Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Menopause: full-pipeline trial registry
18 of 55 indexed Menopause trials are currently recruiting.
Corpus placement: #254 of 28,707 conditions by registered trial count.
55 US clinical trials · 18 currently recruiting · #254 of 28,707 conditions by registered trial count
Menopause: 55 US clinical trials tracked, 18 recruiting.
Menopause is the subject of 55 registered US clinical trials on ClinicalTrials.gov, 18 of them currently open to new participants. 12 are in Phase 3-4 (later-stage) and 17 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 6 of these trials.
Enrollment posture brief
Registry condition menopause
OPEN 18 | RECR 33% | LATE 12 | EARLY 17 | RANK #254 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Non-alcoholic Fatty Liver Disease (33% recruiting · 58 trials)
Menopause lists 18 open slots (33% of 55 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Menopause on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Menopause is recruiting below its size-band peers.
18 of 55 indexed trials (32.7%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Menopause trials is spread across many organizations.
University of Colorado, Denver accounts for 6 of 55 trials (10.9%). 38 distinct sponsors appear on at least one study for this condition label.
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Most Menopause trials plan to enrol fewer than 100 people.
Median target enrolment is 66 among the 55 trials that report a genuine target (sentinel values excluded). 33 of those (60%) plan for fewer than 100 participants.
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Menopause research is mostly interventional.
49 interventional and 6 observational studies make up this index (89.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
55 total, page 1 of 2
Apple Women's Health Study
Apple
NCT04196595
Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women
University of Minnesota
NCT04439370
Hot Flashes and Neurovascular Function in Women
Mayo Clinic
NCT05193968
Effects of Hemp-Derived Cannabinoids on Menopause Symptoms
Washington State University
NCT07393672
Cardiometabolic Consequences of the Loss of Ovarian Function
University of Colorado, Denver
NCT06264882
Impact of Cannabinoids on Menopause Symptoms
Washington State University
NCT06831916
Menopause Transition, Sex Hormone Deficiency and Autonomic and Vascular Function
University of Minnesota
NCT06490146
Sympathetic Vascular Transduction Across the Menopause Transition: Contributing Mechanisms
University of Missouri-Columbia
NCT06787066
Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia
University of Missouri-Columbia
NCT06417177
Efficacy of Suvorexant in the Treatment of Insomnia in Midlife Women With Pre-Diabetes
Brigham and Women's Hospital
NCT05593653
The Cardiovascular Impact of Hot Flushes
University of Minnesota
NCT05251324
Efficacy and Safety of Shatavari for Treatment of Menopausal Symptoms in Women: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study
SF Research Institute
NCT06716554
Exercise Training Intensity and Nitrate Supplementation in Post-Menopausal Females
University of Virginia
NCT06480695
Improving Sympathetic Activity, Hot Flashes, and Sleep in Midlife Women Using Inspiratory Muscle Strength Training
Mayo Clinic
NCT06743269
The Anabolic Effect of Testosterone on Pelvic Floor Muscles
Brigham and Women's Hospital
NCT06111209
Depression, Aging, Stress and Heart Health Study
University of North Carolina, Chapel Hill
NCT05570721
Role of Menopause in Thermoregulation
Penn State University
NCT06798571
Choline Dose Ranging in Postmenopausal Women
Julie Dumas
NCT06924541
PhytoSERM to Prevent Menopause Associated Decline in Brain Metabolism and Cognition
Roberta Brinton
NCT05664477
Ovarian Hormone Regulation of Central and Cerebrovascular Hemodynamics (NoMEN Study)
University of Colorado, Denver
NCT05057546
MitoQ and Exercise Effects on Vascular Health
University of Colorado, Denver
NCT05686967
A Safety and Efficacy Study of the Combination Estradiol and Progesterone to Treat Vasomotor Symptoms
TherapeuticsMD
NCT01942668
