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RECRUITING Phase 1

A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors

NCT05989724 · View on ClinicalTrials.gov ↗

Study Summary

This proposed Phase I clinical trial of SON-DP is an FIH, open-label, Phase Ia/Ib dose escalation and expansion study to evaluate the safety, tolerability, PK, and PD of SON-DP in participants with relapsed/refractory/intolerant to standard of care therapies, for advanced/ metastatic solid tumors.

Interventions

  • DRUG SON-DP

Study Locations (5)

Arizona

  • Banner MD Anderson Cancer Center (BMDACC) — Gilbert

Michigan

  • Henry Ford Health System — Detroit

North Carolina

  • Carolina BioOncology Institute — Huntersville

Oklahoma

  • Stephenson Cancer Center, University of Oklahoma — Oklahoma City

Texas

  • MD Anderson Cancer Center — Houston

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2023-09-19
Est. Completion 2026-03
Phase Phase 1

Sponsor

Qurgen

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05989724

The ClinicalTrials.gov registry entry for NCT05989724 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Qurgen, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 5 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention — of which SON-DP is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05989724 reports 5 study locations spanning 5 distinct geographic areas — top geographies include Arizona, Michigan, North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05989724 about?

NCT05989724 is a clinical study titled "A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors". This proposed Phase I clinical trial of SON-DP is an FIH, open-label, Phase Ia/Ib dose escalation and expansion study to evaluate the safety, tolerability, PK, and PD of SON-DP in participants with relapsed/refractory/intolerant to standard of care therapies, for advanced/ metastatic solid tumors.

What is the current status of trial NCT05989724?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 150 participants. The study started on 2023-09-19. Estimated completion is 2026-03.

What conditions does trial NCT05989724 study?

This clinical trial studies the following conditions: Breast Cancer, Colorectal Cancer, Ovarian Cancer, Pancreatic Cancer, Solid Tumor. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05989724?

The interventions under investigation include: SON-DP (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05989724?

This trial is sponsored by Qurgen, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05989724 being conducted?

This trial has 5 study locations across Arizona, Michigan, North Carolina, Oklahoma, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial