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COMPLETED Phase 2

Use of Black Cohosh and Red Clover for the Relief of Menopausal Symptoms

NCT00066144 · View on ClinicalTrials.gov ↗

Study Summary

This Phase II study, a follow-up to a Phase I trial in normal volunteers, will determine the efficacy of black cohosh and red clover for the relief of menopausal symptoms. It will also assess the safety of chronic dosing (1 year) by evaluating uterine (endometrial biopsies), breast (mammography), and hematology parameters (CBC and chemistry lab values) at baseline and 1 year.

Conditions Studied

Interventions

  • DRUG Cimicifuga racemosa
  • DRUG Trifolium pratense
  • DRUG Black cohosh
  • DRUG Red clover

Study Locations (1)

Illinois

  • University of Illinois at Chicago — Chicago

Trial Details

FieldValue
Enrollment Target 112 participants
Start Date 2003-04
Est. Completion 2006-04
Phase Phase 2

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00066144

The ClinicalTrials.gov registry entry for NCT00066144 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 112 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Center for Complementary and Integrative Health (NCCIH), which has 55 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Menopause appearing as the primary indexed condition, and to 4 interventions — of which Cimicifuga racemosa is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00066144 reports 1 study location spanning 1 distinct geographic area — top geographies include Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00066144 about?

NCT00066144 is a clinical study titled "Use of Black Cohosh and Red Clover for the Relief of Menopausal Symptoms". This Phase II study, a follow-up to a Phase I trial in normal volunteers, will determine the efficacy of black cohosh and red clover for the relief of menopausal symptoms. It will also assess the safety of chronic dosing (1 year) by evaluating uterine (endometrial biopsies), breast (mammography), an...

What is the current status of trial NCT00066144?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 112 participants. The study started on 2003-04. Estimated completion is 2006-04.

What conditions does trial NCT00066144 study?

This clinical trial studies the following conditions: Menopause, Hot Flashes. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00066144?

The interventions under investigation include: Cimicifuga racemosa (DRUG), Trifolium pratense (DRUG), Black cohosh (DRUG), Red clover (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00066144?

This trial is sponsored by National Center for Complementary and Integrative Health (NCCIH), which has 55 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00066144 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial