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NCT00002730 · ClinicalTrials.gov registry record · Phase 1
Chemotherapy in Treating Children With Neuroblastoma
A Phase 1 study of Neuroblastoma, sponsored by New Approaches to Neuroblastoma Therapy Consortium.
- Completed
- Registry status
- Phase 1
- Development phase
- 4
- Study locations
NCT00002730: Completed Phase 1 study of Neuroblastoma, sponsored by New Approaches to Neuroblastoma Therapy Consortium.
NCT00002730 is a Phase 1 study of Neuroblastoma that has completed, run by New Approaches to Neuroblastoma Therapy Consortium. The trial reports 4 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00002730, a Phase 1 study of Neuroblastoma, has completed, sponsored by New Approaches to Neuroblastoma Therapy Consortium.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 4
- Study locations
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Some tumors become resistant to chemotherapy drugs. Combining buthionine sulfoximine with chemotherapy may reduce resistance to the drug and allow more tumor cells to be killed. PURPOSE: Phase I trial to study the effectiveness of melphalan, buthionine sulfoximine, and G-CSF in treating children with progressive neuroblastoma that has not responded to previous therapy.
Conditions Studied
Interventions
- DRUG melphalan
- DRUG buthionine sulfoximine
Study Locations (4)
California
- Children's Hospital Los Angeles - Los Angeles
- UCSF Cancer Center and Cancer Research Institute - San Francisco
Minnesota
- University of Minnesota Cancer Center - Minneapolis
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Start Date | 1996-06 |
| Phase | Phase 1 |
What the finished NCT00002730 record still lists
NCT00002730 is an interventional study that assigns participants to a tested intervention. An enrollment target was not published in the registry record, which is common for early-stage or observational entries.
The record links to 1 condition, with Neuroblastoma appearing as the primary indexed condition, and to 2 interventions - of which melphalan is the first listed.
NCT00002730 reports a single indexed study location in California, Minnesota, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00002730 about?
NCT00002730 is a clinical study titled "Chemotherapy in Treating Children With Neuroblastoma". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Some tumors become resistant to chemotherapy drugs. Combining buthionine sulfoximine with chemotherapy may reduce resistance to the drug and allow more tumor cells to be killed. P...
What is the current status of trial NCT00002730?
This trial is currently completed. It is a Phase 1 study. The study started on 1996-06.
What conditions does trial NCT00002730 study?
This clinical trial studies the following conditions: Neuroblastoma.
What interventions are being tested in trial NCT00002730?
The interventions under investigation include: melphalan (DRUG), buthionine sulfoximine (DRUG).
Who is sponsoring clinical trial NCT00002730?
This trial is sponsored by New Approaches to Neuroblastoma Therapy Consortium, which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00002730 being conducted?
This trial has 4 study locations across California, Minnesota, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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