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COMPLETED Phase 2

Allogeneic Transplantation From Related Haploidentical Donors

NCT00185692 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of the study is to evaluate the feasibility and safety of transplanting CD34+ selected hematopoietic cells from a haploidentical related donor following a nonmyeloablative regimen of total lymphoid irradiation (TLI) and antithymocyte globulin (ATG).

Interventions

  • DRUG G-CSF
  • DRUG Mycophenolate Mofetil
  • DRUG Cyclosporine
  • PROCEDURE non-myeloablative hematopoietic cell transplantation
  • DRUG Anti-Thymocyte Globulin

Study Locations (1)

California

  • Stanford University School of Medicine — Stanford

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2000-08
Est. Completion 2010-12
Phase Phase 2

Sponsor

Stanford University

1,643 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00185692

The ClinicalTrials.gov registry entry for NCT00185692 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Stanford University, which has 1,643 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 8 conditions, with Leukemia appearing as the primary indexed condition, and to 5 interventions — of which G-CSF is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00185692 reports 1 study location spanning 1 distinct geographic area — top geographies include California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00185692 about?

NCT00185692 is a clinical study titled "Allogeneic Transplantation From Related Haploidentical Donors". The purpose of the study is to evaluate the feasibility and safety of transplanting CD34+ selected hematopoietic cells from a haploidentical related donor following a nonmyeloablative regimen of total lymphoid irradiation (TLI) and antithymocyte globulin (ATG).

What is the current status of trial NCT00185692?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 16 participants. The study started on 2000-08. Estimated completion is 2010-12.

What conditions does trial NCT00185692 study?

This clinical trial studies the following conditions: Leukemia, Graft Versus Host Disease, MDS, Hodgkin's Disease, Blood Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00185692?

The interventions under investigation include: G-CSF (DRUG), Mycophenolate Mofetil (DRUG), Cyclosporine (DRUG), non-myeloablative hematopoietic cell transplantation (PROCEDURE), Anti-Thymocyte Globulin (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00185692?

This trial is sponsored by Stanford University, which has 1,643 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00185692 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial