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NCT03272542 · ClinicalTrials.gov registry record · Phase 2
PRebiotic to IMprovE Calcium Absorption
A Phase 2 study of Obesity, sponsored by San Francisco Veterans Affairs Medical Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT03272542: Completed Phase 2 study of Obesity, sponsored by San Francisco Veterans Affairs Medical Center.
NCT03272542 is a Phase 2 study of Obesity that has completed, run by San Francisco Veterans Affairs Medical Center. The registered enrollment target is 20 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03272542, a Phase 2 study of Obesity, has completed, sponsored by San Francisco Veterans Affairs Medical Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Gastric bypass surgery is a highly effective treatment for obesity, but it has negative effects on skeletal health, due in part to a dramatic decline in intestinal calcium absorption capacity. Animal and human studies suggest that non-digestible fibers termed prebiotics, such as soluble corn fiber (SCF), augment calcium absorption in the lower intestine as they act as substrates for beneficial gut microbiota. This is a pilot randomized controlled trial of the effects of SCF vs. placebo on intestinal calcium absorption, bone turnover marker levels, and the gut microbiome in postmenopausal women who have previously undergone gastric bypass surgery.
Primary Outcome
Fractional calcium absorption to be determined using dual stable isotopic tracers
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Prebiotic: soluble corn fiber
- DIETARY_SUPPLEMENT Placebo: maltodextrin
Study Locations (1)
California
- UCSF - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2017-11-21 |
| Est. Completion | 2020-01-31 |
| Phase | Phase 2 |
What the finished NCT03272542 record still lists
NCT03272542 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Prebiotic: soluble corn fiber is the first listed.
NCT03272542 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT03272542 about?
NCT03272542 is a clinical study titled "PRebiotic to IMprovE Calcium Absorption". Gastric bypass surgery is a highly effective treatment for obesity, but it has negative effects on skeletal health, due in part to a dramatic decline in intestinal calcium absorption capacity. Animal and human studies suggest that non-digestible fibers termed prebiotics, such as soluble corn fiber (...
What is the current status of trial NCT03272542?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2017-11-21. Estimated completion is 2020-01-31.
What conditions does trial NCT03272542 study?
This clinical trial studies the following conditions: Obesity.
What interventions are being tested in trial NCT03272542?
The interventions under investigation include: Prebiotic: soluble corn fiber (DIETARY_SUPPLEMENT), Placebo: maltodextrin (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03272542?
This trial is sponsored by San Francisco Veterans Affairs Medical Center, which has 15 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03272542 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03272542's enrollment target sits among peer trials
20 946th of 1053 higher than 80 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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