Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00004263 · ClinicalTrials.gov registry record · Phase 1

Cytarabine and UCN-01 in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia or Myelodysplastic Syndrome

A Phase 1 study of Leukemia and Myelodysplastic Syndromes, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 1
Development phase
16
Enrollment target
2
Study locations

NCT00004263 is a Phase 1 study of Leukemia and Myelodysplastic Syndromes that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 16 participants, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 2 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00004263, a Phase 1 study of Leukemia and Myelodysplastic Syndromes, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
16 participants
Enrollment target
2
Study locations

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. UCN-01 may make cancer cells more sensitive to cytarabine. PURPOSE: Phase I trial to study the effectiveness of cytarabine and UCN-01 in treating patients who have refractory or relapsed acute myelogenous leukemia or myelodysplastic syndrome.

Interventions

  • DRUG Cytarabine (Ara-C)
  • DRUG 7-hydroxystaurosporine (UCN-01)

Study Locations (2)

Ohio

  • Arthur G. James Cancer Hospital - Ohio State University - Columbus

Texas

  • University of Texas - MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 1999-12
Est. Completion 2007-01
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT00004263

The ClinicalTrials.gov registry entry for NCT00004263 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (97% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Leukemia appearing as the primary indexed condition, and to 2 interventions - of which Cytarabine (Ara-C) is the first listed.

NCT00004263 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Ohio, Texas.

Frequently Asked Questions

What is clinical trial NCT00004263 about?

NCT00004263 is a clinical study titled "Cytarabine and UCN-01 in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia or Myelodysplastic Syndrome". RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. UCN-01 may make cancer cells more sensitive to cytarabine. PURPOSE: Phase I trial to study the effectiveness of cytarabine and UCN-01 in treating patients who have refractory or ...

What is the current status of trial NCT00004263?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 1999-12. Estimated completion is 2007-01.

What conditions does trial NCT00004263 study?

This clinical trial studies the following conditions: Leukemia, Myelodysplastic Syndromes.

What interventions are being tested in trial NCT00004263?

The interventions under investigation include: Cytarabine (Ara-C) (DRUG), 7-hydroxystaurosporine (UCN-01) (DRUG).

Who is sponsoring clinical trial NCT00004263?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00004263 being conducted?

This trial has 2 study locations across Ohio, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Leukemia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.