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NCT01923363 · ClinicalTrials.gov registry record · NA

PK/PD of High Dose Pip/Tazo in Obese Patients

A NA study of Obesity, sponsored by Loma Linda University.

Completed
Registry status
NA
Development phase
29
Enrollment target
1
Study location

NCT01923363 is a NA study of Obesity that has completed, run by Loma Linda University. The registered enrollment target is 29 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01923363, a NA study of Obesity, has completed, sponsored by Loma Linda University.

COMPLETED
Registry status
NA
Development phase
29 participants
Enrollment target
1
Study location

Study Summary

Worldwide rates of obesity have doubled in the last 30 years, and obesity has been associated as a risk factor for hospital-acquired infections and increased occurrence of death in critically-ill patients. Piperacillin/tazobactam is a commonly prescribed antibiotic for critically ill patients with an infection, however, limited information exists for dosing this drug in obese patients. In these limited reports, standard doses of piperacillin/tazobactam given to the small number of obese patients resulted in lower blood concentrations, which could lead to inadequate killing of bacteria. The purpose of this study is to compare blood concentrations from standard piperacillin/tazobactam dosing compared to higher dosing regimens in obese patients. This study will also include information on the safety and tolerability of the higher dose regimens. The study investigators believe that the higher dosing regimen will produce adequate blood levels in obese patients and will not add any more risk of harm to obese patients receiving this higher dose.

Conditions Studied

Interventions

  • DRUG Piperacillin/Tazobactam Standard Dose to High Dose

Study Locations (1)

California

  • Loma Linda University Medical Center - Loma Linda

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2014-02-25
Est. Completion 2016-01-23
Phase NA

Sponsor

Loma Linda University

237 total trials

What the Registry Record Tells You About NCT01923363

The ClinicalTrials.gov registry entry for NCT01923363 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (96% lower). The listed sponsor is Loma Linda University, which has 237 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Piperacillin/Tazobactam Standard Dose to High Dose is the first listed.

NCT01923363 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT01923363 about?

NCT01923363 is a clinical study titled "PK/PD of High Dose Pip/Tazo in Obese Patients". Worldwide rates of obesity have doubled in the last 30 years, and obesity has been associated as a risk factor for hospital-acquired infections and increased occurrence of death in critically-ill patients. Piperacillin/tazobactam is a commonly prescribed antibiotic for critically ill patients with a...

What is the current status of trial NCT01923363?

This trial is currently completed. It is a NA study. The enrollment target is 29 participants. The study started on 2014-02-25. Estimated completion is 2016-01-23.

What conditions does trial NCT01923363 study?

This clinical trial studies the following conditions: Obesity.

What interventions are being tested in trial NCT01923363?

The interventions under investigation include: Piperacillin/Tazobactam Standard Dose to High Dose (DRUG).

Who is sponsoring clinical trial NCT01923363?

This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01923363 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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