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ClinicalTrials.gov 38 recruiting now official registry

Neuroblastoma clinical trials

38 of 98 indexed Neuroblastoma trials are currently recruiting.

98 US clinical trials · 38 currently recruiting

Neuroblastoma is the subject of 98 registered US clinical trials on ClinicalTrials.gov, 38 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 78 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 19 of these trials.

The research picture

Neuroblastoma has 98 registered US clinical trials, 38 of them open to new participants right now, about 39% of the total.

38
recruiting participants now
39%
of trials open to enrollment
6
in Phase 3–4 (later-stage)
19
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 148Phase 230Phase 36

Active & Recent Trials

98 total, page 2 of 2

ACTIVE NOT RECRUITING Early Phase 1 26 participants

A Study of N9 Chemotherapy in Children With Neuroblastoma

Memorial Sloan Kettering Cancer Center

NCT04947501

ACTIVE NOT RECRUITING Phase 1 26 participants

iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and Neuroblastoma

Baylor College of Medicine

NCT01953900

ACTIVE NOT RECRUITING Phase 1 24 participants

PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy

University of Florida

NCT04837547

ACTIVE NOT RECRUITING Early Phase 1 20 participants

An Investigational Scan (68Ga-DOTATATE PET/CT) in Diagnosing Pediatric Metastatic Neuroendocrine Tumors

Mayo Clinic

NCT04040088

ACTIVE NOT RECRUITING Phase 1 18 participants

Sorafenib and Cyclophosphamide/Topotecan in Patients With Relapsed and Refractory Neuroblastoma

New Approaches to Neuroblastoma Therapy Consortium

NCT02298348

ACTIVE NOT RECRUITING Phase 1 13 participants

Immunotherapy of Relapsed Refractory Neuroblastoma With Expanded NK Cells

New Approaches to Neuroblastoma Therapy Consortium

NCT02573896

ACTIVE NOT RECRUITING Early Phase 1 13 participants

18F-Fluorodopamine PET Studies of Neuroblastoma and Pheochromocytoma

St. Jude Children's Research Hospital

NCT03541720

ACTIVE NOT RECRUITING Phase 1 11 participants

Allogeneic Tumor Cell Vaccination With Oral Metronomic Cytoxan in Patients With High-Risk Neuroblastoma

Baylor College of Medicine

NCT01192555

ACTIVE NOT RECRUITING Phase 1 11 participants

3rd Generation GD-2 Chimeric Antigen Receptor and ICaspase Suicide Safety Switch, Neuroblastoma, GRAIN

Baylor College of Medicine

NCT01822652

ACTIVE NOT RECRUITING Phase 1 11 participants

Rapid Administration Pilot for Infusing Dinutuximab

Children's Hospital Los Angeles

NCT05421897

ACTIVE NOT RECRUITING NA 7 participants

PET Imaging of Solid Tumors Using 124I-Humanized 3F8: A Pilot Study

Memorial Sloan Kettering Cancer Center

NCT02307630

COMPLETED Phase 3 968 participants

Surgery in Treating Children With Neuroblastoma

Children's Oncology Group

NCT00003119

COMPLETED Phase 3 464 participants

Combination Chemotherapy and Surgery With or Without Isotretinoin in Treating Young Patients With Neuroblastoma

Children's Oncology Group

NCT00499616

COMPLETED Phase 3 198 participants

A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families

Tufts Medical Center

NCT00782145

COMPLETED Phase 2 164 participants

131 I-MIBG in Treating Patients With Refractory or Relapsed Neuroblastoma

University of California, San Francisco

NCT00293319

COMPLETED Phase 2 140 participants

Preventative Trial of Difluoromethylornithine (DFMO) in High Risk Patients With Neuroblastoma That is in Remission

Giselle Sholler

NCT02395666

COMPLETED Phase 2 122 participants

Impact of Ga-68 DOTATOC PET-CT Imaging in Management of Neuroendocrine Tumors

Sue O'Dorisio

NCT02441062

COMPLETED 121 participants

Prevalence+Significance of Paraneoplastic Autoantibodies in Many Cancers

Memorial Sloan Kettering Cancer Center

NCT00608452

COMPLETED 101 participants

iCAT for Recurrent/Refractory/HR Solid Tumors

Dana-Farber Cancer Institute

NCT01853345

COMPLETED Phase 2 90 participants

New Therapeutic Strategies for Patients With Ewing's Sarcoma Family of Tumors, High Risk Rhabdomyosarcoma, and Neuroblastoma

National Cancer Institute (NCI)

NCT00001335

COMPLETED Early Phase 1 78 participants

Local Control With Reduced-dose Radiotherapy for High-Risk Neuroblastoma

Memorial Sloan Kettering Cancer Center

NCT02245997

COMPLETED NA 69 participants

Anti-GD2 3F8 Monoclonal Antibody and GM-CSF for High-Risk Neuroblastoma

Memorial Sloan Kettering Cancer Center

NCT02100930

COMPLETED Phase 2 68 participants

Comparative Study of Sensitivity of Ga-DOTATOC PET vs Octreoscan SPECT + CT

Sue O'Dorisio

NCT01869725

COMPLETED Phase 1 54 participants

Study of MLN8237 in Combination With Irinotecan and Temozolomide

New Approaches to Neuroblastoma Therapy Consortium

NCT01601535

COMPLETED Phase 2 53 participants

Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant

Fred Hutchinson Cancer Center

NCT00410657

COMPLETED Phase 1 40 participants

Recombinant Human Thrombopoietin in Children Receiving Ifosfamide, Carboplatin, and Etoposide Chemotherapy

St. Jude Children's Research Hospital

NCT00187109

COMPLETED Phase 2 39 participants

3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Non-Myeloablative Therapy in Patients With High-Risk Neuroblastoma

Memorial Sloan Kettering Cancer Center

NCT01183429

COMPLETED Phase 2 39 participants

hu14.18-Interleukin-2 Fusion Protein in Treating Young Patients With Recurrent or Refractory Neuroblastoma

Children's Oncology Group

NCT00082758

COMPLETED Phase 2 34 participants

Campath-1H + FK506 and Methylprednisolone for GVHD

Case Comprehensive Cancer Center

NCT00109993

COMPLETED Phase 1 31 participants

N99-02: Melphalan and Buthionine Sulfoximine

New Approaches to Neuroblastoma Therapy Consortium

NCT00005835

COMPLETED Phase 2 30 participants

Rebeccamycin Analog in Treating Children With Relapsed or Refractory Neuroblastoma

Memorial Sloan Kettering Cancer Center

NCT00003737

COMPLETED Phase 1 30 participants

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Followed by Surgery and/or Radiation Therapy in Treating Young Patients With Advanced Neuroblastoma

Children's Oncology Group

NCT00002740

COMPLETED Phase 2 22 participants

Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT00024258

COMPLETED Phase 1 21 participants

Safety Study for Refractory or Relapsed Neuroblastoma With DFMO Alone and in Combination With Etoposide

Giselle Sholler

NCT01059071

COMPLETED Phase 1 21 participants

Zoledronic Acid (ZOMETA) With Cyclophosphamide With Neuroblastoma and Cortical Bone Involvement

Baylor College of Medicine

NCT00206388

COMPLETED Phase 1 19 participants

Blood T-Cells and EBV Specific CTLs Expressing GD-2 Specific Chimeric T Cell Receptors to Neuroblastoma Patients

Baylor College of Medicine

NCT00085930

COMPLETED Phase 1 19 participants

Decitabine Followed by a Cancer Antigen Vaccine for Patients With Neuroblastoma and Sarcoma

University of Louisville

NCT01241162

COMPLETED Phase 1 18 participants

HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors

Timothy Cripe

NCT00931931

COMPLETED Phase 1 17 participants

N2004-03: Intravenous Fenretinide in Treating Young Patients With Recurrent or Resistant Neuroblastoma

Nant Operations Center

NCT00646230

COMPLETED Phase 1 15 participants

A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors

National Cancer Institute (NCI)

NCT02107963

COMPLETED Phase 1 13 participants

Neuroblastoma Vaccine for Treatment of High-Risk Neuroblastoma After Chemotherapy

Malcolm Brenner

NCT00048386

COMPLETED Phase 2 9 participants

Cyclophosphamide, Topotecan, and Bevacizumab (CTB) in Patients With Relapsed/Refractory Ewing's Sarcoma and Neuroblastoma

Memorial Sloan Kettering Cancer Center

NCT01492673

COMPLETED Phase 1 9 participants

Using Gene Modified Neuroblastoma Cells for the Treatment of Relapsed/Refractory Neuroblastoma

Baylor College of Medicine

NCT00062855

COMPLETED Phase 2 4 participants

High-Dose 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Myeloablative Therapy and Autologous Stem-Cell Transplantation

Memorial Sloan Kettering Cancer Center

NCT01183416

COMPLETED Phase 2 3 participants

Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer

Roswell Park Cancer Institute

NCT00003661

COMPLETED Phase 1

Chemotherapy in Treating Children With Neuroblastoma

New Approaches to Neuroblastoma Therapy Consortium

NCT00002730

COMPLETED Phase 1

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

National Institutes of Health Clinical Center (CC)

NCT00064311

COMPLETED Phase 1

Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors

Indiana University School of Medicine

NCT00003107

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Phase Distribution

PhaseTrial count
Phase 1 48
Phase 2 30
Phase 3 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Neuroblastoma Trial Landscape

98 indexed Neuroblastoma studies · 38 recruiting (39%).

Phase mix: 6 late (III/IV) vs 78 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (19 trials), 9 others listed. 48 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Neuroblastoma?

PlainTrial tracks 98 US clinical trials for Neuroblastoma, of which 38 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Neuroblastoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.