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NCT00003959 · ClinicalTrials.gov registry record · Phase 1

Vaccine Therapy in Treating Patients With Myelodysplastic Syndrome

A Phase 1 study of Leukemia and Myelodysplastic Syndromes, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
Phase 1
Development phase
1
Enrollment target
1
Study location

NCT00003959: Completed Phase 1 study of Leukemia and Myelodysplastic Syndromes, sponsored by Memorial Sloan Kettering Cancer Center.

NCT00003959 is a Phase 1 study of Leukemia and Myelodysplastic Syndromes that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 1 participants, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00003959, a Phase 1 study of Leukemia and Myelodysplastic Syndromes, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
1 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: A vaccine made from a person's myelodysplasia cells may make the body build an immune response to kill cancer cells. Combining vaccine therapy with sargramostim may kill more cancer cells. PURPOSE: Phase I trial to study the effectiveness of vaccine therapy plus sargramostim in treating patients who have myelodysplastic syndrome.

Interventions

  • BIOLOGICAL sargramostim
  • BIOLOGICAL ras peptide cancer vaccine

Study Locations (1)

New York

  • Memorial Sloan-Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 1999-06
Phase Phase 1
Memorial Sloan Kettering Cancer Center

1,884 total trials

What the finished NCT00003959 record still lists

NCT00003959 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (100% lower).

The record links to 2 conditions, with Leukemia appearing as the primary indexed condition, and to 2 interventions - of which sargramostim is the first listed.

NCT00003959 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT00003959 about?

NCT00003959 is a clinical study titled "Vaccine Therapy in Treating Patients With Myelodysplastic Syndrome". RATIONALE: A vaccine made from a person's myelodysplasia cells may make the body build an immune response to kill cancer cells. Combining vaccine therapy with sargramostim may kill more cancer cells. PURPOSE: Phase I trial to study the effectiveness of vaccine therapy plus sargramostim in treating ...

What is the current status of trial NCT00003959?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 1 participants. The study started on 1999-06.

What conditions does trial NCT00003959 study?

This clinical trial studies the following conditions: Leukemia, Myelodysplastic Syndromes.

What interventions are being tested in trial NCT00003959?

The interventions under investigation include: sargramostim (BIOLOGICAL), ras peptide cancer vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT00003959?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00003959 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Leukemia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00003959's enrollment target sits among peer trials

1 233rd of 233 the lowest of 233 other Leukemia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00003959, the US trial registry maintained by the National Library of Medicine. NCT00003959 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.