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NCT05766358 · ClinicalTrials.gov registry record
Role Of Metabolic Adaptation In Weight Regain
A clinical trial of Obesity and Weight Loss, sponsored by Pennington Biomedical Research Center.
- Completed
- Registry status
- 27
- Enrollment target
- 1
- Study location
NCT05766358 is a study of Obesity and Weight Loss that has completed, run by Pennington Biomedical Research Center. The registered enrollment target is 27 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05766358, a study of Obesity and Weight Loss, has completed, sponsored by Pennington Biomedical Research Center.
- COMPLETED
- Registry status
- 27 participants
- Enrollment target
- 1
- Study location
Study Summary
In a previous study (NCT04081337), 55 participants with obesity participated on a 18-week lifestyle intervention to reduce their body weight, targeting 10% body weight loss. The participants received tirzepatide (15mg after titration) or placebo during the weight loss intervention. Before and after the lifestyle intervention, energy expenditure (48-h room indirect calorimetry) and body weight and composition (dual-X-ray absorptiometry) were measured, thus enabling the assessment of metabolic adaptation. In this study, participants having provided their consent to be re-contacted will be invited to attend the research center 12,18 and 24 months after completing the lifestyle intervention. Body weight and composition will be measured, aiming to explore the association between metabolic adaptation and changes in body weight and composition after a weight loss intervention. In addition, we will explore whether weight and fat mass changes are different between groups, and whether these effects are mediated by metabolic adaptation.
Conditions Studied
Interventions
- DRUG Tirzepatide
- BEHAVIORAL Intensive lifestyle change therapy
Study Locations (1)
Louisiana
- Pennington Biomedical Research Center - Baton Rouge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2022-10-06 |
| Est. Completion | 2024-05-24 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05766358
The ClinicalTrials.gov registry entry for NCT05766358 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (97% lower). The listed sponsor is Pennington Biomedical Research Center, which has 258 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Tirzepatide is the first listed.
NCT05766358 reports 1 study location spanning 1 distinct geographic area - top geographies include Louisiana.
Frequently Asked Questions
What is clinical trial NCT05766358 about?
NCT05766358 is a clinical study titled "Role Of Metabolic Adaptation In Weight Regain". In a previous study (NCT04081337), 55 participants with obesity participated on a 18-week lifestyle intervention to reduce their body weight, targeting 10% body weight loss. The participants received tirzepatide (15mg after titration) or placebo during the weight loss intervention. Before and after ...
What is the current status of trial NCT05766358?
This trial is currently completed. The enrollment target is 27 participants. The study started on 2022-10-06. Estimated completion is 2024-05-24.
What conditions does trial NCT05766358 study?
This clinical trial studies the following conditions: Obesity, Weight Loss, Weight Gain.
What interventions are being tested in trial NCT05766358?
The interventions under investigation include: Tirzepatide (DRUG), Intensive lifestyle change therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT05766358?
This trial is sponsored by Pennington Biomedical Research Center, which has 258 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05766358 being conducted?
This trial has 1 study location across Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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