Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 108 recruiting now official registry

Spinal Cord Injuries clinical trials

108 of 203 indexed Spinal Cord Injuries trials are currently recruiting.

203 US clinical trials · 108 currently recruiting

Spinal Cord Injuries is the subject of 203 registered US clinical trials on ClinicalTrials.gov, 108 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is University of Louisville, running 9 of these trials.

The research picture

Spinal Cord Injuries has 203 registered US clinical trials, 108 of them open to new participants right now, about 53% of the total.

108
recruiting participants now
53%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
9
top sponsor: University of Louisville
Phase 112Phase 214Phase 32Phase 43

Active & Recent Trials

203 total, page 2 of 5

RECRUITING 35 participants

Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury

University of Alabama at Birmingham

NCT05670288

RECRUITING NA 30 participants

Spinal Cord Stimulation and Respiration After Injury

University of Louisville

NCT05178056

RECRUITING Phase 1 30 participants

Bacteriophage Therapy in Spinal Cord Injury Patients With Bacteriuria

Barbara Wells Trautner

NCT06559618

RECRUITING NA 30 participants

Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain

University of Miami

NCT06010251

RECRUITING NA 30 participants

Multi-speed Ergonomic Wheelchair

VA Office of Research and Development

NCT05776030

RECRUITING NA 30 participants

Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury

Anne Bryden

NCT02329652

RECRUITING Phase 2 30 participants

Effects of 5HTP on the Injured Human Spinal Cord

University of Alberta

NCT04520178

RECRUITING NA 30 participants

Extracorporeal Shockwave Therapy for Spasticity in People With Spinal Cord Injury

Kessler Foundation

NCT05432999

RECRUITING NA 27 participants

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia

Leigh R. Hochberg, MD, PhD.

NCT00912041

RECRUITING NA 26 participants

Spinal Cord Stimulation for Autonomic Recovery in Inpatient Rehabilitation After Acute SCI

University of Washington

NCT06540859

RECRUITING NA 25 participants

Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning

Medical University of South Carolina

NCT05094362

RECRUITING NA 24 participants

Dosing rTMS for Depression Post-SCI

VA Office of Research and Development

NCT05553353

RECRUITING Phase 2 24 participants

Sildenafil for Treatment of Urinary Incontinence in Patients With Spinal Cord Injuries

The University of Texas Medical Branch, Galveston

NCT04565925

RECRUITING NA 24 participants

Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Individuals With Spinal Cord Injuries

VA Office of Research and Development

NCT05351827

RECRUITING NA 24 participants

Remote Ischemic Conditioning for PwSCI

Washington University School of Medicine

NCT07488793

RECRUITING NA 24 participants

A Pilot RCT to Improve Cognitive Processing Speed in Acute SCI

Kessler Foundation

NCT06238492

RECRUITING Phase 2 21 participants

Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

North Florida Foundation for Research and Education

NCT04460872

RECRUITING NA 20 participants

Transcutaneous Spinal Stimulation and Exercise for Locomotion

University of Washington

NCT03509558

RECRUITING NA 20 participants

High Intensity Training for Neurological Injury Using Overground Exoskeletons in Inpatient Rehabilitation

The University of Texas Health Science Center, Houston

NCT04973852

RECRUITING Phase 2 20 participants

Epidural Stimulation and Resistance Training After SCI

United States Department of Defense

NCT04782947

RECRUITING NA 20 participants

Yoga Breath Training to Improve Cardiorespiratory Synchrony in Spinal Cord Injury

Spaulding Rehabilitation Hospital

NCT06514950

RECRUITING NA 20 participants

Early Intervention for Information Processing Speed Deficits in Acute SCI: A Pilot Study

Kessler Foundation

NCT06452264

RECRUITING NA 20 participants

Seated Balance Using the Indego™

James J. Peters Veterans Affairs Medical Center

NCT04047992

RECRUITING NA 20 participants

Transcutaneous Spinal Cord Stimulation in Children With Incomplete Spinal Cord Injury

Hugo W. Moser Research Institute at Kennedy Krieger

NCT06242873

RECRUITING NA 18 participants

AMPLIFY Study: Transcutaneous Spinal Direct Current Stimulation to Enhance Locomotor Rehabilitation After SCI

