Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 56 recruiting now official registry

Pregnancy Related clinical trials

Every US clinical trial registered for Pregnancy Related — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

100 US clinical trials · 56 currently recruiting

The research picture

Pregnancy Related has 100 registered US clinical trials, 56 of them open to new participants right now — about 56% of the total.

56
recruiting participants now
56%
of trials open to enrollment
9
in Phase 3–4 (later-stage)
4
top sponsor: University of Pittsburgh

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 100,000 participants

POWERMOM, A Healthy Pregnancy Research Community

Scripps Translational Science Institute

NCT03085875

RECRUITING NA 30,000 participants

Accountability for Care Through Undoing Racism & Equity for Moms

University of North Carolina, Chapel Hill

NCT05484804

RECRUITING 5,621 participants

An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis Exposed to Ruxolitinib Cream Versus Topical Corticosteroids During Pregnancy: A US Claims Database Analysis

Incyte Corporation

NCT06627335

RECRUITING 2,600 participants

The Heartland Study

Heartland Health Research Alliance

NCT05492708

RECRUITING 2,000 participants

Compliant Analysis of Patient Samples and Data

Sequenom

NCT04364503

RECRUITING 1,725 participants

Postpartum Ultrasound Evaluation to Assess Risk of Hemorrhage

Endeavor Health

NCT06898034

RECRUITING 1,329 participants

WAKIX® (Pitolisant) Pregnancy Registry

Harmony Biosciences Management

NCT05536011

RECRUITING NA 1,200 participants

Rigorous Evaluation of Yes and Know, a Fully Virtual Sexual Health and Well-Being Intervention for Youth

ETR Associates

NCT06581536

RECRUITING 1,150 participants

Understanding Practices of Lactation and Infant Feeding Together With Women With HIV in the United States

International Maternal Pediatric Adolescent AIDS Clinical Trials Group

NCT07293559

RECRUITING NA 1,125 participants

Effects of Systematic Cervical Exam Training on Labor and Delivery Care

Wake Forest University Health Sciences

NCT04421768

RECRUITING 1,000 participants

Maternal Autoimmune Disease Research Alliance (MADRA) Registry

Duke University

NCT03276923

RECRUITING 1,000 participants

Commercial or Open Source Closed Loop Impact on Pregnancy Study

University of California, San Francis

NCT06654713

RECRUITING 958 participants

Study to Compare Maternal, Fetal, and Infant Outcomes of Women With Mild to Moderate Atopic Dermatitis Exposed to Ruxolitinib Cream During Pregnancy With an Unexposed Control Population

Incyte Corporation

NCT06259669

RECRUITING 900 participants

Comparison of Two Salpingectomy Techniques for Sterilization at the Time of Cesarean Delivery

Inova Health Care Services

NCT06273683

RECRUITING 825 participants

PRospective Evaluation of Peripartum Anticoagulation ManaGement for ThrOmboembolism

University of Calgary

NCT05756244

RECRUITING 728 participants

Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring

Sumitomo Pharma Switzerland

NCT05739123

RECRUITING NA 576 participants

Well-Mama Community Doula Navigator Study

Northwestern University

NCT05179369

RECRUITING NA 540 participants

Trial of Community-based Patient Navigation

Emory University

NCT05588245

RECRUITING NA 432 participants

The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)

Temple University

NCT05499507

RECRUITING NA 430 participants

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)

Thomas Jefferson University

NCT06419803

RECRUITING NA 430 participants

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes

Thomas Jefferson University

NCT06419777

RECRUITING NA 412 participants

Building TrUst and UNiting Teams Through DouLa partnErship - BUNDLE

Medical College of Wisconsin

NCT05993689

RECRUITING NA 400 participants

Implementation of a Patient-centered, Reproductive Planning Decision Support Tool (MyPath) Among Women With Substance Use Disorder in the Immediate Postpartum Period

University of Pittsburgh

NCT04939012

RECRUITING NA 360 participants

Nourishing Tomorrow: Role of Medically Tailored Groceries in Addressing Food Insecurity During Pregnancy

Case Western Reserve University

NCT06965530

RECRUITING NA 268 participants

MAMA Tot - Healthy Weight Parallel Study

East Carolina University

NCT06598098

RECRUITING NA 242 participants

Substance Use Treatment and Access to Resources (STARS) Project

University of Oklahoma

NCT04459000

RECRUITING NA 204 participants

Patient Empowerment and Agency Through Intrapartum Counseling and Education

Oregon Health and Science University

NCT06787521

RECRUITING NA 200 participants

The Oklahoma Parent-Child Assistance Program

University of Oklahoma

NCT05534568

RECRUITING 200 participants

Safety Study for Prospective Assessment of Pregnancy Outcomes in Patients Treated With Tildrakizumab

Sun Pharmaceutical Industries Limited

NCT03992729

RECRUITING NA 176 participants

Mobile Application-based Exercise Intervention for Pregnant Women

Western Kentucky University

NCT05849649

RECRUITING Phase 2 150 participants

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

Cedars-Sinai Medical Center

NCT05552053

RECRUITING NA 150 participants

Better Lifestyle Counseling for African American Women During Pregnancy

University of Illinois at Chicago

NCT05234125

RECRUITING Phase 4 140 participants

Perineal Massage Using A Pelvic Wand During Pregnancy

Beth Israel Deaconess Medical Center

NCT06986824

RECRUITING NA 124 participants

Nourishing Beginnings: Addressing Food Insecurity During Pregnancy

Case Western Reserve University

NCT05341960

RECRUITING NA 108 participants

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

Boston University Charles River Campus

NCT05624931

RECRUITING 100 participants

Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

Ilana Hull

NCT05942313

RECRUITING NA 100 participants

Impact of Room Light on Uterine Contractions and Labor Progression in Pregnancy

Michigan State University

NCT04521972

RECRUITING 87 participants

Maternal Abdominal Morphology Assessment

University of Texas at Austin

NCT06784674

RECRUITING Phase 4 80 participants

Early Antenatal Support for Iron Deficiency Anemia

Thomas Jefferson University

NCT04278651

RECRUITING 60 participants

Physiological-based Pharmacokinetics Approach to Medication Exposure During Pregnancy and Breastfeeding

University of Pittsburgh

NCT05450978

RECRUITING 60 participants

Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy

Marshall University

NCT04755764

RECRUITING NA 60 participants

eDoula Feasibility and Acceptability

Oregon Health and Science University

NCT06785467

RECRUITING 60 participants

Observational Safety Study in Women With Neuromyelitis Optica Spectrum Disorder (NMOSD) Exposed to UPLIZNA® During Pregnancy

Amgen

NCT05909761

RECRUITING NA 60 participants

Community Translation of the Expecting Study

Arkansas Children's Hospital Research Institute

NCT04298125

RECRUITING NA 58 participants

Orthopaedic Manual Physical Therapy as Part of the Postpartum Care Continuum

Brooke Army Medical Center

NCT06560190

RECRUITING NA 55 participants

The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers

Rhode Island Hospital

NCT06737055

RECRUITING 50 participants

Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables

The Cleveland Clinic

NCT06818760

RECRUITING Phase 4 50 participants

Prophylactic Transfusion In Pregnant in Women With Sickle Cell Disease

Emory University

NCT06979492

RECRUITING 50 participants

The Effect of Fluids on Aortic VTI During C-section

Baylor College of Medicine

NCT04330742

RECRUITING NA 50 participants

A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures

Boston Children's Hospital

NCT06056635

RECRUITING NA 50 participants

Feasibility of a Prenatal Yoga Mobile App in African American Pregnant Women

San Diego State University

NCT06353113

RECRUITING NA 46 participants

Community-based Implementation of Adapted STAC

University of Wisconsin, Madison

NCT06689930

RECRUITING NA 40 participants

Myo-inositol During Pregnancy to Prevent Gestational Diabetes

Tufts Medical Center

NCT06575868

RECRUITING Phase 3 40 participants

Transdermal Patch for BupRenorphine Induction DurinG PrEgnancy (Patch BRIDGE)

