Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Obesity: early-phase trial registry
306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3 of 28,963 conditions by registered trial count.
1,057 US clinical trials · 306 currently recruiting · #3 of 28,963 conditions by registered trial count
Obesity: 1,057 US clinical trials tracked, 306 recruiting.
Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.
Open enrollment, early-phase tilt
Obesity has 1,057 registered US clinical trials, 306 of them open to new participants right now, about 29% of the total.
- 306
- recruiting participants now
- 29%
- of trials open to enrollment
- 107
- in Phase 3-4 (later-stage)
- 48
- top sponsor: Eli Lilly and Company
Corpus placement: #3 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.
Key findings
What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.
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Obesity is recruiting below its size-band peers.
306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obesity trials is spread across many organizations.
Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.
-
Typical Obesity enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.
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Obesity research is mostly interventional.
894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,057 total, page 20 of 22
Effect of Increased Free Fatty Acids on Leptin Function
Beth Israel Deaconess Medical Center
NCT01520454
Pilot Study: Identification of a Multi-omic Predictive Signature for Preterm Birth in Obese African American Women
Baylor University
NCT03181555
Qsymia as an Adjunct to Surgical Therapy in the Superobese
Wake Forest University Health Sciences
NCT02301416
Fruit And Vegetable Or Recreation Prescriptions for UW-Madison Students
University of Wisconsin, Madison
NCT02870322
Study Examining The Effect Of Hepatic Impairment On Safety, Toleration And How The Body Processes An Experimental Drug
Pfizer
NCT00645021
Pharmacodynamic Study of the Effect of INCB013739 on Insulin Sensitivity in Obese, Type 2 Diabetic Subjects
Incyte Corporation
NCT00478322
Fecal Microbiota Transplant for Improvement of Metabolism
Massachusetts General Hospital
NCT02530385
Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes
University of Colorado, Denver
NCT03620773
Carnitine and Liver Mitochondria Fatty Acid Processing
Pennington Biomedical Research Center
NCT03193125
Effects of Guided Exercise on Functional Performance and Independence in Adults With Intellectual Disability
University of Delaware
NCT04616638
Managing AsThma AnD Obesity Related Symptoms (MATADORS) Feasibility Study
Medical University of South Carolina
NCT05742646
Multivitamin Adherence Following Bariatric Surgery
Wake Forest University Health Sciences
NCT02124889
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of K-757 and K-833 in Overweight/Obese Patients With Type 2 Diabetes
Kallyope
NCT05890950
Pilot Trial of Naltrexone for Obesity in Women With Schizophrenia
Yale University
NCT00793780
Leisure Time Activity and Nutrition Program
The University of Tennessee, Knoxville
NCT00656045
Leptin in the Maintenance of Reduced Body Weight
Beth Israel Deaconess Medical Center
NCT01155180
mTORC1 and Autophagy in Human Brown Adipocytes
University of New Mexi
NCT04206124
The Physiologic Effects of Intranasal Oxytocin on Sarcopenic Obesity
Sara Espinoza
NCT03119610
Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness
Stanford University
NCT03935854
Resistance Training and Appetite Regulation
University of Colorado, Denver
NCT03985787
Serum and Tissue Cefazolin Concentrations in Patients Undergoing Cesarean Delivery
Michael Stitely
NCT01755026
Assessment of Endogenous Oxalate Synthesis
University of Alabama at Birmingham
NCT05229952
Feasibility or Oral Lactoferrin to Prevent Iron Deficiency Anemia in Obese Pregnancy
University of Illinois at Chicago
NCT04810546
Pathways Linking Reduced Sleep Duration and Quality to Obesity Risk
University of Chicago
NCT00915707
Nutrition and Soccer for Pediatric Overweight and Obesity
Leach Chiropractic Clinic
NCT00365651
Relation of Obesity With Frequency of Meals (MST 0557)
Rockefeller University
NCT00229255
Safety and Pharmacokinetics of Clindamycin in Pediatric Subjects With BMI ≥ 85th Percentile
Phillip Brian Smith
NCT01744730
The TREND Study: Tapered Reduction in Energy Intake as a Novel Approach to Dieting
Wake Forest University Health Sciences
NCT02837211
Metabolic and Cardiovascular Impact of CD36 Deficiency in African Americans
Vanderbilt University Medical Center
NCT02126735
Vasoprotective Activities of Low-Fat Milk in Individuals With Metabolic Syndrome
University of Connecticut
NCT01411293
Addressing Emotional and Cognitive Factors in Behavioral Weight Loss Treatment
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00533052
Appetite and Exercise in Breast Cancer Survivors
University of Colorado, Denver
NCT04300478
The Effect of Exercise on Hepatic Glucose Metabolism
Vanderbilt University
NCT01783275
The Effects Grapes on Health Indices
University of California, Davis
NCT01674231
Multimodel Exercise and Weight Loss in Older Obese Veterans With Dysmobility
VA Office of Research and Development
NCT02806336
Impact of Slowly Digestible Carbohydrates on the Gut-brain Axis
Purdue University
NCT05349903
Using Exhaled Air to Determine Changes in Nutritional Status of Patients on Intravenous Nutrition
University of Wisconsin, Madison
NCT02843256
Effect of Vestibular Stimulation on Fat Consumption and Energy Expenditure as Assessed Using Indirect Calorimetry
University of California, San Diego
NCT03138382
The DEB Pilot Study
Pennington Biomedical Research Center
NCT03190993
PRebiotic to IMprovE Calcium Absorption
San Francisco Veterans Affairs Medical Center
NCT03272542
Effect of Exenatide in Obese Patients With Accelerated Gastric Emptying
Mayo Clinic
NCT02160990
A Study to Compare Two Different Forms of PF-07081532 in Adults Who Are Overweight or Obese
Pfizer
NCT05677867
Mechanisms of Diabetes Control After Weight Loss Surgery
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00571220
High Fat Diet II on Weight Loss
Christiana Care Health Services
NCT00525850
Impact of a Childhood Obesity Intervention for African American Families
University of California, Berkeley
NCT02044731
Gut Microbiota Post Roux-en-Y Gastric Bypass Surgery
North Dakota State University
NCT02654496
A Study of a Values-Based Intervention to Promote Weight Loss
Drexel University
NCT03991676
Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents
Mayo Clinic
NCT01746264
Sex and Obesity: Effects on Heart Failure Study
Washington University School of Medicine
NCT00776035
Health At Every Size and Acceptance and Commitment Therapy vs. Behavioral Weight Loss for Obesity and Depression in Women
Dartmouth-Hitchcock Medical Center
NCT02501239
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 95 |
| Phase 2 | 101 |
| Phase 3 | 69 |
| Phase 4 | 38 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
What is open for Obesity right now
306 recruiting of 1,057 indexed (29% open).
Phase mix: 107 late (III/IV) vs 196 early (I/II) (early-phase heavy).
Top sponsor: Eli Lilly and Company (48 trials), 9 others listed. 50 shown below, recruiting first. #3 of 28,963 conditions by registered trial count.
How open-enrollment share is computed
Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.
Frequently Asked Questions
How many clinical trials are there for Obesity?
PlainTrial tracks 1,057 US clinical trials for Obesity, of which 306 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Obesity?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.