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NCT00005092 · ClinicalTrials.gov registry record · Phase 1

Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

A Phase 1 study of Lymphoma and Leukemia, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 1
Development phase
7
Enrollment target
3
Study locations

NCT00005092 is a Phase 1 study of Lymphoma and Leukemia that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 7 participants, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (99% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT00005092, a Phase 1 study of Lymphoma and Leukemia, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
7 participants
Enrollment target
3
Study locations

Study Summary

RATIONALE: Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by the chemotherapy or radiation therapy used to kill tumor cells. Sometimes the transplanted cells are rejected by the body's normal tissues. Transplanting donated cells that have been treated with psoralen may prevent this from happening. PURPOSE: Phase I trial to study the effectiveness of chemotherapy, radiation therapy, and psoralen-treated donor cells in treating patients who are undergoing peripheral stem cell transplantation for hematologic cancer.

Interventions

  • DRUG Cyclophosphamide
  • DRUG Thiotepa
  • DRUG Psoralen
  • PROCEDURE Allogeneic bone marrow transplantation
  • PROCEDURE In vitro-treated peripheral blood stem cell transplantation (PBSCT)

Study Locations (3)

Illinois

  • University of Illinois at Chicago - Chicago

Missouri

  • Washington University Barnard Cancer Center - St Louis

Texas

  • University of Texas - MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 1999-05-28
Est. Completion 2002-08-28
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT00005092

The ClinicalTrials.gov registry entry for NCT00005092 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (99% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Lymphoma appearing as the primary indexed condition, and to 5 interventions - of which Cyclophosphamide is the first listed.

NCT00005092 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Illinois, Missouri, Texas.

Frequently Asked Questions

What is clinical trial NCT00005092 about?

NCT00005092 is a clinical study titled "Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer". RATIONALE: Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by the chemotherapy or radiation therapy used to kill tumor cells. Sometimes the transplanted cells are rejected by the body's normal tissues. Transplanting donated cells that have been treated wi...

What is the current status of trial NCT00005092?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 7 participants. The study started on 1999-05-28. Estimated completion is 2002-08-28.

What conditions does trial NCT00005092 study?

This clinical trial studies the following conditions: Lymphoma, Leukemia, Myelodysplastic Syndromes, Multiple Myeloma and Plasma Cell Neoplasm.

What interventions are being tested in trial NCT00005092?

The interventions under investigation include: Cyclophosphamide (DRUG), Thiotepa (DRUG), Psoralen (DRUG), Allogeneic bone marrow transplantation (PROCEDURE), In vitro-treated peripheral blood stem cell transplantation (PBSCT) (PROCEDURE).

Who is sponsoring clinical trial NCT00005092?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00005092 being conducted?

This trial has 3 study locations across Illinois, Missouri, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.