Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04126551 · ClinicalTrials.gov registry record
Mitochondrial Methylation in Type 2 Diabetes
A clinical trial of Obesity and Diabetes Mellitus, Type 2, sponsored by University of Arizona.
- Completed
- Registry status
- 27
- Enrollment target
- 1
- Study location
NCT04126551: Completed study of Obesity and Diabetes Mellitus, Type 2, sponsored by University of Arizona.
NCT04126551 is a study of Obesity and Diabetes Mellitus, Type 2 that has completed, run by University of Arizona. The registered enrollment target is 27 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04126551, a study of Obesity and Diabetes Mellitus, Type 2, has completed, sponsored by University of Arizona.
- COMPLETED
- Registry status
- 27 participants
- Enrollment target
- 1
- Study location
Study Summary
The overarching goal of this proposal is to determine whether DNA methylation of the mitochondrial DNA impairs mitochondrial function in insulin resistant states such as overweight/obesity and type 2 diabetes.
Primary Outcome
Mitochondrial DNA methylation and D-loop of mitochondria is altered in insulin resistant states such as overweight/obesity and type 2 diabetes
Conditions Studied
Interventions
- OTHER Methylation status
Study Locations (1)
Arizona
- Clinical and Translational Research Center (CaTS) - Tucson
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2019-07-23 |
| Est. Completion | 2023-12-31 |
What the finished NCT04126551 record still lists
NCT04126551 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (97% lower).
The record links to 4 conditions, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Methylation status is the first listed.
NCT04126551 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT04126551 about?
NCT04126551 is a clinical study titled "Mitochondrial Methylation in Type 2 Diabetes". The overarching goal of this proposal is to determine whether DNA methylation of the mitochondrial DNA impairs mitochondrial function in insulin resistant states such as overweight/obesity and type 2 diabetes.
What is the current status of trial NCT04126551?
This trial is currently completed. The enrollment target is 27 participants. The study started on 2019-07-23. Estimated completion is 2023-12-31.
What conditions does trial NCT04126551 study?
This clinical trial studies the following conditions: Obesity, Diabetes Mellitus, Type 2, Overweight, Insulin Resistance.
What interventions are being tested in trial NCT04126551?
The interventions under investigation include: Methylation status (OTHER).
Who is sponsoring clinical trial NCT04126551?
This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04126551 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04126551's enrollment target sits among peer trials
27 893rd of 1053 higher than 158 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
A Hip Flexion Feedback System for Exercise Monitoring in Individuals With Osteoarthritis and Obesity
RECRUITING · Phase 1
-
Metabolic Adaptations to Weight Loss With and Without Exercise
RECRUITING · NA
-
Testing an Integrated PTSD and Weight Management Intervention: A Hybrid Type 1 Trial
RECRUITING · NA
-
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation
RECRUITING · Phase 2
-
Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity
RECRUITING · Phase 2
-
Tai Chi as a Novel Strategy to Increase Physical Activity Among Adults Pursuing Metabolic and Bariatric Surgery
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00912041 · 27 participants · NA
BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia
- NCT02847559 · 27 participants · Phase 2
Optune Delivered Electric Field Therapy and Bevacizumab in Treating Patients With Recurrent or Progressive Grade 2 or 3 Meningioma
- NCT03380195 · 27 participants · NA
Effects of Watermelon Juice on Heart Rate Recovery and Post-exercise Muscle Soreness
- NCT03384238 · 27 participants · Phase 1
Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI