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NCT00003619 · ClinicalTrials.gov registry record · Phase 1
Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia
A Phase 1 study of Leukemia and Myelodysplastic Syndromes, sponsored by Drexel University College of Medicine.
- Completed
- Registry status
- Phase 1
- Development phase
- 2
- Study locations
NCT00003619: Completed Phase 1 study of Leukemia and Myelodysplastic Syndromes, sponsored by Drexel University College of Medicine.
NCT00003619 is a Phase 1 study of Leukemia and Myelodysplastic Syndromes that has completed, run by Drexel University College of Medicine. The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00003619, a Phase 1 study of Leukemia and Myelodysplastic Syndromes, has completed, sponsored by Drexel University College of Medicine.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 2
- Study locations
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. Isotretinoin may help cancer cells develop into normal white blood cells. PURPOSE: Phase I/II trial of topotecan, fludarabine, cytarabine, and filgrastim followed by peripheral stem cell transplantation or isotretinoin in treating patients who have acute myeloid leukemia, myelodysplastic syndrome, or recurrent or refractory acute lymphocytic leukemia.
Conditions Studied
Interventions
- DRUG etoposide
- BIOLOGICAL filgrastim
- DRUG cytarabine
- DRUG busulfan
- DIETARY_SUPPLEMENT vitamin E
Study Locations (2)
Pennsylvania
- Medical College of Pennsylvania Hospital - Philadelphia
- Medical College of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Start Date | 1998-02 |
| Est. Completion | 2004-04 |
| Phase | Phase 1 |
What the finished NCT00003619 record still lists
NCT00003619 is an interventional study that assigns participants to a tested intervention. An enrollment target was not published in the registry record, which is common for early-stage or observational entries.
The record links to 4 conditions, with Leukemia appearing as the primary indexed condition, and to 5 interventions - of which etoposide is the first listed.
NCT00003619 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00003619 about?
NCT00003619 is a clinical study titled "Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia". RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. Isotretinoin may help cancer cells develop into no...
What is the current status of trial NCT00003619?
This trial is currently completed. It is a Phase 1 study. The study started on 1998-02. Estimated completion is 2004-04.
What conditions does trial NCT00003619 study?
This clinical trial studies the following conditions: Leukemia, Myelodysplastic Syndromes, Thrombocytopenia, Chronic Myeloproliferative Disorders.
What interventions are being tested in trial NCT00003619?
The interventions under investigation include: etoposide (DRUG), filgrastim (BIOLOGICAL), cytarabine (DRUG), busulfan (DRUG), vitamin E (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT00003619?
This trial is sponsored by Drexel University College of Medicine, which has 25 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00003619 being conducted?
This trial has 2 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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