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ClinicalTrials.gov 51 recruiting now official registry

Leukemia clinical trials

51 of 274 indexed Leukemia trials are currently recruiting.

274 US clinical trials · 51 currently recruiting

Leukemia is the subject of 274 registered US clinical trials on ClinicalTrials.gov, 51 of them currently open to new participants. 19 are in Phase 3-4 (later-stage) and 193 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 37 of these trials.

The research picture

Leukemia has 274 registered US clinical trials, 51 of them open to new participants right now, about 19% of the total.

51
recruiting participants now
19%
of trials open to enrollment
19
in Phase 3–4 (later-stage)
37
top sponsor: M.D. Anderson Cancer Center
Phase 198Phase 295Phase 318Phase 41

Active & Recent Trials

274 total, page 3 of 6

COMPLETED NA 325 participants

Collection of Patient-Reported Symptoms and Performance Status Via the Internet

Alliance for Clinical Trials in Oncology

NCT00417040

COMPLETED Phase 1 282 participants

Clofarabine, Idarubicin, and Cytarabine (CIA) Versus Fludarabine, Idarubicin, and Cytarabine (FLAI) in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome

M.D. Anderson Cancer Center

NCT01289457

COMPLETED NA 279 participants

Illness Management and Parental Adjustment to Cancer Treatment

Children's Hospital Medical Center, Cincinnati

NCT02505165

COMPLETED Phase 2 277 participants

Everolimus in Treating Patients With Lymphoma That Has Relapsed or Not Responded to Previous Treatment

Mayo Clinic

NCT00436618

COMPLETED Phase 3 275 participants

Epoetin Alfa in Treating Anemia in Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma and Anemia Caused By Chemotherapy

Memorial Sloan Kettering Cancer Center

NCT00003341

COMPLETED Phase 2 264 participants

Efficacy Study of T Cell Depleted Allogeneic Non-myeloablative Stem Cell Transplant

David Rizzieri, MD

NCT00597714

COMPLETED Phase 3 254 participants

Chemotherapy in Treating Children With Down Syndrome and Myeloproliferative Disorder, Acute Myelogenous Leukemia, or Myelodysplastic Syndrome

Children's Oncology Group

NCT00003593

COMPLETED 252 participants

Validating Pain Scales in Children and Young Adults

National Cancer Institute (NCI)

NCT01639950

COMPLETED Phase 3 250 participants

Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer

University of South Florida

NCT00369564

COMPLETED Phase 3 233 participants

IV Busulfan With Allo-BMT: Study for Patients With Acute Myelogenous Leukemia and Myelodysplastic Syndrome

M.D. Anderson Cancer Center

NCT00469144

COMPLETED Phase 2 221 participants

Induction Intensification in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia

Children's Oncology Group

NCT00002756

COMPLETED Phase 3 198 participants

A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families

Tufts Medical Center

NCT00782145

COMPLETED Phase 2 185 participants

Phase II Decitabine (DAC) Versus Azacitidine (AZA) in Myelodysplastic Syndrome (MDS)

M.D. Anderson Cancer Center

NCT02269280

COMPLETED Phase 2 176 participants

Allo Non-Myeloablative SCT Utilizing Mis-Matched Family Member Stem Cells Purged Using Campath

David Rizzieri, MD

NCT00580034

COMPLETED Phase 2 156 participants

Radiation Therapy and Chemotherapy in Treating Children With CNS Relapse From Acute Lymphoblastic Leukemia

National Cancer Institute (NCI)

NCT00002704

COMPLETED Phase 2 130 participants

S0020 Immunosuppressive Therapy in Treating Patients With Myelodysplastic Syndrome

SWOG Cancer Research Network

NCT00016419

COMPLETED Phase 2 113 participants

Study of Voreloxin (Vosaroxin) in Older Patients With Untreated Acute Myeloid Leukemia

Sunesis Pharmaceuticals

NCT00607997

COMPLETED Phase 3 105 participants

S0521, Combination Chemotherapy With or Without Gemtuzumab Followed By Tretinoin, Mercaptopurine, and Methotrexate or Observation in Treating Patients With Acute Promyelocytic Leukemia

SWOG Cancer Research Network

NCT00492856

COMPLETED Phase 2 105 participants

Rituximab, Chemotherapy, and Filgrastim in Treating Patients With Burkitt's Lymphoma or Burkitt's Leukemia

Alliance for Clinical Trials in Oncology

NCT00039130

COMPLETED Phase 2 104 participants

Fludarabine and Monoclonal Antibody Therapy in Treating Patients With Untreated B-cell Chronic Lymphocytic Leukemia

Alliance for Clinical Trials in Oncology

NCT00003248

COMPLETED Early Phase 1 100 participants

Nutrition and Physical Activity Intervention in Preventing Excess Weight Gain in Pediatric Patients With Leukemia or Lymphoma Treated With Prednisone and/or Dexamethasone

