Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 51 recruiting now official registry

Leukemia clinical trials

51 of 274 indexed Leukemia trials are currently recruiting.

274 US clinical trials · 51 currently recruiting

Leukemia is the subject of 274 registered US clinical trials on ClinicalTrials.gov, 51 of them currently open to new participants. 19 are in Phase 3-4 (later-stage) and 193 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 37 of these trials.

The research picture

Leukemia has 274 registered US clinical trials, 51 of them open to new participants right now, about 19% of the total.

51
recruiting participants now
19%
of trials open to enrollment
19
in Phase 3–4 (later-stage)
37
top sponsor: M.D. Anderson Cancer Center
Phase 198Phase 295Phase 318Phase 41

Active & Recent Trials

274 total, page 4 of 6

COMPLETED Phase 1 49 participants

INCB18424 in Treating Young Patients With Relapsed or Refractory Solid Tumor, Leukemia, or Myeloproliferative Disease

Children's Oncology Group

NCT01164163

COMPLETED Phase 2 49 participants

Bone Marrow Transplantation in Treating Patients With Chronic Lymphocytic Leukemia

M.D. Anderson Cancer Center

NCT00002844

COMPLETED 48 participants

Natural History Study of Patients With Chronic Myelogenous Leukemia

Dana-Farber Cancer Institute

NCT00429910

COMPLETED Phase 2 48 participants

Allo Non-myeloablative SCT Utilizing Matched Family Member Stem Cells Purged Using Campath

David Rizzieri, MD

NCT00578942

COMPLETED 48 participants

Registry Study of T Cell Depleted Allo Non-Myeloablative Stem Cell Transplant

Duke University

NCT01904175

COMPLETED NA 45 participants

Evaluating the Feasibility of a Digital Health Coaching Program for Individuals Following CAR T Therapy

Pack Health

NCT05064787

COMPLETED Phase 4 45 participants

Bone Marrow Transplantation in Treating Patients With Hematologic Cancer

University of Maryland, Baltimore

NCT00003398

COMPLETED Phase 2 45 participants

Lenalidomide With or Without Rituximab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia

Roswell Park Cancer Institute

NCT00096044

COMPLETED Phase 2 45 participants

Lenalidomide (Revlimid) in Chronic Lymphocytic Leukemia (CLL)

M.D. Anderson Cancer Center

NCT00267059

COMPLETED 43 participants

Neurocognitive and Psychosocial Outcomes in Survivors of Childhood Leukemia With Down Syndrome

St. Jude Children's Research Hospital

NCT02859389

COMPLETED Phase 1 42 participants

BMS-354825 in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia That Is Resistant to Imatinib Mesylate

Jonsson Comprehensive Cancer Center

NCT00064233

COMPLETED Phase 1 41 participants

T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer

Masonic Cancer Center, University of Minnesota

NCT00602693

COMPLETED Phase 1 40 participants

Busulfan, Antithymocyte Globulin, and Fludarabine Followed By a Donor Stem Cell Transplant in Treating Young Patients With Blood Disorders, Bone Marrow Disorders, Chronic Myelogenous Leukemia in First Chronic Phase, or Acute Myeloid Leukemia in First Remission

University of California, San Francisco

NCT00305708

COMPLETED Phase 1 40 participants

Total Body Irradiation With Fludarabine Followed by Combined Umbilical Cord Blood (UCB) Transplants

Duke University

NCT00606437

COMPLETED Phase 1 40 participants

Stem Cell Transplant for Patients With Blood Malignancy Using Donors and Less Toxic Chemotherapy With CAMPATH 1H

Baylor College of Medicine

NCT00048412

COMPLETED Phase 2 40 participants

Thiotepa Plus Fludarabine+ Melphalan as the Preparative Regime for Alternative Donor Transplantation

Case Comprehensive Cancer Center

NCT03342196

COMPLETED Phase 2 39 participants

A Phase II Open-Label Study of High-Dose Cytarabine and Clofarabine in Adult Patients With Refractory or Relapsed Acute Myelogenous Leukemia or Refractory or Relapsed Acute Lymphoblastic Leukemia

Wake Forest University Health Sciences

NCT01656031

COMPLETED NA 39 participants

Donor Lymphocyte Infusion in Treating Patients With Recurrent or Persistent Hematologic Cancer After Donor Stem Cell Transplant

Roswell Park Cancer Institute

NCT00534118

COMPLETED Phase 2 38 participants

CLAG Gleevec in Relapsed or Refractory Acute Myeloid Leukemia (AML)

H. Lee Moffitt Cancer Center and Research Institute

NCT00955916

COMPLETED Phase 1 38 participants

Clofarabine, Melphalan, and Thiotepa Followed By a Donor Stem Cell Transplant in Treating Patients With High-Risk and/or Advanced Hematologic Cancer or Other Disease

Memorial Sloan Kettering Cancer Center

NCT00423514

COMPLETED NA 37 participants

Exercise Program for Adolescents and Young Adults With Cancer

M.D. Anderson Cancer Center

NCT00502749

COMPLETED Phase 2 36 participants

BL22 Immunotoxin in Treating Patients Previously Treated With Cladribine for Hairy Cell Leukemia

MedImmune

NCT00074048

COMPLETED Phase 2 36 participants

Omacetaxine and Low Dose Cytarabine in Older Patients With Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS)

