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NCT00002740 · ClinicalTrials.gov registry record · Phase 1

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Followed by Surgery and/or Radiation Therapy in Treating Young Patients With Advanced Neuroblastoma

A Phase 1 study of Neuroblastoma, sponsored by Children's Oncology Group.

Completed
Registry status
Phase 1
Development phase
30
Enrollment target
7
Study locations

NCT00002740 is a Phase 1 study of Neuroblastoma that has completed, run by Children's Oncology Group. The registered enrollment target is 30 participants, below the 239-participant average among 94 other Neuroblastoma trials with a reported enrollment target (87% lower). The trial reports 7 study locations across 5 states.

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The verdict

NCT00002740, a Phase 1 study of Neuroblastoma, has completed, sponsored by Children's Oncology Group.

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target
7
Study locations

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy drugs and kill more tumor cells. Radiation therapy uses high-energy x-rays to damage tumor cells. PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy plus peripheral stem cell transplantation followed by surgery and/or radiation therapy in treating young patients who have newly diagnosed advanced neuroblastoma.

Conditions Studied

Neuroblastoma

Interventions

  • DRUG carboplatin
  • DRUG cyclophosphamide
  • DRUG etoposide
  • BIOLOGICAL filgrastim
  • DRUG doxorubicin hydrochloride

Study Locations (7)

California

  • Children's Hospital Los Angeles - Los Angeles
  • UCSF Cancer Center and Cancer Research Institute - San Francisco

Ohio

  • Children's Hospital Medical Center - Cincinnati - Cincinnati
  • Children's Hospital of Columbus - Columbus

Indiana

  • Indiana University Cancer Center - Indianapolis

Minnesota

  • University of Minnesota Cancer Center - Minneapolis

Washington

  • Children's Hospital and Regional Medical Center - Seattle - Seattle

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 1996-05
Est. Completion 2005-09
Phase Phase 1

Sponsor

Children's Oncology Group

342 total trials

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What the Registry Record Tells You About NCT00002740

The ClinicalTrials.gov registry entry for NCT00002740 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 239-participant average among 94 other Neuroblastoma trials with a reported enrollment target (87% lower). The listed sponsor is Children's Oncology Group, which has 342 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Neuroblastoma appearing as the primary indexed condition, and to 5 interventions - of which carboplatin is the first listed.

NCT00002740 reports 7 study locations spanning 5 distinct geographic areas - top geographies include California, Ohio, Indiana.

Frequently Asked Questions

What is clinical trial NCT00002740 about?

NCT00002740 is a clinical study titled "Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Followed by Surgery and/or Radiation Therapy in Treating Young Patients With Advanced Neuroblastoma". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy drugs and kill more tumor cells. Radiation therapy uses high-energy x-rays to damage tum...

What is the current status of trial NCT00002740?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 1996-05. Estimated completion is 2005-09.

What conditions does trial NCT00002740 study?

This clinical trial studies the following conditions: Neuroblastoma.

What interventions are being tested in trial NCT00002740?

The interventions under investigation include: carboplatin (DRUG), cyclophosphamide (DRUG), etoposide (DRUG), filgrastim (BIOLOGICAL), doxorubicin hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00002740?

This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00002740 being conducted?

This trial has 7 study locations across California, Indiana, Minnesota, Ohio, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.