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ClinicalTrials.gov 101 recruiting now early-phase tilt #33 of 28,707 conditions

Pancreatic Cancer: early-phase trial registry

101 of 283 indexed Pancreatic Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #33 of 28,707 conditions by registered trial count.

283 US clinical trials · 101 currently recruiting · #33 of 28,707 conditions by registered trial count

Pancreatic Cancer: 283 US clinical trials tracked, 101 recruiting.

Pancreatic Cancer is the subject of 283 registered US clinical trials on ClinicalTrials.gov, 101 of them currently open to new participants. 12 are in Phase 3-4 (later-stage) and 180 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 19 of these trials.

Enrollment posture brief

Registry condition pancreatic-cancer

OPEN 101 | RECR 36% | LATE 12 | EARLY 180 | RANK #33 | SPON 19

Nearest open-share peer: Acute Respiratory Failure (36% recruiting · 14 trials)

Major Depressive Disorder38.5%Pancreatic Cancer (this)36%Melanoma33.1%Healthy Volunteers27.8%Leukemia18.6%
Open-enrollment share among volume-matched conditions near Pancreatic Cancer

Pancreatic Cancer lists 101 open slots (36% of 283 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Pancreatic Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Pancreatic Cancer recruits in line with its size-band peers.

    101 of 283 indexed trials (35.7%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Pancreatic Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 19 of 283 trials (6.7%). 165 distinct sponsors appear on at least one study for this condition label.

  3. Most Pancreatic Cancer trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 279 trials that report a genuine target (sentinel values excluded). 170 of those (60.9%) plan for fewer than 100 participants.

  4. Pancreatic Cancer research is mostly interventional.

    237 interventional and 46 observational studies make up this index (83.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1114Phase 266Phase 310Phase 42

Open and recent trials

283 total, page 1 of 6

RECRUITING open-ended (no fixed target)

Integrated Cancer Repository for Cancer Research

University of Nebraska

NCT02012699

RECRUITING 20,000 participants

Collecting Medical Information and Tissue Samples From Patients With Pancreatic Cancer or Other Pancreatic Disorders

Mayo Clinic

NCT00830557

RECRUITING 10,000 participants

Pancreatic Adenocarcinoma Gene Environment Risk Study

University of Pittsburgh

NCT00912717

RECRUITING 9,600 participants

Sample Collection for Ongoing Research and Product Evaluation Study

Natera

NCT07318051

RECRUITING Early Phase 1 5,000 participants

Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals

Dana-Farber Cancer Institute

NCT06122896

RECRUITING 5,000 participants

A Prospective Registry for Patients at High-Risk for Pancreatic Cancer

Mayo Clinic

NCT06151223

RECRUITING 5,000 participants

Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients

Vanderbilt University Medical Center

NCT00899626

RECRUITING 4,000 participants

UCSF PANC Cyst Registry

University of California, San Francisco

NCT04291651

RECRUITING 2,000 participants

Pancreatic Cancer Detection Consortium

City of Hope Medical Center

NCT06388967

RECRUITING 1,400 participants

EXoPERT EMERALD Clinical Study

EXoPERT

NCT07186296

RECRUITING 1,174 participants

Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas

H. Lee Moffitt Cancer Center and Research Institute

NCT04275557

RECRUITING NA 1,020 participants

Video Education With Result Dependent dIsclosure

Dana-Farber Cancer Institute

NCT05225428

RECRUITING 1,000 participants

PANCREATIC DISEASE COHORT A Registry and Biospecimen Bank to Better Understand Pancreatic Disease

Columbia University

NCT01102556

RECRUITING 800 participants

A Pancreatic Cancer Screening Study in Individuals With New-Onset or Deteriorating Diabetes Mellitus

Nuvance Health

NCT03937453

RECRUITING 775 participants

Evaluation of a Mixed Meal Test for Diagnosis and Characterization and Type 3c Diabetes Mellitus Secondary to Pancreatic Cancer and Chronic Pancreatitis (DETECT)

M.D. Anderson Cancer Center

NCT03460769

RECRUITING 700 participants

A Study of Blood Based Biomarkers for Pancreas Adenocarcinoma

Memorial Sloan Kettering Cancer Center

NCT03334708

RECRUITING 620 participants

Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

University of Missouri-Columbia

NCT02838836

RECRUITING Phase 3 614 participants

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

Astellas Pharma Global Development

NCT07409272

RECRUITING Phase 1 574 participants

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

Revolution Medicines

NCT07349537

RECRUITING Phase 1 512 participants

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer (NSCLC), Head and Neck Squamous Cell Carcinoma (HNSCC) and Other Solid Tumors, Receiving Intravenous (IV) Infusion of Azirkitug (ABBV-514) Alone or in Combination With Budigalimab or Bevacizumab

AbbVie

NCT05005403

RECRUITING Phase 3 500 participants

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

Revolution Medicines

NCT07252232

RECRUITING 500 participants

American Hepato-Pancreato-Biliary Association (AHPBA) Pancreatic Irreversible Electroporation (IRE) Registry

University of Louisville

NCT02674100

RECRUITING Phase 1 490 participants

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

Eli Lilly and Company

NCT06238479

RECRUITING NA 445 participants

Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients

Memorial Sloan Kettering Cancer Center

NCT04751435

RECRUITING Phase 1 420 participants

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

Eli Lilly and Company

NCT06465069

RECRUITING Phase 1 405 participants

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

ArriVent BioPharma

NCT07066657

RECRUITING Phase 1 403 participants

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

Frontier Medicines Corporation

NCT06244771

RECRUITING 320 participants

Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

University of Missouri-Columbia

NCT03551951

RECRUITING 310 participants

Artificial Intelligence in Endoscopic Ultrasound

Orlando Health

NCT06564571

RECRUITING NA 259 participants

Computed Tomography in Diagnosing Patients With Pancreatic or Hepatobiliary Cancer

M.D. Anderson Cancer Center

NCT02361320

RECRUITING NA 257 participants

Resilience and Equity in Aging, Cancer, and Health (REACH)

Dana-Farber Cancer Institute

NCT04674267

RECRUITING Phase 1 250 participants

Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)

EMD Serono Research & Development Institute

NCT06710132

RECRUITING Phase 1 242 participants

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

VM Oncology

NCT03556228

RECRUITING Phase 2 240 participants

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Udai Kammula

NCT03935893

RECRUITING Phase 1 220 participants

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

Bold Therapeutics

NCT04421820

RECRUITING 200 participants

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

A2 Biotherapeutics

NCT04981119

RECRUITING 200 participants

Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

Abramson Cancer Center at Penn Medicine

NCT02478892

RECRUITING Phase 1 195 participants

A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors

PAQ Therapeutics

NCT07300150

RECRUITING 181 participants

Interrogation of Exosome-mediated Intercellular Signaling in Patients With Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT02393703

RECRUITING NA 178 participants

GENOCARE: A Prospective, Randomized Clinical Trial of Genotype-Guided Dosing Versus Usual Care

Reema A. Patel

NCT05391126

RECRUITING Phase 1 165 participants

A Study of PHN-012 in Patients With Advanced Solid Tumors

Pheon Therapeutics

NCT07127874

RECRUITING Phase 1 150 participants

A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors

Qurgen

NCT05989724

RECRUITING NA 140 participants

EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope

Orlando Health

NCT06340620

RECRUITING Phase 1 134 participants

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

RasCal Therapeutics

NCT04678648

RECRUITING NA 134 participants

Stereotactic Adaptive Radiation Therapy of Borderline Resectable Pancreatic Cancer an Individualized Approach

Varian, a Siemens Healthineers Company

NCT05764720

RECRUITING Phase 2 125 participants

Pancreatic Cancer Adaptive Neoadjuvant Chemotherapy Trial

Medical College of Wisconsin

NCT03322995

RECRUITING 125 participants

Evaluating Obesity-Mediated Mechanisms of Pancreatic Carcinogenesis in Minority Populations

H. Lee Moffitt Cancer Center and Research Institute

NCT05687188

RECRUITING Phase 1 124 participants

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

National Cancer Institute (NCI)

NCT02830724

RECRUITING Phase 1 122 participants

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

AtlasMedx, Incorporated

NCT04503265

RECRUITING 120 participants

A First-in-Human Study of FID-022 in Solid Tumor Patients

H. Lee Moffitt Cancer Center and Research Institute

NCT07249775

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Phase Distribution

PhaseTrial count
Phase 1 114
Phase 2 66
Phase 3 10
Phase 4 2

Named interventions

Most-linked intervention names on Pancreatic Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Gemcitabine Drug
20 trials
Cyclophosphamide Drug
10 trials
gemcitabine hydrochloride Drug
7 trials
Nivolumab Drug
6 trials
Pembrolizumab Drug
6 trials
erlotinib hydrochloride Drug
5 trials
Irinotecan Drug
5 trials
Oxaliplatin Drug
5 trials

US sites by state

Facility locations filed on Pancreatic Cancer trials. A trial with sites in several states counts in each.

New York 74 trials
California 72 trials
Florida 67 trials
Texas 62 trials
Massachusetts 43 trials
Maryland 38 trials
Michigan 35 trials
Arizona 32 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Pancreatic Cancer page

283 registered trials, 101 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pancreatic Cancer condition card totals 283 registered trials; most-linked intervention Gemcitabine; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.