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ClinicalTrials.gov 108 recruiting now early-phase tilt #47 of 28,707 conditions

Spinal Cord Injuries: early-phase trial registry

108 of 203 indexed Spinal Cord Injuries trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #47 of 28,707 conditions by registered trial count.

203 US clinical trials · 108 currently recruiting · #47 of 28,707 conditions by registered trial count

Spinal Cord Injuries: 203 US clinical trials tracked, 108 recruiting.

Spinal Cord Injuries is the subject of 203 registered US clinical trials on ClinicalTrials.gov, 108 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is University of Louisville, running 9 of these trials.

Enrollment posture brief

Registry condition spinal-cord-injuries

OPEN 108 | RECR 53% | LATE 5 | EARLY 26 | RANK #47 | SPON 9

Nearest open-share peer: Malignant Solid Neoplasm (53% recruiting · 177 trials)

Spinal Cord Injuries (this)53%Mild Cognitive Impairment48.5%Dementia39.1%Glioblastoma39%Atrial Fibrillation29.4%
Open-enrollment share among volume-matched conditions near Spinal Cord Injuries

Spinal Cord Injuries lists 108 open slots (53% of 203 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Spinal Cord Injuries on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Spinal Cord Injuries is recruiting above its size-band peers.

    108 of 203 indexed trials (53.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Spinal Cord Injuries trials is spread across many organizations.

    University of Louisville accounts for 9 of 203 trials (4.4%). 83 distinct sponsors appear on at least one study for this condition label.

  3. Most Spinal Cord Injuries trials plan to enrol fewer than 100 people.

    Median target enrolment is 30 among the 203 trials that report a genuine target (sentinel values excluded). 170 of those (83.7%) plan for fewer than 100 participants.

  4. Spinal Cord Injuries research is mostly interventional.

    180 interventional and 23 observational studies make up this index (88.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 112Phase 214Phase 32Phase 43

Open and recent trials

203 total, page 2 of 5

RECRUITING 35 participants

Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury

University of Alabama at Birmingham

NCT05670288

RECRUITING NA 30 participants

Spinal Cord Stimulation and Respiration After Injury

University of Louisville

NCT05178056

RECRUITING Phase 1 30 participants

Bacteriophage Therapy in Spinal Cord Injury Patients With Bacteriuria

Barbara Wells Trautner

NCT06559618

RECRUITING NA 30 participants

Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain

University of Miami

NCT06010251

RECRUITING NA 30 participants

Multi-speed Ergonomic Wheelchair

VA Office of Research and Development

NCT05776030

RECRUITING NA 30 participants

Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury

Anne Bryden

NCT02329652

RECRUITING Phase 2 30 participants

Effects of 5HTP on the Injured Human Spinal Cord

University of Alberta

NCT04520178

RECRUITING NA 30 participants

Extracorporeal Shockwave Therapy for Spasticity in People With Spinal Cord Injury

Kessler Foundation

NCT05432999

RECRUITING NA 27 participants

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia

Leigh R. Hochberg, MD, PhD.

NCT00912041

RECRUITING NA 26 participants

Spinal Cord Stimulation for Autonomic Recovery in Inpatient Rehabilitation After Acute SCI

University of Washington

NCT06540859

RECRUITING NA 25 participants

Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning

Medical University of South Carolina

NCT05094362

RECRUITING NA 24 participants

Dosing rTMS for Depression Post-SCI

VA Office of Research and Development

NCT05553353

RECRUITING Phase 2 24 participants

Sildenafil for Treatment of Urinary Incontinence in Patients With Spinal Cord Injuries

The University of Texas Medical Branch, Galveston

NCT04565925

RECRUITING NA 24 participants

Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Individuals With Spinal Cord Injuries

VA Office of Research and Development

NCT05351827

RECRUITING NA 24 participants

Remote Ischemic Conditioning for PwSCI

Washington University School of Medicine

NCT07488793

RECRUITING NA 24 participants

A Pilot RCT to Improve Cognitive Processing Speed in Acute SCI

Kessler Foundation

NCT06238492

RECRUITING Phase 2 21 participants

Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

North Florida Foundation for Research and Education

NCT04460872

RECRUITING NA 20 participants

Transcutaneous Spinal Stimulation and Exercise for Locomotion

University of Washington

NCT03509558

RECRUITING NA 20 participants

High Intensity Training for Neurological Injury Using Overground Exoskeletons in Inpatient Rehabilitation

The University of Texas Health Science Center, Houston

NCT04973852

RECRUITING Phase 2 20 participants

Epidural Stimulation and Resistance Training After SCI

United States Department of Defense

NCT04782947

RECRUITING NA 20 participants

Yoga Breath Training to Improve Cardiorespiratory Synchrony in Spinal Cord Injury

Spaulding Rehabilitation Hospital

NCT06514950

RECRUITING NA 20 participants

Early Intervention for Information Processing Speed Deficits in Acute SCI: A Pilot Study

Kessler Foundation

NCT06452264

RECRUITING NA 20 participants

Seated Balance Using the Indego™

James J. Peters Veterans Affairs Medical Center

NCT04047992

RECRUITING NA 20 participants

Transcutaneous Spinal Cord Stimulation in Children With Incomplete Spinal Cord Injury

Hugo W. Moser Research Institute at Kennedy Krieger

NCT06242873

RECRUITING NA 18 participants

AMPLIFY Study: Transcutaneous Spinal Direct Current Stimulation to Enhance Locomotor Rehabilitation After SCI

University of Florida

NCT05700942

RECRUITING NA 18 participants

Longitudinal Autonomic Characterization as a Predictor for Secondary Medical Complications Post-SCI

Mayo Clinic

NCT07210437

RECRUITING NA 16 participants

Locomotor and Bladder Function in Individuals With Acute Spinal Cord Injury

Claudia Angeli

NCT04879862

RECRUITING Early Phase 1 16 participants

Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury

University of Mississippi Medical Center

NCT06274021

RECRUITING NA 16 participants

Auricular Vagus Nerve Stimulation (aVNS) in Chronic Spinal Cord Injuries (SCI)

University of Miami

NCT06588608

RECRUITING Phase 1 16 participants

Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization

EG 427

NCT06596291

RECRUITING NA 16 participants

Transcutaneous Spinal Cord Stimulation Combined With Arm Bike for Cardiovascular Recovery in SCI

University of Washington

NCT06313515

RECRUITING NA 15 participants

Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI

Medical University of South Carolina

NCT05492188

RECRUITING NA 15 participants

Usability of the Adapted Rower for People With Spinal Cord Injury

University of South Carolina

NCT05959837

RECRUITING NA 15 participants

Abdominal Functional Electrical Stimulation to Improve Bowel Function in Spinal Cord Injury

Craig Hospital

NCT06345781

RECRUITING NA 15 participants

The Teaspoon Study - Telefitting Spinal Cord Stimulation for Pain

University of Minnesota

NCT05741788

RECRUITING NA 14 participants

Treatment of Depression Post-SCI

Medical University of South Carolina

NCT04263285

RECRUITING NA 13 participants

Diet and Exercise Solutions to Postprandial Hypotension

Ohio State University

NCT06882460

RECRUITING NA 13 participants

Grasp-Release Assessment of a Networked Neuroprosthesis Device

MetroHealth Medical Center

NCT05863754

RECRUITING NA 12 participants

Neuromodulation to Improve Respiratory Function in Cervical Spinal Cord Injury

University of California, Los Angeles

NCT04883463

RECRUITING NA 12 participants

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

University of California, San Francisco

NCT04144972

RECRUITING NA 12 participants

Finding the Best Combination of Brain and Spinal Cord Stimulation With Hand Training After Spinal Cord Injury

Bronx VA Medical Center

NCT06104735

RECRUITING NA 12 participants

Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)

Kessler Foundation

NCT05731986

RECRUITING NA 12 participants

Brain-Controlled Spinal Stimulation Walking Therapy After Incomplete Spinal Cord Injury (SCI)

University of Miami

NCT06406855

RECRUITING NA 12 participants

Augmenting Rehabilitation Outcomes and Functional Neuroplasticity Using Epidural Stimulation of Cervical Spinal Cord

The Methodist Hospital Research Institute

NCT06225245

RECRUITING NA 12 participants

Transcutaneous Spinal Stimulation for Lower Limb Spasticity in Spinal Cord Injury

University of Mississippi Medical Center

NCT05457205

RECRUITING NA 10 participants

Evaluation of an Advanced Lower Extremity Neuroprostheses

Case Western Reserve University

NCT00623389

RECRUITING NA 10 participants

Transcutaneous Spinal Stimulation: Safety and Feasibility for Upper Limb Function in Children With Spinal Cord Injury

University of Louisville

NCT04032990

RECRUITING NA 10 participants

Neurostimulation for Respiratory Function After Spinal Cord Injury

Shirley Ryan AbilityLab

NCT05756894

RECRUITING NA 10 participants

Spinal Decompression Plus Nerve Graft Implantation Following TSCI

Francis Farhadi

NCT06243211

RECRUITING NA 9 participants

Closed-loop Spinal Stimulation for Restoration of Upper Extremity Function After Spinal Cord Injury

University of Washington

NCT05267951

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Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 14
Phase 3 2
Phase 4 3

Named interventions

Most-linked intervention names on Spinal Cord Injuries records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
5 trials
Tests of sympathetic inhibition Diagnostic test
3 trials
Transcutaneous spinal stimulation Device
3 trials
Placebo Other
3 trials
BrainGate Neural Interface System Device
3 trials
I-Box by Dynatronics Device
2 trials
Combination of Neostigmine and Glycopyrrolate Drug
2 trials
Transcutaneous Spinal Cord Stimulation Device
2 trials

US sites by state

Facility locations filed on Spinal Cord Injuries trials. A trial with sites in several states counts in each.

Texas 26 trials
New York 23 trials
Florida 23 trials
California 17 trials
Massachusetts 15 trials
Illinois 14 trials
Pennsylvania 13 trials
New Jersey 13 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Spinal Cord Injuries page

203 registered trials, 108 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Spinal Cord Injuries condition card totals 203 registered trials; most-linked intervention Placebo; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.