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RECRUITING Phase 2

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

NCT07023627 · View on ClinicalTrials.gov ↗

Study Summary

This study will evaluate the safety and efficacy of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer (PROC) With Cyclin E1 Overexpression.

Conditions Studied

Interventions

  • DRUG INCB123667

Study Locations (20)

Florida

  • Florida Cancer Specialists & Research Institute — Fort Myers
  • Sylvester Comprehensive Cancer Center — Miami
  • Mount Sinai Comprehensive Cancer Center — Miami Beach
  • Florida Cancer Specialists & Research Institute — West Palm Beach

California

  • University of California, Los Angeles Medical Center — Los Angeles
  • Scripps Healthscripps Mercy Hospital Prebys Cancer Center — San Diego

Maryland

  • Greater Baltimore Medical Center — Baltimore
  • John Hopkins University-School of Medicine — Baltimore

Massachusetts

  • Massachusetts General Hospital — Boston
  • Umass Memorial Medical Center, Inc. — Worcester

Alabama

  • Usa Health Mitchell Cancer Institute — Mobile

Arkansas

  • Uams Winthrop P Rockefeller Cancer Institute — Little Rock

District of Columbia

  • Medstar Georgetown University Hospital — Washington D.C.

Georgia

  • Northeast Georgia Medical Center Gainesville — Gainesville

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2025-11-12
Est. Completion 2027-10-24
Phase Phase 2

Sponsor

Incyte Corporation

163 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07023627

The ClinicalTrials.gov registry entry for NCT07023627 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Incyte Corporation, which has 163 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Ovarian Cancer appearing as the primary indexed condition, and to 1 intervention — of which INCB123667 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07023627 reports 20 study locations spanning 14 distinct geographic areas — top geographies include Florida, California, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07023627 about?

NCT07023627 is a clinical study titled "A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression". This study will evaluate the safety and efficacy of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer (PROC) With Cyclin E1 Overexpression.

What is the current status of trial NCT07023627?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 160 participants. The study started on 2025-11-12. Estimated completion is 2027-10-24.

What conditions does trial NCT07023627 study?

This clinical trial studies the following conditions: Ovarian Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07023627?

The interventions under investigation include: INCB123667 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07023627?

This trial is sponsored by Incyte Corporation, which has 163 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07023627 being conducted?

This trial has 20 study locations across Alabama, Arkansas, California, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial