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NCT06438471 · ClinicalTrials.gov registry record · Phase 1
Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury
A Phase 1 study of Spinal Cord Injuries and Degenerative Disc Disease, sponsored by EicOsis Human Health.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT06438471 is a Phase 1 study of Spinal Cord Injuries and Degenerative Disc Disease that is actively recruiting participants, run by EicOsis Human Health. The registered enrollment target is 36 participants, below the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (41% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06438471, a Phase 1 study of Spinal Cord Injuries and Degenerative Disc Disease, is actively recruiting participants, sponsored by EicOsis Human Health.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to evaluate safety and tolerability of multiple oral doses of EC5026 in male and female patients with neuropathic pain due to traumatic or non-traumatic (degenerative) spinal cord injury. The main question it aims to answer is whether EC5026 is safe and well tolerated in SCI patients with neuropathic pain. In addition, this trial will also study the effects of EC5026 on pain. Researchers will compare EC5026 to placebo. Participants will be asked to: * Take EC5026 or placebo in a masked fashion, once daily, for 14 consecutive days. * Undergo physical exams, vital signs assessments, ECGs, and blood draws * Complete assessments of pain, sleep, functional status, and perception of change
Conditions Studied
Interventions
- DRUG EC5026 oral tablet
- DRUG Placebo oral tablet
Study Locations (1)
Georgia
- AU Medical Center - Augusta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2026-02-28 |
| Est. Completion | 2027-06 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06438471
The ClinicalTrials.gov registry entry for NCT06438471 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (41% lower). The listed sponsor is EicOsis Human Health, which has 5 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Spinal Cord Injuries appearing as the primary indexed condition, and to 2 interventions - of which EC5026 oral tablet is the first listed.
NCT06438471 reports 1 study location spanning 1 distinct geographic area - top geographies include Georgia.
Frequently Asked Questions
What is clinical trial NCT06438471 about?
NCT06438471 is a clinical study titled "Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury". The goal of this clinical trial is to evaluate safety and tolerability of multiple oral doses of EC5026 in male and female patients with neuropathic pain due to traumatic or non-traumatic (degenerative) spinal cord injury. The main question it aims to answer is whether EC5026 is safe and well tolera...
What is the current status of trial NCT06438471?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2026-02-28. Estimated completion is 2027-06.
What conditions does trial NCT06438471 study?
This clinical trial studies the following conditions: Spinal Cord Injuries, Degenerative Disc Disease, Neuropathic Pain, Spinal Stenosis, Spondylosis.
What interventions are being tested in trial NCT06438471?
The interventions under investigation include: EC5026 oral tablet (DRUG), Placebo oral tablet (DRUG).
Who is sponsoring clinical trial NCT06438471?
This trial is sponsored by EicOsis Human Health, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06438471 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.