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NCT00387608 · ClinicalTrials.gov registry record · Phase 1

ABT-888 in Patients With Refractory Solid Tumors or Hematologic Cancer

A Phase 1 study of Lymphoma and Leukemia, sponsored by National Institutes of Health Clinical Center (CC).

Completed
Registry status
Phase 1
Development phase
23
Enrollment target
1
Study location

NCT00387608 is a Phase 1 study of Lymphoma and Leukemia that has completed, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 23 participants, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00387608, a Phase 1 study of Lymphoma and Leukemia, has completed, sponsored by National Institutes of Health Clinical Center (CC).

COMPLETED
Registry status
Phase 1
Development phase
23 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: ABT-888 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Collecting and storing samples of blood from patients with cancer to study in the laboratory may help doctors learn more about the ways a patient's body handles the drug. PURPOSE: This early phase I trial is studying the side effects and best dose of ABT-888 in patients with refractory solid tumors or hematologic cancer.

Interventions

  • PROCEDURE biopsy
  • OTHER pharmacological study
  • DRUG veliparib

Study Locations (1)

Maryland

  • Warren Grant Magnuson Clinical Center - NCI Clinical Trials Referral Office - Bethesda

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2006-06
Est. Completion 2009-04
Phase Phase 1

What the Registry Record Tells You About NCT00387608

The ClinicalTrials.gov registry entry for NCT00387608 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (95% lower). The listed sponsor is National Institutes of Health Clinical Center (CC), which has 338 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Lymphoma appearing as the primary indexed condition, and to 3 interventions - of which biopsy is the first listed.

NCT00387608 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT00387608 about?

NCT00387608 is a clinical study titled "ABT-888 in Patients With Refractory Solid Tumors or Hematologic Cancer". RATIONALE: ABT-888 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Collecting and storing samples of blood from patients with cancer to study in the laboratory may help doctors learn more about the ways a patient's body handles the drug. PURPOSE: This ear...

What is the current status of trial NCT00387608?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2006-06. Estimated completion is 2009-04.

What conditions does trial NCT00387608 study?

This clinical trial studies the following conditions: Lymphoma, Leukemia, Unspecified Adult Solid Tumor, Protocol Specific.

What interventions are being tested in trial NCT00387608?

The interventions under investigation include: biopsy (PROCEDURE), pharmacological study (OTHER), veliparib (DRUG).

Who is sponsoring clinical trial NCT00387608?

This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00387608 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.