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NCT06011876 · ClinicalTrials.gov registry record · NA
BioFLO for Respiratory Recovery in SCI
A NA study of Spinal Cord Injuries, sponsored by University of Florida.
- Recruiting
- Registry status
- NA
- Development phase
- 62
- Enrollment target
- 1
- Study location
NCT06011876: Recruiting NA study of Spinal Cord Injuries, sponsored by University of Florida.
NCT06011876 is a NA study of Spinal Cord Injuries that is actively recruiting participants, run by University of Florida. The registered enrollment target is 62 participants, roughly in line with the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06011876, a NA study of Spinal Cord Injuries, is actively recruiting participants, sponsored by University of Florida.
- RECRUITING
- Registry status
- NA
- Development phase
- 62 participants
- Enrollment target
- 1
- Study location
Study Summary
Acute intermittent hypoxia (AIH) involves brief (1 min), repeated episodes (\~15) of breathing low oxygen air to stimulate spinal neuroplasticity. Animal and human studies show that AIH improves motor function after spinal cord injury, particularly with slightly increased carbon dioxide (hypercapnic AIH; AIHH) and task-specific training. Using a double blind cross-over design, the study will test whether AIHH improves breathing more than AIH and whether specific genetic variations are related to individuals' intervention responses.
Primary Outcome
The change in peak-to-peak amplitude of the motor evoked potential of the diaphragm will be tested using transcranial magnetic stimulation.
Conditions Studied
Interventions
- OTHER Acute Intermittent Hypercapnic-Hypoxia (AIHH)
- OTHER Sham AIH
- OTHER Acute Intermittent Hypoxia (AIH)
Study Locations (1)
Florida
- Brooks Rehabilitation - Jacksonville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 62 participants |
| Start Date | 2023-12-21 |
| Est. Completion | 2027-09 |
| Phase | NA |
What NCT06011876 shows while recruiting
NCT06011876 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 62 participants, a relatively small participant target, roughly in line with the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target.
The record links to 1 condition, with Spinal Cord Injuries appearing as the primary indexed condition, and to 3 interventions - of which Acute Intermittent Hypercapnic-Hypoxia (AIHH) is the first listed.
NCT06011876 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT06011876 about?
NCT06011876 is a clinical study titled "BioFLO for Respiratory Recovery in SCI". Acute intermittent hypoxia (AIH) involves brief (1 min), repeated episodes (\~15) of breathing low oxygen air to stimulate spinal neuroplasticity. Animal and human studies show that AIH improves motor function after spinal cord injury, particularly with slightly increased carbon dioxide (hypercapnic...
What is the current status of trial NCT06011876?
This trial is currently recruiting. It is a NA study. The enrollment target is 62 participants. The study started on 2023-12-21. Estimated completion is 2027-09.
What conditions does trial NCT06011876 study?
This clinical trial studies the following conditions: Spinal Cord Injuries.
What interventions are being tested in trial NCT06011876?
The interventions under investigation include: Acute Intermittent Hypercapnic-Hypoxia (AIHH) (OTHER), Sham AIH (OTHER), Acute Intermittent Hypoxia (AIH) (OTHER).
Who is sponsoring clinical trial NCT06011876?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06011876 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spinal Cord Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06011876's enrollment target sits among peer trials
62 47th of 202 higher than 156 of 202 other Spinal Cord Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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