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NCT00995631 · ClinicalTrials.gov registry record · NA

Following Lipectomy to Understand Adipose Tissue Re-accumulation

A NA study of Menopause and Pre-menopause, sponsored by University of Colorado, Denver.

Completed
Registry status
NA
Development phase
53
Enrollment target
1
Study location

NCT00995631 is a NA study of Menopause and Pre-menopause that has completed, run by University of Colorado, Denver. The registered enrollment target is 53 participants, below the 9,393-participant average among 54 other Menopause trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00995631, a NA study of Menopause and Pre-menopause, has completed, sponsored by University of Colorado, Denver.

COMPLETED
Registry status
NA
Development phase
53 participants
Enrollment target
1
Study location

Study Summary

The typical female pattern of accumulating fat in the hips and thighs has long been thought to confer less risk for disease than the typical male abdominal fat pattern. However, leg fat may not simply be benign with respect to disease risk, but may in fact protect against cardiovascular disease risk. Although the mechanism for this is unknown, the investigators hypothesize that removing a portion of this important fat depot (via liposuction) could increase disease risk. Such unfavorable results may or may not be transient depending on an individual's ability to defend their fat mass. Because sex hormones appear to play a role in regional fat accumulation, the investigators hypothesize that estrogen-deficient postmenopausal women may have an augmented abdominal fat accumulation and an attenuated hip and thigh re-accumulation compared to premenopausal women following lipectomy and compared to non-surgical controls. As a result, the increased abdominal fat accumulation may worsen disease risk in postmenopausal women. Menopause-related differences in fat storage at baseline are also expected to determine the degree to which lipectomy alters disease risk and the propensity for AT re-accumulation.

Conditions Studied

Interventions

  • PROCEDURE Femoral lipectomy

Study Locations (1)

Colorado

  • University of Colorado Anschutz Medical Campus - Aurora

Trial Details

FieldValue
Enrollment Target 53 participants
Start Date 2008-01
Est. Completion 2014-12
Phase NA

Sponsor

University of Colorado, Denver

1,283 total trials

What the Registry Record Tells You About NCT00995631

The ClinicalTrials.gov registry entry for NCT00995631 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 53 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 9,393-participant average among 54 other Menopause trials with a reported enrollment target (99% lower). The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Menopause appearing as the primary indexed condition, and to 1 intervention - of which Femoral lipectomy is the first listed.

NCT00995631 reports 1 study location spanning 1 distinct geographic area - top geographies include Colorado.

Frequently Asked Questions

What is clinical trial NCT00995631 about?

NCT00995631 is a clinical study titled "Following Lipectomy to Understand Adipose Tissue Re-accumulation". The typical female pattern of accumulating fat in the hips and thighs has long been thought to confer less risk for disease than the typical male abdominal fat pattern. However, leg fat may not simply be benign with respect to disease risk, but may in fact protect against cardiovascular disease risk...

What is the current status of trial NCT00995631?

This trial is currently completed. It is a NA study. The enrollment target is 53 participants. The study started on 2008-01. Estimated completion is 2014-12.

What conditions does trial NCT00995631 study?

This clinical trial studies the following conditions: Menopause, Pre-menopause.

What interventions are being tested in trial NCT00995631?

The interventions under investigation include: Femoral lipectomy (PROCEDURE).

Who is sponsoring clinical trial NCT00995631?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00995631 being conducted?

This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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