Washington University School of Medicine

NCT05790252

RECRUITING 20 participants

Odevixibat Pregnancy and Lactation Surveillance Program: A Study to Evaluate the Safety of Odevixibat During Pregnancy and/or Lactation

Ipsen

NCT06258902

RECRUITING 20 participants

Mavacamten Pregnancy Surveillance Program

Bristol-Myers Squibb

NCT05939700

ACTIVE NOT RECRUITING 7,965 participants

Assessing the Safety of Pregnancy In the CoRonavirus (COVID-19) pandEmic

University of California, San Francis

NCT04388605

ACTIVE NOT RECRUITING NA 3,615 participants

Cash Benefits and Reproductive/Perinatal Health

Harvard Medical School (HMS and HSDM)

NCT05782660

ACTIVE NOT RECRUITING 2,500 participants

Health Disparities on the Labor Floor

University of Alabama at Birmingham

NCT04633824

ACTIVE NOT RECRUITING 2,179 participants

Glycemic Observation and Metabolic Outcomes in Mothers and Offspring

Northwestern University

NCT04860336

ACTIVE NOT RECRUITING NA 1,000 participants

STEPuP: Prenatal Provider Education and Training to Improve Medication-assisted Treatment Use During Pregnancy

University of Pittsburgh

NCT04527926

ACTIVE NOT RECRUITING Phase 3 788 participants

Natural Versus Programmed Frozen Embryo Transfer (NatPro)

JHSPH Center for Clinical Trials

NCT04551807

ACTIVE NOT RECRUITING NA 548 participants

The OPTIMIZE Study: Optimizing Patient Navigation for Perinatal Care

Northwestern University

NCT04261894

ACTIVE NOT RECRUITING 530 participants

MYFEMBREE®: A Retrospective Cohort Study Using an Administrative Healthcare Database to Assess Pregnancy Outcomes in Women Treated With Relugolix Combination Therapy

Sumitomo Pharma Switzerland

NCT05739136

ACTIVE NOT RECRUITING NA 416 participants

Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care

Washington University School of Medicine

NCT04838210

ACTIVE NOT RECRUITING 285 participants

Prospective Study of Pregnancy in Women With Cystic Fibrosis

Amalia Magaret

NCT04828382

ACTIVE NOT RECRUITING Phase 4 150 participants

Low Dose Aspirin for Preterm Preeclampsia Preventionmg/day Dose in High-risk Patients

University of Virginia

NCT05514847

ACTIVE NOT RECRUITING NA 135 participants

Maternal & Offspring Microbiome Study

Stanford University

NCT05123612

ACTIVE NOT RECRUITING 75 participants

The Heart Outcomes in Pregnancy Expectations (H.O.P.E) Registry

Saint Luke's Health System

NCT04828070

ACTIVE NOT RECRUITING 40 participants

Maternal Brain Imaging in Opioid Use Disorder

Indiana University

NCT06008990

ACTIVE NOT RECRUITING NA 35 participants

Healthier At-home Meals for Expectant Mothers

University of Alabama at Birmingham

NCT05605340

ACTIVE NOT RECRUITING Early Phase 1 26 participants

Open Trial of Technology-Enhanced Behavioral Intervention for Buprenorphine Retention in Pregnant and Postpartum People

Medical University of South Carolina

NCT06496230

ACTIVE NOT RECRUITING Phase 4 12 participants

Effects of Pregnancy-associated Hormones on THC Metabolism in Women

University of Washington

NCT04374773

ACTIVE NOT RECRUITING NA 10 participants

Continuous And Data-drivEN CarE (CADENCE) Pilot

University of South Florida

NCT05609669

COMPLETED 12,344 participants

Assessing the Effectiveness and Efficacy of the MyHealthyPregnancy Application

Naima Health

NCT05502510

COMPLETED 592 participants

Feasibility of Immediate Postpartum Long-acting Reversible Contraception Implementation

University of Michigan

NCT03774797

COMPLETED NA 451 participants

Healthy Moms: Prenatal Counseling for Postpartum Health

University of California, Davis

NCT04601987

COMPLETED NA 224 participants

Evaluation of Medicaid Food & Nutrition Support Program for Pregnant Women

University of Texas at Austin

NCT06368739

COMPLETED NA 216 participants

Father Inclusive Prenatal Care Study

Rush University Medical Center

NCT05652387

COMPLETED NA 201 participants

LaPPS: Labor Podcast for Patient Satisfaction

University of Pennsylvania

NCT04933708

COMPLETED Phase 4 180 participants

Misoprostol Dosing in BMI Greater Than 30

University of Texas at Austin

NCT05262738

COMPLETED Phase 3 140 participants

Medication Treatment for Opioid Use Disorder in Expectant Mothers

T. John Winhusen, PhD

NCT03918850

COMPLETED 97 participants

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study

T. John Winhusen, PhD

NCT03911466

COMPLETED NA 74 participants

Video Counseling: A Randomized Control Trial

University of Louisville

NCT04300725

COMPLETED 71 participants

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study

T. John Winhusen, PhD

NCT03911739

COMPLETED NA 62 participants

Deep Breathing Techniques (Pranayama) in Pregnancy

Children's Mercy Hospital Kansas City

NCT05341921

COMPLETED NA 56 participants

Daily Meditation Program in Women Admitted to the Antepartum Unit

The University of Texas Health Science Center, Houston

NCT03737279

COMPLETED NA 54 participants

Digital Intervention To Improve Diet Quality

Duke University

NCT04098016

COMPLETED NA 53 participants

A Clinical Study to Investigate the Reliability of Fetal Heart Rate and Maternal Heart Rate Signals Extracted From Biopotential Data

Bloom Technologies

NCT05498298

COMPLETED NA 52 participants

Research on Improving Sleep During Pregnancy

University of California, San Francis

NCT05017974

COMPLETED NA 50 participants

Piloting JUN_Pregnancy Mobile Medical App

The University of Texas Health Science Center at San Antonio

NCT06636110

COMPLETED NA 36 participants

INcreasing Steps in PREgnancy Study

University of Iowa

NCT05455008

COMPLETED NA 32 participants

Pilot Trial of Using SmokeBeat to Monitor and Increase Smoking Abstinence in Pregnant Women

University of Pennsylvania

NCT03209557

COMPLETED NA 31 participants

Online Intervention to Promote Resilience to Traumatic Stress During Pregnancy

University of Illinois at Chicago

NCT04992767

COMPLETED 30 participants

Medications in Breast Milk: A Convenience Pharmacokinetic Study

Indiana University

NCT05099484

COMPLETED NA 26 participants

Motivational Interviewing for Getting Healthy TodaY Study

Columbia University

NCT03410225

COMPLETED Early Phase 1 25 participants

Inpatient Adolescent Contraception

Children's Mercy Hospital Kansas City

NCT04423068

COMPLETED 13 participants

Quantitative Sensory Psychophysical Correlates of Pain in Pregnant Women With OUD

University of Pittsburgh

NCT04888962

COMPLETED NA 12 participants

Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) During Pregnancy

Penn State University

NCT05822531

COMPLETED NA 6 participants

An mHealth Intervention for Sedentary Behavior in Pregnant Women

University of South Carolina

NCT04903574

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 1
Phase 3 3
Phase 4 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pregnancy Related Trial Landscape

ClinicalTrials.gov lists 100 US studies indexed under Pregnancy Related, and 56 of those are currently open to recruitment — roughly 56% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Pregnancy Related shows 9 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Pregnancy Related is led by University of Pittsburgh with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pregnancy Related?

PlainTrial tracks 100 US clinical trials for Pregnancy Related, of which 56 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pregnancy Related?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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