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NCT01183416 · ClinicalTrials.gov registry record · Phase 2

High-Dose 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Myeloablative Therapy and Autologous Stem-Cell Transplantation

A Phase 2 study of Neuroblastoma, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
Phase 2
Development phase
4
Enrollment target
1
Study location

NCT01183416 is a Phase 2 study of Neuroblastoma that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 4 participants, below the 239-participant average among 94 other Neuroblastoma trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01183416, a Phase 2 study of Neuroblastoma, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
4 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to see if high-dose 3F8 combined with GM-CSF is better than standard dose 3F8 in treating neuroblastoma. Another purpose of the study is to find out what effects, good and/or bad, 3F8 has on cancer. The investigators also want to see if the antibody works against a very small amount of neuroblastoma (minimal residual disease) that is left in the bone marrow.

Conditions Studied

Interventions

  • DRUG 3F8 monoclonal antibody and 13-cis-Retinoic Acid

Study Locations (1)

New York

  • Memorial Sloan-Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2010-08
Est. Completion 2018-10-31
Phase Phase 2

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT01183416

The ClinicalTrials.gov registry entry for NCT01183416 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 239-participant average among 94 other Neuroblastoma trials with a reported enrollment target (98% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Neuroblastoma appearing as the primary indexed condition, and to 1 intervention - of which 3F8 monoclonal antibody and 13-cis-Retinoic Acid is the first listed.

NCT01183416 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT01183416 about?

NCT01183416 is a clinical study titled "High-Dose 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Myeloablative Therapy and Autologous Stem-Cell Transplantation". The purpose of this study is to see if high-dose 3F8 combined with GM-CSF is better than standard dose 3F8 in treating neuroblastoma. Another purpose of the study is to find out what effects, good and/or bad, 3F8 has on cancer. The investigators also want to see if the antibody works against a very ...

What is the current status of trial NCT01183416?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2010-08. Estimated completion is 2018-10-31.

What conditions does trial NCT01183416 study?

This clinical trial studies the following conditions: Neuroblastoma.

What interventions are being tested in trial NCT01183416?

The interventions under investigation include: 3F8 monoclonal antibody and 13-cis-Retinoic Acid (DRUG).

Who is sponsoring clinical trial NCT01183416?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01183416 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.