Cancer
University of Southern California
NCT06422455
Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy
SWOG Cancer Research Network
NCT05642611
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
ECOG-ACRIN Cancer Research Group
NCT06295367
Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial
University of Rochester
NCT05006482
A Collaborative Intervention for Improving Cancer Pain Management in Cancer Survivors (ASCENT)
Mayo Clinic
NCT06198010
Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment
NRG Oncology
NCT06279013
The Effect of COVID-19 Pandemic on Adolescent and Young Adult Cancer Patients and Survivors
M.D. Anderson Cancer Center
NCT04551378
Web-Based Toolkit to Improve Cancer-Related Emotional Distress and Anxiety in Rural Older Cancer Survivors
Northwestern University
NCT07290543
Expressive Writing for the Management of Stress in Cancer Survivors
M.D. Anderson Cancer Center
NCT04776941
Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Cancer Treatment
University of Rochester NCORP Research Base
NCT04829539
Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer Patients
Mayo Clinic
NCT06015932
Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning
Fred Hutchinson Cancer Center
NCT04515810
Increasing Knowledge and Interest in Cancer Clinical Trials
Hayley Thompson
NCT06501040
Duloxetine and Neurofeedback Training for the Treatment of Chemotherapy Induced Peripheral Neuropathy
M.D. Anderson Cancer Center
NCT04560673
INTERogating Cancer for Etiology, Prevention and Therapy Navigation
Mayo Clinic
NCT06008392
Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol
NRG Oncology
NCT03997370
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer
National Cancer Institute (NCI)
NCT03816345
Genetic Testing for the Prevention of Cancer in Indigenous American Communities (JUNIPER Trial)
Mayo Clinic
NCT06569316
Evaluating a Mobile Health Application Intervention for Caregiver Instruction in Manual Therapy for Chemotherapy-Induced Peripheral Neuropathy
Mayo Clinic
NCT06945380
Wearable Activity Tracking to Curb Hospitalizations
University of California, San Francis
NCT06587100
Non-invasive Ventilation in Reducing the Need for Intubation in Patients With Cancer and Respiratory Failure
M.D. Anderson Cancer Center
NCT02464696
The Impact of COVID-19 on Pulmonary Procedures
M.D. Anderson Cancer Center
NCT05022446
Provider-Mediated Communication of Genetic Testing Results to At-Risk Relatives of Cancer Patients to Improve Genetic Counseling and Testing Rates, Family HOPE Study
City of Hope Medical Center
NCT05772130
Telemedicine for Improvement of Care for Older Adults With Cancer in the Underserved Community, The GAIN-S Trial
City of Hope Medical Center
NCT06022965
Outreach Project to Connect Underrepresented Populations to Clinical Trials at Ohio State University, CUSP2CT Project Trial
Ohio State University Comprehensive Cancer Center
NCT06314672
Community-Based Physical Activity Intervention for Underserved Cancer Survivors
Roswell Park Cancer Institute
NCT06206863
Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)
Ohio State University Comprehensive Cancer Center
NCT05178472
Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers
AIDS Malignancy Consortium
NCT05663502
Pre-Operative Guided Meditation to Reduce Pre-Operative Anxiety in Patients Undergoing Cancer-Directed Surgery
Ohio State University Comprehensive Cancer Center
NCT06949943
Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment Planning
Mayo Clinic
NCT06200116
Acceptance and Commitment Therapy and Compassion-Based Virtual Group Therapy to Improve Psychological Wellbeing in Patients With Cancer
Mayo Clinic
NCT06246955
A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study
Children's Oncology Group
NCT06410209
Complications and Clinical Response in Cancer Patients Treated With Anti-VEGF-Related Therapies
M.D. Anderson Cancer Center
NCT05108519
Wisconsin Ginseng for Decreasing Cancer Related Fatigue
Mayo Clinic
NCT06395441
Community-Based Exercise and Nutrition Training and Education Program for Cancer Survivors
Roswell Park Cancer Institute
NCT06565260
Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
Mayo Clinic
NCT06788886
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors
Mayo Clinic
NCT03750227
Ambient Sensing Room to Detect Early Signs of Adverse Events in Hospitalized Patients With Cancer
Mayo Clinic
NCT07477886
Communication Issues in Patient and Provider Discussions of Immunotherapy
Emory University
NCT05873608
Weighted Blanket Use to Reduce Anxiety in Oncology Patients
Ohio State University Comprehensive Cancer Center
NCT06089408
A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients
Children's Oncology Group
NCT05711667
Investigating Memory and Physical Activity After Cancer Treatment in Survivors of Adolescent and Young Adult Cancers
Mayo Clinic
NCT06880861
Observational Study of Sex Differences in Symptoms During Immune Checkpoint Inhibitor Treatment for People With Cancer
OHSU Knight Cancer Institute
NCT06562777
Intravital Microscopy in Human Solid Tumors
Mayo Clinic
NCT03823144
A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients
University of Michigan Rogel Cancer Center
NCT07291414
Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed Therapy
Mayo Clinic
NCT06723041
Transportation for Cancer Care Navigation Tool for Reducing Travel Barriers Among Patients With Solid Tumors Receiving Radiation Therapy
Emory University
NCT06541158
CREATE: Art for Children With Cancer
OHSU Knight Cancer Institute
NCT06342453
Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines
M.D. Anderson Cancer Center
NCT02962661
Cryocompression With or Without Cilostazol for the Prevention of Paclitaxel-induced Neuropathy in Patients With Gynecological Cancers
Emory University
NCT06492070
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
M.D. Anderson Cancer Center
NCT04565665
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
National Cancer Institute (NCI)
NCT06126276
Exercise Program (TEAM Me) for the Improvement of Movement and Mobility in Pediatric and Adolescent and Young Adult Patients With Cancer Undergoing a Blood Stem Cell Transplant
M.D. Anderson Cancer Center
NCT04678427
Aromatherapy Essential Oils to Manage Anxiety and Nausea in Cancer Patients Receiving Infusion in the Ambulatory Setting
City of Hope Medical Center
NCT07126301
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
Children's Oncology Group
NCT06513962
Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers
City of Hope Medical Center
NCT05722288
Solution-Focused Brief Therapy for Support of Psychological Distress in Adolescent and Young Adult Cancer Survivors
University of Michigan Rogel Cancer Center
NCT06941324
Group Curriculum for Improving Survivorship Outcomes in Adolescent and Young Adult Cancer Survivors
Mayo Clinic
NCT05584449
Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas
Roswell Park Cancer Institute
NCT06202066
Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction
Roswell Park Cancer Institute
NCT06306638
Different Types of Massage Therapy to Reduce Anxiety During Chemotherapy Infusion in Patients With Cancer
City of Hope Medical Center
NCT07184294
A Virtually Delivered Diet Intervention (LASO-3) for the Improvement of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors Post-treatment
University of Michigan Rogel Cancer Center
NCT07365007
L-Theanine to Support Relaxation and Mood for Cancer Patients in Surveillance
City of Hope Medical Center
NCT07220447
Data-Driven Strategies for Patient Engagement About Cancer Clinical Trials
University of Southern California
NCT07456436
Telehealth Intervention for Improving Distress and Financial Toxicity in the Caregivers
Wake Forest University Health Sciences
NCT06709404
Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer Survivors
City of Hope Medical Center
NCT06500377
Voices: Messages of Wisdom and Hope in the Face of Illness
Mayo Clinic
NCT07381179
Evaluation of Early Identification of Cognitive Side Effects of Immunotherapy
Masonic Cancer Center, University of Minnesota
NCT06414278
Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma
City of Hope Medical Center
NCT05830058
Mobile App to Help Survivors of Childhood Cancer Navigate Long-Term Follow-Up Care
University of California, San Francis
NCT05641961
Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer Patients
M.D. Anderson Cancer Center
NCT05101213
A Mindfulness-Based Stress Reduction Program for Improving Mental Health Outcomes for Underserved Cancer Patients in Minnesota
Mayo Clinic
NCT07291011
Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion
M.D. Anderson Cancer Center
NCT06184321
Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events
Mayo Clinic
NCT06640010
Virtual Reality for Symptom Management in Patients Undergoing Hematopoietic Stem Cell Transplantation
Roswell Park Cancer Institute
NCT06798701
Ex Vivo Expansion (ACT-X)
Mayo Clinic
NCT07137312
Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment
Mayo Clinic
NCT07221409
Virtual Art Therapy Assisted Re-Integration to Improve Biopsychosocial Outcomes in Adolescent and Young Adult Cancer Survivors, AVATARS Trial
Mayo Clinic
NCT07089927
Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life With Chemotherapy-Induced Peripheral Neuropathy
Mayo Clinic
NCT05411523
Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi Method
M.D. Anderson Cancer Center
NCT05054413
Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 Pandemic
M.D. Anderson Cancer Center
NCT04500600
An Observational Research Study for Cancer Patients on Immune Checkpoint Inhibitors, DiRECT Study
University of Rochester NCORP Research Base
NCT05364086
NCI COVID-19 in Cancer Patients, NCCAPS Study
National Cancer Institute (NCI)
NCT04387656
Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors
M.D. Anderson Cancer Center
NCT04447222
Financial Toxicity in Cancer Patients
M.D. Anderson Cancer Center
NCT04592250
Yoga Program for Improving the Quality of Life in Couples Coping With Cancer
M.D. Anderson Cancer Center
NCT04607590
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 24 |
| Phase 2 | 22 |
| Phase 3 | 12 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Malignant Solid Neoplasm Trial Landscape
ClinicalTrials.gov lists 177 US studies indexed under Malignant Solid Neoplasm, and 94 of those are currently open to recruitment — roughly 53% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Malignant Solid Neoplasm shows 14 late-stage studies (Phase 3 and Phase 4 combined) alongside 46 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Malignant Solid Neoplasm is led by M.D. Anderson Cancer Center with 42 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Malignant Solid Neoplasm?
PlainTrial tracks 177 US clinical trials for Malignant Solid Neoplasm, of which 94 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Malignant Solid Neoplasm?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.