M.D. Anderson Cancer Center

NCT05049785

COMPLETED Phase 2 100 participants

Topotecan in Treating Patients With Myelodysplastic Syndrome

Alliance for Clinical Trials in Oncology

NCT00003675

COMPLETED Phase 3 98 participants

Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain

Vanderbilt-Ingram Cancer Center

NCT00666211

COMPLETED Phase 2 96 participants

Phase II Trial of a Chemotherapy Alone Regimen of IV Busulfan (Busulfex), Melphalan and Fludarabine as Myeloablative Regimen Followed by an Allogeneic T-Cell Depleted Hematopoietic Stem Cell Transplant From an HLA-Identical, or HLA-Non Identical Related or Unrelated Donor

Memorial Sloan Kettering Cancer Center

NCT00582933

COMPLETED Phase 2 94 participants

Rituximab, Cyclophosphamide, and Pegfilgrastim in Treating Patients With Leukemia or Non-Hodgkin's Lymphoma

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT00278161

COMPLETED Phase 2 90 participants

Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases

Roswell Park Cancer Institute

NCT00003662

COMPLETED NA 90 participants

African American Cancer Clinical Trial Decisions: Testing Tailored Messages

Virginia Commonwealth University

NCT02356549

COMPLETED Phase 2 84 participants

Cord Blood With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cell Transplantation for Hematological Malignancies

Memorial Sloan Kettering Cancer Center

NCT01682226

COMPLETED Phase 3 83 participants

Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia

Children's Oncology Group

NCT00005977

COMPLETED Phase 2 82 participants

Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Cancer

Alliance for Clinical Trials in Oncology

NCT00053196

COMPLETED Phase 2 79 participants

S0333 Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

SWOG Cancer Research Network

NCT00109837

COMPLETED NA 78 participants

Improving Patient Education for Lymphoma and Leukemia Inpatients

Emory University

NCT02642510

COMPLETED Phase 1 70 participants

Safety and Efficacy of 90Y Zevalin in Nonmyeloablative Transplantation for Lymphoid Malignancies

M.D. Anderson Cancer Center

NCT00048737

COMPLETED 70 participants

C-Reactive Protein as a Predictor of Stem Cell Transplant Complications

Ann & Robert H Lurie Children's Hospital of Chicago

NCT00179868

COMPLETED Phase 2 69 participants

S0301 Cyclosporine, Daunorubicin, and Cytarabine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia

SWOG Cancer Research Network

NCT00066794

COMPLETED Phase 2 68 participants

Pentostatin, Cyclophosphamide, and Rituximab With or Without Bevacizumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Mayo Clinic

NCT00816595

COMPLETED Phase 2 68 participants

Donor Stem Cell Transplant in Treating Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Alliance for Clinical Trials in Oncology

NCT01027000

COMPLETED Phase 1 65 participants

Decitabine Followed by Clofarabine, Idarubicin, and Cytarabine in Acute Leukemia

M.D. Anderson Cancer Center

NCT01794702

COMPLETED NA 65 participants

Safety and Efficacy of Campath in Nonmyeloablative Transplantation

M.D. Anderson Cancer Center

NCT00038844

COMPLETED Phase 1 61 participants

Arsenic Trioxide, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Roswell Park Cancer Institute

NCT00093483

COMPLETED 61 participants

Evaluation of Loratadine for G-CSF Induced Bone Pain in Patients With Hematologic Malignancies

Wake Forest University Health Sciences

NCT02305979

COMPLETED Phase 2 60 participants

Thiotepa-Clofarabine-Busulfan With Allogeneic Stem Cell Transplant for High Risk Malignancies

M.D. Anderson Cancer Center

NCT00857389

COMPLETED Phase 2 59 participants

Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphocytic Leukemia

Children's Oncology Group

NCT00003671

COMPLETED NA 59 participants

A Novel Health Information Technology System (BMT Roadmap) for Pediatric BMT Patients and Caregivers

University of Michigan Rogel Cancer Center

NCT02409121

COMPLETED Phase 2 57 participants

Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED)

Merck Sharp & Dohme

NCT00086125

COMPLETED Phase 2 55 participants

CMA-676 in Treating Older Patients With Acute Myeloid Leukemia in First Relapse

Pfizer

NCT00003673

COMPLETED Phase 2 53 participants

Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant

Fred Hutchinson Cancer Center

NCT00410657

COMPLETED Phase 2 50 participants

Chemotherapy Plus Radiation Therapy and Biological Therapy in Treating Patients With Hematologic Cancer

Fred Hutchinson Cancer Center

NCT00002553

COMPLETED Phase 1 50 participants

Pentostatin, Cyclophosphamide, Rituximab, and Mitoxantrone in Treating Patients With Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Cancer

Memorial Sloan Kettering Cancer Center

NCT00546377

COMPLETED Phase 2 50 participants

SWOG-9400 Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Previously Untreated Acute Lymphocytic Leukemia

SWOG Cancer Research Network

NCT00002665

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Phase Distribution

PhaseTrial count
Phase 1 98
Phase 2 95
Phase 3 18
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Leukemia Trial Landscape

274 indexed Leukemia studies · 51 recruiting (19%).

Phase mix: 19 late (III/IV) vs 193 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (37 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Leukemia?

PlainTrial tracks 274 US clinical trials for Leukemia, of which 51 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.