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Obesity: early-phase trial registry
306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3 of 28,707 conditions by registered trial count.
1,057 US clinical trials · 306 currently recruiting · #3 of 28,707 conditions by registered trial count
Obesity: 1,057 US clinical trials tracked, 306 recruiting.
Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.
Enrollment posture brief
Registry condition obesity
OPEN 306 | RECR 29% | LATE 107 | EARLY 196 | RANK #3 | SPON 48
Volume-matched condition peers
Nearest open-share peer: Metastatic Pancreatic Adenocarcinoma (29% recruiting · 38 trials)
Obesity lists 306 open slots (29% of 1,057 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Obesity is recruiting below its size-band peers.
306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obesity trials is spread across many organizations.
Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.
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Typical Obesity enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.
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Obesity research is mostly interventional.
894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,057 total, page 19 of 22
Supporting Together Exercise and Play and Improving Nutrition
Children's Hospital Medical Center, Cincinnati
NCT02724839
Effects of a Weight Reduction and Lifestyle Program in Older Adults
University of Pittsburgh
NCT00714506
CHOICES: Family Physicians Treat Overweight Children
University of Arizona
NCT01674920
Mitochondrial Function in Circulating Cells and Muscle Tissue
University of Arkansas
NCT02700698
Energy Balance Weight Regulation Study
National Center for Complementary and Integrative Health (NCCIH)
NCT00619008
Biological Effects of Weight Loss In Older, Obese Women
University of Florida
NCT01032733
Pathophysiology of Cardiometabolic Risk Factors in African Americans
Vanderbilt University Medical Center
NCT01122407
Topiramate in Adolescents With Severe Obesity
University of Minnesota
NCT01859013
Liraglutide (Saxenda(R)) in Adolescents With Obesity After Sleeve Gastrectomy
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT04883346
Skill-based Cooking Intervention to Reduce Eating Out
Children's Hospital Medical Center, Cincinnati
NCT02202733
Effect of Meal Number, Frequency, and Form on Satiety and Metabolism After Weight Loss Surgery
St. Luke's-Roosevelt Hospital Center
NCT01938469
A Mobile Intervention to Reduce Pain and Improve Health (MORPH)
Wake Forest University Health Sciences
NCT03377634
Engaging Patients in Weight Loss Tools
University of Florida
NCT04121312
Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers
Raziel Therapeutics
NCT03171415
Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention
Stanford University
NCT05715242
Gut Microbiota Changes in Obese Individuals Undergoing Dedicated Lifestyle Modification Programs
Mayo Clinic
NCT02855242
Does a Virtual Coach Offer a Better Solution for Weight Reduction in Ventral Hernia Patients With Obesity?
University of Florida
NCT05797974
A Drug-Drug Interaction (DDI) Study of LY3437943 in Obese Participants
Eli Lilly and Company
NCT05445232
Liking of Snack Foods - Sub-Study 1
The Miriam Hospital
NCT00200213
The Effects of Gum Chewing on Energy Intake and Expenditure
University of Wisconsin, Madison
NCT01043471
Contributing Factors in the Pathobiology of Airway Remodeling in Obesity
Duke University
NCT03115632
Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Specialist Treatment
Yale University
NCT03063606
A Family-Based Weight Loss Intervention for Youth With Intellectual Disability
University of Massachusetts, Boston
NCT02033642
Individualized Diet Improvement Program for Weight Loss and Maintenance, Cohort 2
University of Illinois at Urbana-Champaign
NCT04605640
Estrogen Sensitivity and Ovulatory Dysfunction in Obesity
University of Colorado, Denver
NCT01381016
Study of Impact of Behavioral Intervention- Exercise, Nutrition, Education- on Body Mass Index (BMI)
Steward St. Elizabeth's Medical Center of Boston
NCT00132132
Effects of Body Mass Index on the Hyperemic Response to Regadenoson
University of Utah
NCT00859833
Adolescent Gastric By-pass and Diabetic Precursors
Children's Hospital Medical Center, Cincinnati
NCT00360373
Partners in Health: A Couples-based Approach to Obesity Prevention
California Polytechnic State University-San Luis Obispo
NCT02205281
Translating the Diabetes Prevention Program Into a Virtual Lifestyle Management Program
University of Pittsburgh
NCT00867425
Evaluation of Muscle Activation Efficiency in Challenging Subjects
Niveus Medical
NCT01811446
Increased Dietary Protein and Meal Frequency Reduces Total and Abdominal Body Fat During Weight Maintenance and Weight Loss
Skidmore College
NCT01749449
Metabolic Fuels Study
Boston Children's Hospital
NCT02235038
Exendin-9,39 and Satiety After Bariatric Surgery
Mayo Clinic
NCT02779075
PK/PD of High Dose Pip/Tazo in Obese Patients
Loma Linda University
NCT01923363
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis
National Heart, Lung, and Blood Institute (NHLBI)
NCT04271735
Fish Oils and Adipose Inflammation Reduction
University of Pennsylvania
NCT02010359
Resveratrol and the Metabolic Syndrome
Rockefeller University
NCT01714102
Magnesium Supplementation in the Second Trimester of Pregnancy to Overweight and Obese Individuals
University of California, Los Angeles
NCT01510665
Inspiratory Muscle Training in Postmenopausal Women
Indiana University
NCT06459674
Engaging Men From Blue-collar Industries in Weight Loss
Rush University Medical Center
NCT05386238
Metabolic Effects of Betaine Supplementation
Joslin Diabetes Center
NCT01950039
Dopamine and Insulin Resistance
Vanderbilt University
NCT00802204
Mitochondrial Methylation in Type 2 Diabetes
University of Arizona
NCT04126551
Oral Amino Acid Nutrition to Improve Glucose Excursions in PCOS
University of Colorado, Denver
NCT03717935
Role Of Metabolic Adaptation In Weight Regain
Pennington Biomedical Research Center
NCT05766358
A Psychological and Behavioral Intervention for Post-Bariatric Patients
Mayo Clinic
NCT01453517
Impact of Almond Supplementation on Body Composition in Overweight/Obese Minority Adults
Columbia University
NCT02347007
TOPS for African American Breast Cancer Survivors
Duke University
NCT04741802
Development of PK/PD Model for Individualized Propofol Dosing
Children's Hospital Medical Center, Cincinnati
NCT00948597
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 95 |
| Phase 2 | 101 |
| Phase 3 | 69 |
| Phase 4 | 38 |
Top Sponsors
Named interventions
Most-linked intervention names on Obesity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Obesity trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Obesity page
1,057 registered trials, 306 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 306 Obesity trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eli Lilly and Company sponsors the most Obesity trials on record, review their full trial history before evaluating a specific study. See Eli Lilly and Company's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obesity condition card totals 1,057 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.