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NCT00004263 · ClinicalTrials.gov registry record · Phase 1
Cytarabine and UCN-01 in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia or Myelodysplastic Syndrome
A Phase 1 study of Leukemia and Myelodysplastic Syndromes, sponsored by M.D. Anderson Cancer Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
- 2
- Study locations
NCT00004263: Completed Phase 1 study of Leukemia and Myelodysplastic Syndromes, sponsored by M.D. Anderson Cancer Center.
NCT00004263 is a Phase 1 study of Leukemia and Myelodysplastic Syndromes that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 16 participants, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00004263, a Phase 1 study of Leukemia and Myelodysplastic Syndromes, has completed, sponsored by M.D. Anderson Cancer Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
- 2
- Study locations
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. UCN-01 may make cancer cells more sensitive to cytarabine. PURPOSE: Phase I trial to study the effectiveness of cytarabine and UCN-01 in treating patients who have refractory or relapsed acute myelogenous leukemia or myelodysplastic syndrome.
Conditions Studied
Interventions
- DRUG Cytarabine (Ara-C)
- DRUG 7-hydroxystaurosporine (UCN-01)
Study Locations (2)
Ohio
- Arthur G. James Cancer Hospital - Ohio State University - Columbus
Texas
- University of Texas - MD Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 1999-12 |
| Est. Completion | 2007-01 |
| Phase | Phase 1 |
What the finished NCT00004263 record still lists
NCT00004263 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Leukemia appearing as the primary indexed condition, and to 2 interventions - of which Cytarabine (Ara-C) is the first listed.
NCT00004263 reports a single indexed study location in Ohio, Texas.
Frequently Asked Questions
What is clinical trial NCT00004263 about?
NCT00004263 is a clinical study titled "Cytarabine and UCN-01 in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia or Myelodysplastic Syndrome". RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. UCN-01 may make cancer cells more sensitive to cytarabine. PURPOSE: Phase I trial to study the effectiveness of cytarabine and UCN-01 in treating patients who have refractory or ...
What is the current status of trial NCT00004263?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 1999-12. Estimated completion is 2007-01.
What conditions does trial NCT00004263 study?
This clinical trial studies the following conditions: Leukemia, Myelodysplastic Syndromes.
What interventions are being tested in trial NCT00004263?
The interventions under investigation include: Cytarabine (Ara-C) (DRUG), 7-hydroxystaurosporine (UCN-01) (DRUG).
Who is sponsoring clinical trial NCT00004263?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00004263 being conducted?
This trial has 2 study locations across Ohio, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00004263's enrollment target sits among peer trials
16 195th of 233 higher than 31 of 233 other Leukemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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