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ClinicalTrials.gov 51 recruiting now official registry

Leukemia clinical trials

51 of 274 indexed Leukemia trials are currently recruiting.

274 US clinical trials · 51 currently recruiting

Leukemia is the subject of 274 registered US clinical trials on ClinicalTrials.gov, 51 of them currently open to new participants. 19 are in Phase 3-4 (later-stage) and 193 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 37 of these trials.

The research picture

Leukemia has 274 registered US clinical trials, 51 of them open to new participants right now, about 19% of the total.

51
recruiting participants now
19%
of trials open to enrollment
19
in Phase 3–4 (later-stage)
37
top sponsor: M.D. Anderson Cancer Center
Phase 198Phase 295Phase 318Phase 41

Active & Recent Trials

274 total, page 5 of 6

COMPLETED Phase 2 20 participants

Combination Chemotherapy Plus Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloproliferative Disorders

Fred Hutchinson Cancer Center

NCT00002792

COMPLETED Phase 2 20 participants

Zevalin-Containing Nonmyeloablative Conditioning for Stem Cell Transplantation (SCT)

M.D. Anderson Cancer Center

NCT01490723

COMPLETED Phase 2 17 participants

Therapy of Chronic Lymphocytic Leukemia With Dasatinib (BMS-354825)

M.D. Anderson Cancer Center

NCT00364286

COMPLETED Phase 1 17 participants

Enasidenib in MDS &Non-proliferative Chronic Myelomonocytic Leukemia w/o IDH2 Mutation

Stanford University

NCT05282459

COMPLETED Phase 2 16 participants

Sorafenib Plus 5-Azacitidine Initial Therapy of Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MS) With FLT3-ITD Mutation

M.D. Anderson Cancer Center

NCT02196857

COMPLETED Phase 1 16 participants

Study to Assess Safety, Tolerability and Preliminary Efficacy of BKM120, PI3K Kinase Inhibitor, With Advanced Leukemias

M.D. Anderson Cancer Center

NCT01396499

COMPLETED 16 participants

Analysis of Blood and Bone Marrow to Detect Residual Disease in Patients With Previously Treated Hairy Cell Leukemia

Northwestern University

NCT00005619

COMPLETED Phase 2 16 participants

Allogeneic Transplantation From Related Haploidentical Donors

Stanford University

NCT00185692

COMPLETED Phase 1 16 participants

Cytarabine and UCN-01 in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia or Myelodysplastic Syndrome

M.D. Anderson Cancer Center

NCT00004263

COMPLETED Phase 1 16 participants

Arsenic Trioxide and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia

OHSU Knight Cancer Institute

NCT00053248

COMPLETED Phase 1 16 participants

Sirolimus in Combination With MEC in High Risk Myeloid Leukemias

Abramson Cancer Center at Penn Medicine

NCT00780104

COMPLETED Phase 1 15 participants

Alloreactive NK Cells for Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

M.D. Anderson Cancer Center

NCT00402558

COMPLETED 14 participants

Concurrent School Attendance And Cancer Therapy: The Experiences of 6-12 Year Old Pediatric Oncology Patients

St. Jude Children's Research Hospital

NCT01383473

COMPLETED Phase 1 14 participants

Decitabine and Peripheral Stem Cell Transplantation in Treating Patients Who Have Relapsed Following Bone Marrow Transplantation for Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia

M.D. Anderson Cancer Center

NCT00002832

COMPLETED Phase 1 13 participants

Arsenic Trioxide in Treating Patients With Refractory or Recurrent Acute Promyelocytic Leukemia

Washington University School of Medicine

NCT00008697

COMPLETED Phase 1 13 participants

Consolidation Therapy With Autologous T Cells Genetically Targeted to the B Cell Specific Antigen CD19 in Patients With Chronic Lymphocytic Leukemia Following Upfront Chemotherapy With Pentostatin, Cyclophosphamide and Rituximab

Memorial Sloan Kettering Cancer Center

NCT01416974

COMPLETED Phase 2 12 participants

Chemotherapy and a Donor Natural Killer Cell Infusion in Treating Patients With Relapsed or Persistent Leukemia or Myelodysplastic Syndrome After a Donor Stem Cell Transplant

Memorial Sloan Kettering Cancer Center

NCT00526292

COMPLETED Phase 2 11 participants

Chemotherapy in Treating Children With Relapsed Acute Leukemia, Acute Myeloid Leukemia, or Blastic Phase Chronic Myelogenous Leukemia

Children's Oncology Group

NCT00003735

COMPLETED Phase 1 11 participants

8-Chloro-Adenosine in Chronic Lymphocytic Leukemia

M.D. Anderson Cancer Center

NCT00714103

COMPLETED Phase 1 11 participants

Evaluating the Use of RFT5-dgA to Deplete Alloreactive Cells Prior to Haploidentical Stem Cell Transplantation

Baylor College of Medicine

NCT00586547

COMPLETED Phase 2 10 participants

Use of Topotecan in Patients With Refractory Acute Leukemia

US Department of Veterans Affairs

NCT00100477

COMPLETED Phase 1 9 participants

Panobinostat (LBH589) and Imatinib Mesylate in Treating Patients With Previously Treated Chronic Phase Chronic Myelogenous Leukemia

