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NCT06451133 · ClinicalTrials.gov registry record · NA
Hemodynamic Management Following Acute Traumatic Spinal Cord Injury
A NA study of Spinal Cord Injuries, sponsored by The University of Texas Health Science Center, Houston.
- Recruiting
- Registry status
- NA
- Development phase
- 228
- Enrollment target
- 1
- Study location
NCT06451133: Recruiting NA study of Spinal Cord Injuries, sponsored by The University of Texas Health Science Center, Houston.
NCT06451133 is a NA study of Spinal Cord Injuries that is actively recruiting participants, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 228 participants, above the 60-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (280% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06451133, a NA study of Spinal Cord Injuries, is actively recruiting participants, sponsored by The University of Texas Health Science Center, Houston.
- RECRUITING
- Registry status
- NA
- Development phase
- 228 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to assess the effect of various hemodynamic management strategies on functional neurologic outcomes and non-neurologic adverse events in the first 5 days following acute spinal cord injury (SCI). The hemodynamic management strategies assessed include targeting a mean arterial blood pressure (MAP) goal of 85-90 mmHg, targeting a spinal cord perfusion pressure (SCPP) goal of ≥65 mmHg, or targeting normal hemodynamics, which is a MAP goal of ≥65 mmHg.
Primary Outcome
Upper and lower extremities will be assessed, and motor strength at each spinal cord level will be scored from 0 to 5 (0 indicates total paralysis and 5 indicates active movement against full resistance), with a maximum score of 25 for each extremity, totaling 100 for all four extremities. Total score ranges from 0 to 100, with a higher score indicating a better outcome.
Conditions Studied
Interventions
- OTHER Mean arterial blood pressure (MAP) goal of ≥65 mmHg
- OTHER Mean arterial blood pressure (MAP) goal of 85-90 mmHg
- OTHER Spinal cord perfusion pressure (SCPP) goal of ≥65 mmHg
Study Locations (1)
Texas
- The University of Texas Health Science Center at Houston - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 228 participants |
| Start Date | 2024-07-03 |
| Est. Completion | 2026-07-31 |
| Phase | NA |
What NCT06451133 shows while recruiting
NCT06451133 is an interventional study that assigns participants to a tested intervention. The registered 228 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (280% higher).
The record links to 1 condition, with Spinal Cord Injuries appearing as the primary indexed condition, and to 3 interventions - of which Mean arterial blood pressure (MAP) goal of ≥65 mmHg is the first listed.
NCT06451133 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06451133 about?
NCT06451133 is a clinical study titled "Hemodynamic Management Following Acute Traumatic Spinal Cord Injury". The purpose of this study is to assess the effect of various hemodynamic management strategies on functional neurologic outcomes and non-neurologic adverse events in the first 5 days following acute spinal cord injury (SCI). The hemodynamic management strategies assessed include targeting a mean art...
What is the current status of trial NCT06451133?
This trial is currently recruiting. It is a NA study. The enrollment target is 228 participants. The study started on 2024-07-03. Estimated completion is 2026-07-31.
What conditions does trial NCT06451133 study?
This clinical trial studies the following conditions: Spinal Cord Injuries.
What interventions are being tested in trial NCT06451133?
The interventions under investigation include: Mean arterial blood pressure (MAP) goal of ≥65 mmHg (OTHER), Mean arterial blood pressure (MAP) goal of 85-90 mmHg (OTHER), Spinal cord perfusion pressure (SCPP) goal of ≥65 mmHg (OTHER).
Who is sponsoring clinical trial NCT06451133?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06451133 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spinal Cord Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06451133's enrollment target sits among peer trials
228 9th of 202 higher than 194 of 202 other Spinal Cord Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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