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NCT01746264 · ClinicalTrials.gov registry record · Phase 1
Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents
A Phase 1 study of Obesity and Vitamin D Deficiency, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 19
- Enrollment target
- 1
- Study location
NCT01746264: Completed Phase 1 study of Obesity and Vitamin D Deficiency, sponsored by Mayo Clinic.
NCT01746264 is a Phase 1 study of Obesity and Vitamin D Deficiency that has completed, run by Mayo Clinic. The registered enrollment target is 19 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01746264, a Phase 1 study of Obesity and Vitamin D Deficiency, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 19 participants
- Enrollment target
- 1
- Study location
Study Summary
Vitamin D deficiency has been linked to endothelial dysfunction in adults. Obese adolescents have a high prevalence of Vitamin D deficiency as well as evidence of endothelial dysfunction. Our hypothesis is that supplementation of Vitamin D deficient adolescents with Vitamin D would lead to improvement in endothelial dysfunction.
Primary Outcome
Endothelial function was assessed by FMD, via a high-resolution Doppler ultrasonography examination of the right brachial artery. FMD was calculated as the maximal percentage increase in brachial artery diameter (BAD) from baseline after the release of cuff occlusion.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Vitamin D3
Study Locations (1)
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2012-11 |
| Est. Completion | 2013-12 |
| Phase | Phase 1 |
What the finished NCT01746264 record still lists
NCT01746264 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (98% lower).
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Vitamin D3 is the first listed.
NCT01746264 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT01746264 about?
NCT01746264 is a clinical study titled "Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents". Vitamin D deficiency has been linked to endothelial dysfunction in adults. Obese adolescents have a high prevalence of Vitamin D deficiency as well as evidence of endothelial dysfunction. Our hypothesis is that supplementation of Vitamin D deficient adolescents with Vitamin D would lead to improveme...
What is the current status of trial NCT01746264?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2012-11. Estimated completion is 2013-12.
What conditions does trial NCT01746264 study?
This clinical trial studies the following conditions: Obesity, Vitamin D Deficiency, Endothelial Dysfunction.
What interventions are being tested in trial NCT01746264?
The interventions under investigation include: Vitamin D3 (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01746264?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01746264 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01746264's enrollment target sits among peer trials
19 975th of 1053 higher than 73 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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