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NCT06771219 · ClinicalTrials.gov registry record · Phase 1
SLV-154 Treatment of Metastatic Solid Tumors
A Phase 1 study of Ovarian Cancer and Endometrial Cancer, sponsored by Solve Therapeutics.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 70
- Enrollment target
- 9
- Study locations
NCT06771219: Recruiting Phase 1 study of Ovarian Cancer and Endometrial Cancer, sponsored by Solve Therapeutics.
NCT06771219 is a Phase 1 study of Ovarian Cancer and Endometrial Cancer that is actively recruiting participants, run by Solve Therapeutics. The registered enrollment target is 70 participants, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (90% lower). The trial reports 9 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06771219, a Phase 1 study of Ovarian Cancer and Endometrial Cancer, is actively recruiting participants, sponsored by Solve Therapeutics.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 70 participants
- Enrollment target
- 9
- Study locations
Study Summary
This is a Phase 1 dose-escalation study evaluating the safety, pharmacokinetics, pharmacodynamics, immunogenicity, and efficacy of SLV-154 across a range of dose levels when administered to subjects with metastatic solid tumors.
Primary Outcome
Determination of the MTD (maximum tolerated dose) and/or RDR (recommended dosing regimen) for SLV-154.
Conditions Studied
Interventions
- DRUG SLV-154
Study Locations (9)
Texas
- MD Anderson Cancer Center - Houston
- Oncology Consultants - Houston
- Mays Cancer Center; University of Texas Health San Antonio - San Antonio
Washington
- University of Washington / Fred Hutchinson Cancer Center - Seattle
- Northwest Medical Specialties, PLLC - Tacoma
California
- Hoag Memorial Hospital Presbyterian - Newport Beach
Missouri
- Washington University - St Louis
New Jersey
- Astera Cancer Care - East Brunswick
New York
- Memorial Sloan Kettering Cancer Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2025-05-14 |
| Est. Completion | 2027-04 |
| Phase | Phase 1 |
What NCT06771219 shows while recruiting
NCT06771219 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (90% lower).
The record links to 10 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 1 intervention - of which SLV-154 is the first listed.
NCT06771219 lists 9 locations in 6 states (Texas, Washington, California).
Frequently Asked Questions
What is clinical trial NCT06771219 about?
NCT06771219 is a clinical study titled "SLV-154 Treatment of Metastatic Solid Tumors". This is a Phase 1 dose-escalation study evaluating the safety, pharmacokinetics, pharmacodynamics, immunogenicity, and efficacy of SLV-154 across a range of dose levels when administered to subjects with metastatic solid tumors.
What is the current status of trial NCT06771219?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 70 participants. The study started on 2025-05-14. Estimated completion is 2027-04.
What conditions does trial NCT06771219 study?
This clinical trial studies the following conditions: Ovarian Cancer, Endometrial Cancer, Sarcoma, NSCLC, Thyroid Cancer.
What interventions are being tested in trial NCT06771219?
The interventions under investigation include: SLV-154 (DRUG).
Who is sponsoring clinical trial NCT06771219?
This trial is sponsored by Solve Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06771219 being conducted?
This trial has 9 study locations across California, Missouri, New Jersey, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Ovarian Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06771219's enrollment target sits among peer trials
70 177th of 322 higher than 140 of 322 other Ovarian Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ovarian Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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