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NCT00780104 · ClinicalTrials.gov registry record · Phase 1

Sirolimus in Combination With MEC in High Risk Myeloid Leukemias

A Phase 1 study of Leukemia and AML, sponsored by Abramson Cancer Center at Penn Medicine.

Completed
Registry status
Phase 1
Development phase
16
Enrollment target
1
Study location

NCT00780104: Completed Phase 1 study of Leukemia and AML, sponsored by Abramson Cancer Center at Penn Medicine.

NCT00780104 is a Phase 1 study of Leukemia and AML that has completed, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 16 participants, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00780104, a Phase 1 study of Leukemia and AML, has completed, sponsored by Abramson Cancer Center at Penn Medicine.

COMPLETED
Registry status
Phase 1
Development phase
16 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to evaluate the side effects of sirolimus (rapamycin) given in combination with chemotherapy (Mitoxantrone + Etoposide + Cytarabine (MEC)) on high risk myeloid leukemias.

Interventions

  • DRUG Rapamycin, Mitoxantrone, Etoposide, Cytarabine
  • DRUG Rapamycin + MEC

Study Locations (1)

Pennsylvania

  • University of Pennsylvania Abramson Cancer Center - Philadelphia

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2007-07
Est. Completion 2010-06
Phase Phase 1

What the finished NCT00780104 record still lists

NCT00780104 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (97% lower).

The record links to 4 conditions, with Leukemia appearing as the primary indexed condition, and to 2 interventions - of which Rapamycin, Mitoxantrone, Etoposide, Cytarabine is the first listed.

NCT00780104 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT00780104 about?

NCT00780104 is a clinical study titled "Sirolimus in Combination With MEC in High Risk Myeloid Leukemias". The purpose of this study is to evaluate the side effects of sirolimus (rapamycin) given in combination with chemotherapy (Mitoxantrone + Etoposide + Cytarabine (MEC)) on high risk myeloid leukemias.

What is the current status of trial NCT00780104?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2007-07. Estimated completion is 2010-06.

What conditions does trial NCT00780104 study?

This clinical trial studies the following conditions: Leukemia, AML, CML, Myeloid Leukemias.

What interventions are being tested in trial NCT00780104?

The interventions under investigation include: Rapamycin, Mitoxantrone, Etoposide, Cytarabine (DRUG), Rapamycin + MEC (DRUG).

Who is sponsoring clinical trial NCT00780104?

This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00780104 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Leukemia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00780104's enrollment target sits among peer trials

16 195th of 233 higher than 31 of 233 other Leukemia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00780104, the US trial registry maintained by the National Library of Medicine. NCT00780104 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.