M.D. Anderson Cancer Center

NCT01272245

COMPLETED Phase 1 36 participants

Phase I/II Study of 5-Azacytidine With Ara-C in Patients With Relapsed/Refractory Acute Myelogenous Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)

M.D. Anderson Cancer Center

NCT00569010

COMPLETED Phase 2 35 participants

Ixabepilone in Treating Patients With Relapsed or Refractory Lymphoproliferative Disorders

Memorial Sloan Kettering Cancer Center

NCT00052572

COMPLETED Phase 2 35 participants

506U78 in Treating Patients With Refractory or Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

National Cancer Institute (NCI)

NCT00003545

COMPLETED Phase 1 35 participants

VNP40101M in Treating Patients With Richter Syndrome or Refractory or Relapsed Chronic Lymphocytic Leukemia or Other Lymphoproliferative Disorders

Vion Pharmaceuticals

NCT00304005

COMPLETED Phase 2 34 participants

Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

Case Comprehensive Cancer Center

NCT00054327

COMPLETED Phase 2 34 participants

Campath-1H + FK506 and Methylprednisolone for GVHD

Case Comprehensive Cancer Center

NCT00109993

COMPLETED Phase 2 33 participants

Rituximab, Alemtuzumab, and GM-CSF As First-Line Therapy in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia

Mayo Clinic

NCT00562328

COMPLETED NA 33 participants

Erwinase Study in Patients With Acute Lymphoblastic Leukemia

M.D. Anderson Cancer Center

NCT00506597

COMPLETED Phase 2 32 participants

Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer

City of Hope Medical Center

NCT00589563

COMPLETED Phase 1 30 participants

Pilot Study to Determine Effects of the Btk Inhibitor PCI-32765 on Leukemia Cell Kinetics and Trafficking, Using Heavy Water Labeling in Subjects With CLL and SLL

M.D. Anderson Cancer Center

NCT01752426

COMPLETED Phase 2 30 participants

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Relapsed Acute Lymphocytic Leukemia

University of Nebraska

NCT00002638

COMPLETED Phase 2 30 participants

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia

Fred Hutchinson Cancer Center

NCT00002674

COMPLETED Phase 1 29 participants

Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of Nelarabine in Patients With Relapsed/Refractory Lymphoid Malignancies

M.D. Anderson Cancer Center

NCT01094860

COMPLETED Phase 1 29 participants

Fenretinide in Treating Patients With Refractory or Relapsed Hematologic Cancer

California Cancer Consortium

NCT00104923

COMPLETED Phase 1 28 participants

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Pediatric Brain Tumor Consortium

NCT00006246

COMPLETED Phase 1 24 participants

Chemotherapy Given With Amifostine and Filgrastim in Treating Patients With Recurrent or Metastatic Cancer

Roswell Park Cancer Institute

NCT00003294

COMPLETED Phase 2 24 participants

Maintenance Azacitidine in Elderly Patients With Acute Myeloid Leukemia (AML) in CR After Induction Chemotherapy

H. Lee Moffitt Cancer Center and Research Institute

NCT00387647

COMPLETED Phase 1 23 participants

Azacytidine and Bortezomib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes

Ohio State University Comprehensive Cancer Center

NCT00624936

COMPLETED Phase 2 23 participants

Phase II Eltrombopag in Chronic Lymphocytic Leukemia (CLL)

M.D. Anderson Cancer Center

NCT01168921

COMPLETED Phase 1 23 participants

ABT-888 in Patients With Refractory Solid Tumors or Hematologic Cancer

National Institutes of Health Clinical Center (CC)

NCT00387608

COMPLETED Phase 1 22 participants

Immunotherapy Using Lenalidomide + Bystander Vaccine in High Risk Myelodysplastic Syndrome (MDS)

H. Lee Moffitt Cancer Center and Research Institute

NCT00840931

COMPLETED Phase 1 22 participants

Dose Escalation Trial of WT1-Sensitized T Cells for Residual or Relapsed Leukemia After Allogeneic Hematopoietic Progenitor Cell Transplantation

Memorial Sloan Kettering Cancer Center

NCT00620633

COMPLETED Phase 2 21 participants

Donor Peripheral Stem Cell Transplant in Treating Patients With Relapsed Acute Myeloid Leukemia

Masonic Cancer Center, University of Minnesota

NCT00274846

COMPLETED Phase 1 21 participants

A Study of Selinexor in Combination With Daunorubicin and Cytarabine for Untreated AML

H. Lee Moffitt Cancer Center and Research Institute

NCT02403310

COMPLETED 20 participants

Circulating microRNAs as Disease Markers in Pediatric Cancers

Ann & Robert H Lurie Children's Hospital of Chicago

NCT01541800

COMPLETED Phase 1 20 participants

Triciribine Phosphate Monohydrate (TCN-PM, VD-0002) in Adult Patients With Advanced Hematologic Malignancies

Prescient Therapeutics

NCT00642031

COMPLETED Phase 2 20 participants

CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant

New York Medical College

NCT01049854

← Previous Page 4 of 6 Next →

Phase Distribution

PhaseTrial count
Phase 1 98
Phase 2 95
Phase 3 18
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Leukemia Trial Landscape

274 indexed Leukemia studies · 51 recruiting (19%).

Phase mix: 19 late (III/IV) vs 193 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (37 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Leukemia?

PlainTrial tracks 274 US clinical trials for Leukemia, of which 51 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.