Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05563103 · ClinicalTrials.gov registry record · NA
Combination Therapy to Improve SCI Recovery.
A NA study of Spinal Cord Injuries, sponsored by Spaulding Rehabilitation Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 2
- Study locations
NCT05563103: Recruiting NA study of Spinal Cord Injuries, sponsored by Spaulding Rehabilitation Hospital.
NCT05563103 is a NA study of Spinal Cord Injuries that is actively recruiting participants, run by Spaulding Rehabilitation Hospital. The registered enrollment target is 60 participants, roughly in line with the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target. The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05563103, a NA study of Spinal Cord Injuries, is actively recruiting participants, sponsored by Spaulding Rehabilitation Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study is to determine how combining bouts of low oxygen, transcutaneous spinal cord stimulation, and walking training may improve walking function for people with chronic spinal cord injury.
Primary Outcome
Participants walk ten meters without assistance at their fastest, but safest speed with a minimum of 1-minute of rest between two trials. Average speed across the up to three 10MWT trials will be used for analysis. Change is the difference between the post-treatment assessment 2 and pre-treatment baseline.
Conditions Studied
Interventions
- OTHER Daily acute intermittent hypoxia
- OTHER Room air (SHAM)
- OTHER Walking + tSTIM
- OTHER Walking + Sham transcutaneous spinal stimulation (tSHAM)
Study Locations (2)
Illinois
- Shirley Ryan AbilityLab - Chicago
Massachusetts
- Spaulding Rehabilitation Hospital - Cambridge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2023-01-17 |
| Est. Completion | 2026-12 |
| Phase | NA |
What NCT05563103 shows while recruiting
NCT05563103 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, roughly in line with the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target.
The record links to 1 condition, with Spinal Cord Injuries appearing as the primary indexed condition, and to 4 interventions - of which Daily acute intermittent hypoxia is the first listed.
NCT05563103 reports a single indexed study location in Illinois, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05563103 about?
NCT05563103 is a clinical study titled "Combination Therapy to Improve SCI Recovery.". The purpose of this study is to determine how combining bouts of low oxygen, transcutaneous spinal cord stimulation, and walking training may improve walking function for people with chronic spinal cord injury.
What is the current status of trial NCT05563103?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2023-01-17. Estimated completion is 2026-12.
What conditions does trial NCT05563103 study?
This clinical trial studies the following conditions: Spinal Cord Injuries.
What interventions are being tested in trial NCT05563103?
The interventions under investigation include: Daily acute intermittent hypoxia (OTHER), Room air (SHAM) (OTHER), Walking + tSTIM (OTHER), Walking + Sham transcutaneous spinal stimulation (tSHAM) (OTHER).
Who is sponsoring clinical trial NCT05563103?
This trial is sponsored by Spaulding Rehabilitation Hospital, which has 101 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05563103 being conducted?
This trial has 2 study locations across Illinois, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spinal Cord Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05563103's enrollment target sits among peer trials
60 48th of 202 higher than 145 of 202 other Spinal Cord Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)
RECRUITING · NA
-
Closed-loop Spinal Stimulation for Restoration of Upper Extremity Function After Spinal Cord Injury
RECRUITING · NA
-
Neuromodulation to Improve Respiratory Function in Cervical Spinal Cord Injury
RECRUITING · NA
-
Transcutaneous Spinal Stimulation and Exercise for Locomotion
RECRUITING · NA
-
HAPPINESS: cHAnging the Perceived Pain INtEnSity in Populations With Spinal Cord Injury and With Health Disparities: A Feasibility Study
RECRUITING · NA
-
Dosing rTMS for Depression Post-SCI
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00576069 · 60 participants
Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma
- NCT01297400 · 60 participants · Phase 2
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
- NCT01734122 · 60 participants
Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor
- NCT01804634 · 60 participants · Phase 2
Reduced Intensity Haploidentical BMT for High Risk Solid Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT06358040 · started 2026-10 · NA
Opioid Dispenser for Microdiscectomy/Laminectomy