Radicle Revive 24: A Study of Health and Wellness Products on Menopausal Health and Related Health Outcomes
Radicle Science
NCT06749288
Study of the Safety and Efficacy of Desvenlafaxine Succinate for Vasomotor Symptoms in Postmenopausal Women
Wyeth is now a wholly owned subsidiary of Pfizer
NCT00369434
MyMenoPlan: Online Resource for Improving Women's Menopause Knowledge and Informed Decision-making
University of California, San Diego
NCT05299983
MsFLASH-02: Interventions for Relief of Menopausal Symptoms: A 3-by-2 Factorial Design Examining Yoga, Exercise, and Omega-3 Supplementation
Fred Hutchinson Cancer Center
NCT01178892
Study of the Efficacy of ESTRATEST® H.S. Tablets in Relieving Menopausal Symptoms in Estrogenized Postmenopausal Women
Solvay Pharmaceuticals
NCT00141570
A Safety and Efficacy Study of Estradiol Vaginal Capsule in Postmenopausal Women With Vulvovaginal Atrophy
Warner Chilcott
NCT02670785
Perimenopausal Estrogen Replacement Therapy Study
University of North Carolina, Chapel Hill
NCT01308814
Behavioral Treatment of Menopausal Insomnia; Sleep and Daytime Outcomes
Christopher Drake
NCT01933295
Development and Evaluation of a Hormone Replacement Therapy Decision-Aid
US Department of Veterans Affairs
NCT00012909
Caria: Digital Intervention for Menopause Symptom
University of Illinois at Chicago
NCT04882982
Hormone Replacement in Menopausal Women With Epilepsy
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00027209
Use of Black Cohosh and Red Clover for the Relief of Menopausal Symptoms
National Center for Complementary and Integrative Health (NCCIH)
NCT00066144
FP-101 Versus Placebo in the Treatment of Menopausal Vasomotor Symptoms
Fervent Pharmaceuticals
NCT05312567
Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women
University of Colorado, Denver
NCT02042196
Research Investigation of Soy and Estrogen
University of Illinois at Chicago
NCT00997893
Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure
National Eye Institute (NEI)
NCT00471731
Metabolic and Psychological Changes Associated With Menopause Among Women With HIV
Massachusetts General Hospital
NCT01142817
Hormone Estradiol Replacement Therapy Additional Herbals
Trieu, Nguyen Thi, M.D.
NCT02618148
Following Lipectomy to Understand Adipose Tissue Re-accumulation
University of Colorado, Denver
NCT00995631
Effects of Tibilone on Bone Density, Menopause Symptoms and Breast Density in Women After Prophylactic Oophorectomy
Dana-Farber Cancer Institute
NCT00165204
Therapy to Prevent Sexual Pain in Breast Cancer Survivors
OHSU Knight Cancer Institute
NCT01539317
Estrogen Variability and Irritability During the Menopause Transition
University of North Carolina, Chapel Hill
NCT05388656
Pilot Study of Stellate Ganglion Injection to Provide Relief From Hot Flushes
Northwestern University
NCT00992914
Reducing the Experience of Menopausal Symptoms Through Temperature
Wake Forest University Health Sciences
NCT03937466
The Role of the Gut Microbiota in Estrogen Metabolism and Dietary Flax as a Potential Modulator.
Colorado State University
NCT03183102
Duloxetine for Menopausal Depression
Massachusetts General Hospital
NCT01117857
Effect of Nuvigil on Fatigue
Massachusetts General Hospital
NCT01460628
A TSEC for Symptom Management in Menopausal Women With Multiple Sclerosis
University of California, San Francisco
NCT02710214
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 13 |
| Phase 3 | 3 |
| Phase 4 | 9 |
Top Sponsors
Named interventions
Most-linked intervention names on Menopause records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Menopause trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Menopause page
55 registered trials, 18 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 18 Menopause trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Colorado, Denver sponsors the most Menopause trials on record, review their full trial history before evaluating a specific study. See University of Colorado, Denver's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Menopause condition card totals 55 registered trials; most-linked intervention Placebo; top US site state Colorado. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.