Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Obesity: early-phase trial registry
306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3 of 28,707 conditions by registered trial count.
1,057 US clinical trials · 306 currently recruiting · #3 of 28,707 conditions by registered trial count
Obesity: 1,057 US clinical trials tracked, 306 recruiting.
Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.
Enrollment posture brief
Registry condition obesity
OPEN 306 | RECR 29% | LATE 107 | EARLY 196 | RANK #3 | SPON 48
Volume-matched condition peers
Nearest open-share peer: Metastatic Pancreatic Adenocarcinoma (29% recruiting · 38 trials)
Obesity lists 306 open slots (29% of 1,057 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Obesity is recruiting below its size-band peers.
306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
Sponsorship of Obesity trials is spread across many organizations.
Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.
-
Typical Obesity enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.
-
Obesity research is mostly interventional.
894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,057 total, page 18 of 22
A Trial Investigating Safety, Tolerability, PK and PD for Multiple Doses of NNC9204-0530 in Male and Female Subjects Being Overweight or With Obesity
Novo Nordisk A/S
NCT02835235
Diet Composition and Cardiometabolic Risk Reduction in Adults With SCI
University of Alabama at Birmingham
NCT02630524
Reducing Dietary Energy Density by Incorporating Vegetables in Order to Decrease Energy Intake
Penn State University
NCT01165086
CO-OP Trial: Community-based Outreach on Obesity in Pregnancy
University of Missouri, Kansas City
NCT01841424
Virtual Lifestyle Medicine Comparative Effectiveness Research
Ohio University
NCT03731481
Targeting Body Image Among Women of Higher Body Weight
The Miriam Hospital
NCT04810247
Effect of GLP-1 Receptor Agonism After Sleeve Gastrectomy
Mayo Clinic
NCT03115424
T-helper 2 (Th2) Cytokine Responses in Overweight/Obese Subjects
West Penn Allegheny Health System
NCT02085759
Oral Contraceptives in the Metabolic Syndrome
Virginia Commonwealth University
NCT00205504
The Effect of the DASH Diet Containing Meat on Muscle and Metabolic Health in Older Adults
South Dakota State University
NCT04127240
ObeSity and Jobs in SoCioeconomically Disadvantaged CommUnities: A Randomized CLinical Precision Public HealTh Intervention --The SCULPT-Job Study
University of California, San Francisco
NCT04709549
Hybrid Argon Plasma Coagulation and Endoscopic Sleeve Gastroplasty Trial
Mayo Clinic
NCT05559866
Vitamin D Deficiency and Low Bone Mineral Content in Children
University of Massachusetts, Worcester
NCT00756899
Exercise and Pioglitazone for HIV-Metabolic Syndromes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00639457
Self-Monitoring Assessment in Real Time
University of South Carolina
NCT02868853
Reduced Carbohydrate Versus Fat in Obese Subjects
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00846040
Health Benefits of Chronic vs. Acute Exercise in Overweight Adults
University of Michigan
NCT01452087
Metabolic Parameters 3 Months, 9 Months, and 2 Years After Bariatric Surgery
The University of Texas Health Science Center, Houston
NCT00178633
Calcium, Dairy, and Body Fat in Adolescents
Purdue University
NCT00592137
Isocaloric Dietary Interventions for Insulin Resistance and the Metabolic Syndrome
Rockefeller University
NCT01040663
Fetuin-A Phosphorylation Status in Insulin Resistance and Metabolic Syndrome
Auburn University
NCT03478046
The Effect of Exenatide on Weight and Hunger in Obese, Healthy Women
Beth Israel Deaconess Medical Center
NCT00456885
The VALIDATE-D Study
Brigham and Women's Hospital
NCT01635062
Biology and Experience of Eating in Women With Obesity
University of California, San Francisco
NCT02805972
Behavioral Strategies for Weight Management
Stanford University
NCT00575731
Effects of Obesity and Physical Inactivity on Pregnancy Outcomes
Washington University School of Medicine
NCT02039414
Healthy Sleeping and Feeding During Infancy
Penn State University
NCT00125580
Effect of Vitamin D Supplementation on Inflammation and Cardiometabolic Risk Factors in Obese Adolescents
Stanford University
NCT01217840
Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics
University of Alabama at Birmingham
NCT04392284
IMPACT: Inactivity Monitoring and Physical Activity Controlled Trial
The University of Texas Medical Branch, Galveston
NCT01869348
Immunoglobulin G Therapy Dose Optimization
Rutgers, The State University of New Jersey
NCT04818177
Protein Source, Nutrition Messaging, and Food Intake
University of Arkansas, Fayetteville
NCT03083145
Energy Balance Interventions for Colorectal Cancer Prevention
Vanderbilt University
NCT00653484
Pilot Study of the Effect of Liraglutide on Weight Loss and Gastric Functions in Obesity
Mayo Clinic
NCT02647944
Effect of Whole-grape Powder on Body Composition, Fat and Bone Serum Biomarkers in Postmenopausal Women
Texas Woman's University
NCT01717820
Peer-delivered and Technology-Assisted Integrated Illness Management and Recovery
Dartmouth-Hitchcock Medical Center
NCT04481737
STEP AND GO: A Study of Technology-based Exercise Promotion
The University of Texas Medical Branch, Galveston
NCT01953224
Fruit and Vegetable Juice Concentrate Effects on RBP4 and Antioxidant Capacity in Lean and Overweight 6-10 Year Old Boys
Nemours Children's Clinic
NCT00842543
Examination of the Anti-inflammatory and Insulin Sensitizing Properties of Doxycycline in Humans
University of California, San Diego
NCT01375491
Feasibility Study of Receiving Feedback Messages Based on Self-monitored Dietary Intake
University of Pittsburgh
NCT02829632
Effects of Dietary Omega-3 Fatty Acids on Reproductive Hormones in Obese Women
University of Colorado, Denver
NCT01894581
Yoga Improves Aerobic Fitness, Glycemia and Mood State and Reduces Abdominal Obesity
Skidmore College
NCT02190136
Trial of Roflumilast in Asthma Management (TRIM)
Johns Hopkins University
NCT03532490
Noninvasive Neuromodulation of the Prefrontal Cortex in Subjects With Obesity
University of Sao Paulo
NCT02953353
A Default Option for Health: Improving Nutrition Within the Financial and Geographic Constraints of Food Insecurity
University at Albany
NCT04186533
The Effects of Pentoxifylline on PAI-1 in an Obese Population
Vanderbilt University
NCT00770328
The Beneficial Effects of Healthy Snacks on Appetite Control, Satiety, and Reward-driven Eating Behavior in Young People
University of Missouri-Columbia
NCT01781286
Does What You Eat Affect Your Brain
University of Washington
NCT05626907
Nutrition, Exercise, and Technology for Weight Loss
University of South Carolina
NCT02731768
Effect of Self Regulation With Mindfulness Training on Body Mass Index and Cardiovascular Risk Markers in Obese Adults
Mayo Clinic
NCT01375504
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 95 |
| Phase 2 | 101 |
| Phase 3 | 69 |
| Phase 4 | 38 |
Top Sponsors
Named interventions
Most-linked intervention names on Obesity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Obesity trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Obesity page
1,057 registered trials, 306 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 306 Obesity trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eli Lilly and Company sponsors the most Obesity trials on record, review their full trial history before evaluating a specific study. See Eli Lilly and Company's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obesity condition card totals 1,057 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.