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Dementia clinical trials
79 of 202 indexed Dementia trials are currently recruiting.
202 US clinical trials · 79 currently recruiting
Dementia is the subject of 202 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 8 of these trials.
The research picture
Dementia has 202 registered US clinical trials, 79 of them open to new participants right now, about 39% of the total.
- 79
- recruiting participants now
- 39%
- of trials open to enrollment
- 13
- in Phase 3–4 (later-stage)
- 8
- top sponsor: University of Washington
Active & Recent Trials
202 total, page 1 of 5
Alzheimer's Prevention Registry: A Program to Accelerate Enrollment Into Studies
Banner Health
NCT02022943
Alzheimer Prevention Trials (APT) Webstudy
University of Southern California
NCT03638583
TabCAT Brain Health Assessment in Primary Care
University of California, San Francisco
NCT06090578
Primary Care Detection of Cognitive Impairment Leveraging Health & Consumer Technologies in Underserved Communities: The MyCog Trial
Northwestern University
NCT05607732
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Duke University
NCT04262206
Genetic Characterization of Movement Disorders and Dementias
National Institute on Aging (NIA)
NCT02014246
Alzheimer's Disease Genetics Study
Indiana University
NCT00064870
NYSCF Scientific Discovery Biobank
New York Stem Cell Foundation Research Institute
NCT06203106
5-Cog 2.0: A Pragmatic Clinical Trial
Albert Einstein College of Medicine
NCT05515224
Clinical Applications of Advanced Ophthalmic Imaging
University of Miami
NCT03135327
Phase I Human Analytics (HALO) Study
HALO Diagnostics
NCT05423860
The INSPIRE Study: Intervention Strategies for Preserving Intellectual Resilience and Engagement
Healthy Minds Initiative
NCT06741865
Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy
Alzheimer's Light
NCT03657745
Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers
University of Washington
NCT05596760
Study to Understand Novel Biomarkers in Researching Dementia
Washington University School of Medicine
NCT06547099
Evaluating a National Person-Centered Training Program to Strengthen the Dementia Care Workforce
University of North Carolina, Chapel Hill
NCT06239688
The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia
University of Alabama at Birmingham
NCT04171323
DC Longitudinal Study on Aging and Specimen Bank
Georgetown University
NCT03702907
Tennessee Alzheimer's Project
Vanderbilt University Medical Center
NCT05372172
Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0
Hebrew SeniorLife
NCT05950607
Paradoxical Lucidity in Severe End-Stage Dementia
NYU Langone Health
NCT05234866
ADRC Clinical Cohort (Alzheimer's Disease)
Duke University
NCT06703541
Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase
University of Alabama, Tuscaloo
NCT05820919
Trial-Ready Cohort-Down Syndrome (TRC-DS)
University of Southern California
NCT04165109
Evaluating the Efficacy of the Pain Identification and Communication Toolkit
Weill Medical College of Cornell University
NCT06168604
Dementia and Diabetes Prevention Program
University of California, Davis
NCT04141878
Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's
Florida State University
NCT05748613
Connect-Home: Alzheimer's Disease and Related Dementias
University of North Carolina, Chapel Hill
NCT06840587
Persons With Dementia and Their Extended Family Caregivers
Karen Roberto
NCT04863859
Enhancing Triadic Communication About Cognition for Older Adults With Alzheimer's Disease or Related Dementias Facing a Cancer Management Decision
University of Rochester
NCT06313853
HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms
Johns Hopkins University
NCT06930560
Testing the Pain Clinical Practice Guideline
University of Maryland, Baltimore
NCT05858996
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Washington University School of Medicine
NCT06647498
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Washington University School of Medicine
NCT05552157
Caregiver as Navigator: Develop Skills Online (CAN-DO)
Emory University
NCT06177990
Coaching Dementia Caregivers to Master Care-Resistant Behavior
University of Alabama at Birmingham
NCT05098652
δ in Dementia Clinical Trials
The University of Texas Health Science Center at San Antonio
NCT05592678
Learning Skills Together Family Caregiver Complex Intervention
Case Western Reserve University
NCT05846984
Dementia Caregivers' Link to Assistance and Resources
Visiting Nurse Service of New York
NCT06860035
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
National Institute of Mental Health (NIMH)
NCT04396873
Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium
Massachusetts General Hospital
NCT06052397
Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia
Hebrew SeniorLife
NCT05661084
Dementia Care Partner Hospital Assessment Tool
University of Wisconsin, Madison
NCT05592366
Door-Through-Door Companion Rideshare Technology for Individuals With Alzheimer's Disease and Related Dementias (AD/ADRD)
Onward Health
NCT06850870
Improving PCP Advance Care Planning for People With ADRD
University of Pittsburgh
NCT06565169
Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia
University of Texas at Austin
NCT06511752
The BRAIN App (Phase 2 SBIR)
Hopeful Aging
NCT06298474
Effect of Cognitive Empathy Training on Dementia Caregivers
Emory University
NCT06650527
First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia
David Wilson
NCT05374278
NiteCAPP: Web-based Interventions for Insomnia in Rural Dementia Caregivers
University of South Florida
NCT04896775
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 19 |
| Phase 3 | 10 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Dementia Trial Landscape
202 indexed Dementia studies · 79 recruiting (39%).
Phase mix: 13 late (III/IV) vs 29 early (I/II).
Top sponsor: University of Washington (8 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Dementia?
PlainTrial tracks 202 US clinical trials for Dementia, of which 79 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Dementia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.