University of Florida

NCT05700942

RECRUITING NA 18 participants

Longitudinal Autonomic Characterization as a Predictor for Secondary Medical Complications Post-SCI

Mayo Clinic

NCT07210437

RECRUITING NA 16 participants

Locomotor and Bladder Function in Individuals With Acute Spinal Cord Injury

Claudia Angeli

NCT04879862

RECRUITING Early Phase 1 16 participants

Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury

University of Mississippi Medical Center

NCT06274021

RECRUITING NA 16 participants

Auricular Vagus Nerve Stimulation (aVNS) in Chronic Spinal Cord Injuries (SCI)

University of Miami

NCT06588608

RECRUITING Phase 1 16 participants

Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization

EG 427

NCT06596291

RECRUITING NA 16 participants

Transcutaneous Spinal Cord Stimulation Combined With Arm Bike for Cardiovascular Recovery in SCI

University of Washington

NCT06313515

RECRUITING NA 15 participants

Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI

Medical University of South Carolina

NCT05492188

RECRUITING NA 15 participants

Usability of the Adapted Rower for People With Spinal Cord Injury

University of South Carolina

NCT05959837

RECRUITING NA 15 participants

Abdominal Functional Electrical Stimulation to Improve Bowel Function in Spinal Cord Injury

Craig Hospital

NCT06345781

RECRUITING NA 15 participants

The Teaspoon Study - Telefitting Spinal Cord Stimulation for Pain

University of Minnesota

NCT05741788

RECRUITING NA 14 participants

Treatment of Depression Post-SCI

Medical University of South Carolina

NCT04263285

RECRUITING NA 13 participants

Diet and Exercise Solutions to Postprandial Hypotension

Ohio State University

NCT06882460

RECRUITING NA 13 participants

Grasp-Release Assessment of a Networked Neuroprosthesis Device

MetroHealth Medical Center

NCT05863754

RECRUITING NA 12 participants

Neuromodulation to Improve Respiratory Function in Cervical Spinal Cord Injury

University of California, Los Angeles

NCT04883463

RECRUITING NA 12 participants

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

University of California, San Francisco

NCT04144972

RECRUITING NA 12 participants

Finding the Best Combination of Brain and Spinal Cord Stimulation With Hand Training After Spinal Cord Injury

Bronx VA Medical Center

NCT06104735

RECRUITING NA 12 participants

Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)

Kessler Foundation

NCT05731986

RECRUITING NA 12 participants

Brain-Controlled Spinal Stimulation Walking Therapy After Incomplete Spinal Cord Injury (SCI)

University of Miami

NCT06406855

RECRUITING NA 12 participants

Augmenting Rehabilitation Outcomes and Functional Neuroplasticity Using Epidural Stimulation of Cervical Spinal Cord

The Methodist Hospital Research Institute

NCT06225245

RECRUITING NA 12 participants

Transcutaneous Spinal Stimulation for Lower Limb Spasticity in Spinal Cord Injury

University of Mississippi Medical Center

NCT05457205

RECRUITING NA 10 participants

Evaluation of an Advanced Lower Extremity Neuroprostheses

Case Western Reserve University

NCT00623389

RECRUITING NA 10 participants

Transcutaneous Spinal Stimulation: Safety and Feasibility for Upper Limb Function in Children With Spinal Cord Injury

University of Louisville

NCT04032990

RECRUITING NA 10 participants

Neurostimulation for Respiratory Function After Spinal Cord Injury

Shirley Ryan AbilityLab

NCT05756894

RECRUITING NA 10 participants

Spinal Decompression Plus Nerve Graft Implantation Following TSCI

Francis Farhadi

NCT06243211

RECRUITING NA 9 participants

Closed-loop Spinal Stimulation for Restoration of Upper Extremity Function After Spinal Cord Injury

University of Washington

NCT05267951

← Previous Page 2 of 5 Next →

Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 14
Phase 3 2
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Spinal Cord Injuries Trial Landscape

203 indexed Spinal Cord Injuries studies · 108 recruiting (53%).

Phase mix: 5 late (III/IV) vs 26 early (I/II).

Top sponsor: University of Louisville (9 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Spinal Cord Injuries?

PlainTrial tracks 203 US clinical trials for Spinal Cord Injuries, of which 108 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Spinal Cord Injuries?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.