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NCT07064018 · ClinicalTrials.gov registry record · Phase 1

Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

A Phase 1 study of Non-Small Cell Lung Cancer and Ovarian Cancer, sponsored by University of California, Irvine.

Recruiting
Registry status
Phase 1
Development phase
67
Enrollment target
1
Study location

NCT07064018 is a Phase 1 study of Non-Small Cell Lung Cancer and Ovarian Cancer that is actively recruiting participants, run by University of California, Irvine. The registered enrollment target is 67 participants, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07064018, a Phase 1 study of Non-Small Cell Lung Cancer and Ovarian Cancer, is actively recruiting participants, sponsored by University of California, Irvine.

RECRUITING
Registry status
Phase 1
Development phase
67 participants
Enrollment target
1
Study location

Study Summary

This is a Phase 1b/IIa dose escalation clinical trial determining the recommended phase II dose of SPEDOX-6 in subjects with advanced, therapy-refractory soft-tissue sarcoma (STS); triple-negative breast cancer (TNBC); Non-small cell lung cancer (NSCLC); cervical cancer; ovarian cancer; KRAS mutant pancreatic ductal adenocarcinoma. These are subjects who have not previously been treated with anthracyclines.

Interventions

  • DRUG Filgrastim
  • DRUG Spedox-6
  • DRUG Pegfilgrastim

Study Locations (1)

California

  • Chao Family Comprehensive Cancer Center University of California, Irvine - Orange

Trial Details

FieldValue
Enrollment Target 67 participants
Start Date 2025-04-30
Est. Completion 2031-12-31
Phase Phase 1

Sponsor

University of California, Irvine

368 total trials

What the Registry Record Tells You About NCT07064018

The ClinicalTrials.gov registry entry for NCT07064018 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 67 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (90% lower). The listed sponsor is University of California, Irvine, which has 368 total studies on file at ClinicalTrials.gov.

The record links to 6 conditions, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 3 interventions - of which Filgrastim is the first listed.

NCT07064018 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT07064018 about?

NCT07064018 is a clinical study titled "Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies". This is a Phase 1b/IIa dose escalation clinical trial determining the recommended phase II dose of SPEDOX-6 in subjects with advanced, therapy-refractory soft-tissue sarcoma (STS); triple-negative breast cancer (TNBC); Non-small cell lung cancer (NSCLC); cervical cancer; ovarian cancer; KRAS mutant ...

What is the current status of trial NCT07064018?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 67 participants. The study started on 2025-04-30. Estimated completion is 2031-12-31.

What conditions does trial NCT07064018 study?

This clinical trial studies the following conditions: Non-Small Cell Lung Cancer, Ovarian Cancer, Cervical Cancer, Triple Negative Breast Cancer, Soft Tissue Sarcoma.

What interventions are being tested in trial NCT07064018?

The interventions under investigation include: Filgrastim (DRUG), Spedox-6 (DRUG), Pegfilgrastim (DRUG).

Who is sponsoring clinical trial NCT07064018?

This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07064018 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.