City of Hope Medical Center

NCT00686218

COMPLETED Phase 2 8 participants

Interferon Alfa in Treating Children With HIV-Related Cancer

Children's Oncology Group

NCT00002621

COMPLETED Phase 1 7 participants

Low-Dose Fludarabine, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer

University of California, San Francisco

NCT00301951

COMPLETED Phase 1 7 participants

Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

M.D. Anderson Cancer Center

NCT00005092

COMPLETED Phase 1 7 participants

A Safety and Tolerability Study of PCI-24781 in Subjects With Cancer

Pharmacyclics

NCT01149668

COMPLETED Phase 2 6 participants

Alloreactive Haploidentical Natural Killer (NK) Cells With Busulfan and Fludarabine/ATG

M.D. Anderson Cancer Center

NCT01390402

COMPLETED Phase 1 6 participants

Anti-Human CD45 Monoclonal Antibodies in Patients With Advanced Leukemia Prior to Allogeneic Stem Cell Transplantation

Baylor College of Medicine

NCT00057005

COMPLETED Phase 1 5 participants

Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer

University of California, San Francisco

NCT00304018

COMPLETED Phase 1 5 participants

Bone Marrow Transplantation With Specially Treated Bone Marrow in Treating Patients With Hematologic Cancer That Have Not Responded to Previous Therapy

Dana-Farber Cancer Institute

NCT00005988

COMPLETED Phase 2 3 participants

Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer

Roswell Park Cancer Institute

NCT00003661

COMPLETED Phase 1 3 participants

Vaccine Therapy and Imatinib Mesylate in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia

Dana-Farber Cancer Institute

NCT00301093

COMPLETED NA 2 participants

Compassionate Use of Campath-1H in Treating Patients With Refractory Prolymphocytic Leukemia or Chronic Lymphocytic Leukemia

Case Comprehensive Cancer Center

NCT00021151

COMPLETED Phase 1 1 participants

Vaccine Therapy in Treating Patients With Myelodysplastic Syndrome

Memorial Sloan Kettering Cancer Center

NCT00003959

COMPLETED Phase 2 1 participants

Photodynamic Therapy in Treating Patients With Lymphoma or Chronic Lymphocytic Leukemia

Roswell Park Cancer Institute

NCT00054171

COMPLETED Phase 3

Eculizumab in Treating Patients With Paroxysmal Nocturnal Hemoglobinuria

Jonsson Comprehensive Cancer Center

NCT00112983

COMPLETED Phase 2

Interferon Alfa and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia

Memorial Sloan Kettering Cancer Center

NCT00045422

COMPLETED Phase 2

Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Advanced Hematologic Cancer

Memorial Sloan Kettering Cancer Center

NCT00014469

COMPLETED Phase 1

Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia

Drexel University College of Medicine

NCT00003619

COMPLETED Phase 1

Ganciclovir Plus Arginine Butyrate in Treating Patients With Cancer or Lymphoproliferative Disorders Associated With the Epstein Barr Virus

Boston Medical Center

NCT00006340

COMPLETED NA

Vaccine Therapy in Preventing Flu in Children With Acute Lymphoblastic Leukemia

Roswell Park Cancer Institute

NCT00022035

COMPLETED Phase 2

Chemotherapy Followed by Peripheral Stem Cell Transplantation And Biological Therapy in Treating Patients With Chronic Myelogenous Leukemia

Fred Hutchinson Cancer Center

NCT00005948

COMPLETED Phase 2

Bryostatin 1 and Cytarabine in Treating Patients With Relapsed Acute Myelogenous Leukemia

Virginia Commonwealth University

NCT00017342

COMPLETED Phase 2

Busulfan and Cyclophosphamide Followed by Bone Marrow Transplantation in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

Northwestern University

NCT00004896

COMPLETED Phase 1

17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia That Did Not Respond to Imatinib Mesylate

Jonsson Comprehensive Cancer Center

NCT00100997

COMPLETED Phase 2

Combination Chemotherapy and Bone Marrow Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome

Memorial Sloan Kettering Cancer Center

NCT00002502

COMPLETED Phase 2

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Acute Leukemia

Herbert Irving Comprehensive Cancer Center

NCT00008190

COMPLETED Phase 1

R115777 in Treating Patients With Refractory or Recurrent Acute Leukemia or Chronic Myelogenous Leukemia

University of Maryland, Baltimore

NCT00004009

COMPLETED Phase 1

Perifosine in Treating Patients With Refractory Solid Tumors or Hematologic Cancer

National Cancer Institute (NCI)

NCT00019656

COMPLETED Phase 1

UCN-01 in Treating Patients With Advanced Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT00003289

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Phase Distribution

PhaseTrial count
Phase 1 98
Phase 2 95
Phase 3 18
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Leukemia Trial Landscape

274 indexed Leukemia studies · 51 recruiting (19%).

Phase mix: 19 late (III/IV) vs 193 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (37 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Leukemia?

PlainTrial tracks 274 US clinical trials for Leukemia, of which 51 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.