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Malignant Solid Neoplasm: early-phase trial registry
94 of 177 indexed Malignant Solid Neoplasm trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #62 of 28,707 conditions by registered trial count.
177 US clinical trials · 94 currently recruiting · #62 of 28,707 conditions by registered trial count
Malignant Solid Neoplasm: 177 US clinical trials tracked, 94 recruiting.
Malignant Solid Neoplasm is the subject of 177 registered US clinical trials on ClinicalTrials.gov, 94 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 46 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 42 of these trials.
Enrollment posture brief
Registry condition malignant-solid-neoplasm
OPEN 94 | RECR 53% | LATE 14 | EARLY 46 | RANK #62 | SPON 42
Volume-matched condition peers
Nearest open-share peer: Endometriosis (53% recruiting · 49 trials)
Malignant Solid Neoplasm lists 94 open slots (53% of 177 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Malignant Solid Neoplasm on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Malignant Solid Neoplasm is recruiting above its size-band peers.
94 of 177 indexed trials (53.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Malignant Solid Neoplasm research.
M.D. Anderson Cancer Center accounts for 42 of 177 trials (23.7%). 29 distinct sponsors appear on at least one study for this condition label.
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Typical Malignant Solid Neoplasm enrolment sits around 105 participants.
Median target enrolment is 105 among the 177 trials that report a genuine target (sentinel values excluded). 84 of those (47.5%) plan for fewer than 100 participants.
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Malignant Solid Neoplasm research is mostly interventional.
128 interventional and 49 observational studies make up this index (72.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
177 total, page 1 of 4
Identifying and Caring for Individuals With Inherited Cancer Syndrome
OHSU Knight Cancer Institute
NCT04494945
The Vanguard Study: Testing a New Way to Screen for Cancer
National Cancer Institute (NCI)
NCT06995898
Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program
M.D. Anderson Cancer Center
NCT01772771
A Novel Molecular Approach to Blood DNA Screening for Cancer: Specificity Assessment (The NOMAD Study)
Mayo Clinic
NCT06192875
Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study
Mayo Clinic
NCT06304168
Collection and Storage of Tissue and Blood Samples From Patients With Cancer
National Cancer Institute LAO
NCT02474160
Impact of Physician Behavior on Cancer Distress
Mayo Clinic
NCT07325006
Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy
M.D. Anderson Cancer Center
NCT00991094
Role of Gut Microbiome in Cancer Therapy
Mayo Clinic
NCT05112614
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
SWOG Cancer Research Network
NCT04871542
A Virtual Community Health Educator for Increasing Clinical Trial Referrals Among Cancer Patients and Their Caregivers
Mayo Clinic
NCT07126496
Cancer Genetic Testing in Ethnic Populations
Mayo Clinic
NCT04475640
Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer
University of Washington
NCT01050504
Biomarkers to Predict Cancer Therapy-related Cardiotoxicity
Mayo Clinic
NCT06353191
Access to Genetic Testing in Underserved Patients With Cancer
University of Southern California
NCT06422455
Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy
SWOG Cancer Research Network
NCT05642611
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
ECOG-ACRIN Cancer Research Group
NCT06295367
Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial
University of Rochester
NCT05006482
A Collaborative Intervention for Improving Cancer Pain Management in Cancer Survivors (ASCENT)
Mayo Clinic
NCT06198010
Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment
NRG Oncology
NCT06279013
The Effect of COVID-19 Pandemic on Adolescent and Young Adult Cancer Patients and Survivors
M.D. Anderson Cancer Center
NCT04551378
Web-Based Toolkit to Improve Cancer-Related Emotional Distress and Anxiety in Rural Older Cancer Survivors
Northwestern University
NCT07290543
Expressive Writing for the Management of Stress in Cancer Survivors
M.D. Anderson Cancer Center
NCT04776941
Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Cancer Treatment
University of Rochester NCORP Research Base
NCT04829539
Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer Patients
Mayo Clinic
NCT06015932
Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning
Fred Hutchinson Cancer Center
NCT04515810
Increasing Knowledge and Interest in Cancer Clinical Trials
Hayley Thompson
NCT06501040
Duloxetine and Neurofeedback Training for the Treatment of Chemotherapy Induced Peripheral Neuropathy
M.D. Anderson Cancer Center
NCT04560673
INTERogating Cancer for Etiology, Prevention and Therapy Navigation
Mayo Clinic
NCT06008392
Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol
NRG Oncology
NCT03997370
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer
National Cancer Institute (NCI)
NCT03816345
Genetic Testing for the Prevention of Cancer in Indigenous American Communities (JUNIPER Trial)
Mayo Clinic
NCT06569316
Evaluating a Mobile Health Application Intervention for Caregiver Instruction in Manual Therapy for Chemotherapy-Induced Peripheral Neuropathy
Mayo Clinic
NCT06945380
Wearable Activity Tracking to Curb Hospitalizations
University of California, San Francisco
NCT06587100
Non-invasive Ventilation in Reducing the Need for Intubation in Patients With Cancer and Respiratory Failure
M.D. Anderson Cancer Center
NCT02464696
The Impact of COVID-19 on Pulmonary Procedures
M.D. Anderson Cancer Center
NCT05022446
Provider-Mediated Communication of Genetic Testing Results to At-Risk Relatives of Cancer Patients to Improve Genetic Counseling and Testing Rates, Family HOPE Study
City of Hope Medical Center
NCT05772130
Telemedicine for Improvement of Care for Older Adults With Cancer in the Underserved Community, The GAIN-S Trial
City of Hope Medical Center
NCT06022965
Outreach Project to Connect Underrepresented Populations to Clinical Trials at Ohio State University, CUSP2CT Project Trial
Ohio State University Comprehensive Cancer Center
NCT06314672
Community-Based Physical Activity Intervention for Underserved Cancer Survivors
Roswell Park Cancer Institute
NCT06206863
Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)
Ohio State University Comprehensive Cancer Center
NCT05178472
Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers
AIDS Malignancy Consortium
NCT05663502
Pre-Operative Guided Meditation to Reduce Pre-Operative Anxiety in Patients Undergoing Cancer-Directed Surgery
Ohio State University Comprehensive Cancer Center
NCT06949943
Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment Planning
Mayo Clinic
NCT06200116
Acceptance and Commitment Therapy and Compassion-Based Virtual Group Therapy to Improve Psychological Wellbeing in Patients With Cancer
Mayo Clinic
NCT06246955
A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study
Children's Oncology Group
NCT06410209
Complications and Clinical Response in Cancer Patients Treated With Anti-VEGF-Related Therapies
M.D. Anderson Cancer Center
NCT05108519
Wisconsin Ginseng for Decreasing Cancer Related Fatigue
Mayo Clinic
NCT06395441
Community-Based Exercise and Nutrition Training and Education Program for Cancer Survivors
Roswell Park Cancer Institute
NCT06565260
Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
Mayo Clinic
NCT06788886
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 24 |
| Phase 2 | 22 |
| Phase 3 | 12 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Malignant Solid Neoplasm records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Malignant Solid Neoplasm trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Malignant Solid Neoplasm page
177 registered trials, 94 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 94 Malignant Solid Neoplasm trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- M.D. Anderson Cancer Center sponsors the most Malignant Solid Neoplasm trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Malignant Solid Neoplasm condition card totals 177 registered trials; most-linked intervention Questionnaire Administration; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.