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NCT00840931 · ClinicalTrials.gov registry record · Phase 1

Immunotherapy Using Lenalidomide + Bystander Vaccine in High Risk Myelodysplastic Syndrome (MDS)

A Phase 1 study of Leukemia, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Completed
Registry status
Phase 1
Development phase
22
Enrollment target
1
Study location

NCT00840931 is a Phase 1 study of Leukemia that has completed, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 22 participants, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00840931, a Phase 1 study of Leukemia, has completed, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

COMPLETED
Registry status
Phase 1
Development phase
22 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to find out the maximum tolerated dose (MTD) of the combined therapy of lenalidomide (Revlimid®) and Granulocyte/macrophage colony stimulating factor and CD40 Ligand expressed in the K562 cell line (GM.CD40L) bystander vaccine. This research is also being done to see how well the combination of these drugs works to fight myelodysplastic syndrome (MDS).

Conditions Studied

Interventions

  • DRUG lenalidomide
  • BIOLOGICAL bystander vaccine

Study Locations (1)

Florida

  • H. Lee Moffitt Cancer Center & Research Institute - Tampa

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2009-02-02
Est. Completion 2019-12
Phase Phase 1

What the Registry Record Tells You About NCT00840931

The ClinicalTrials.gov registry entry for NCT00840931 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (95% lower). The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Leukemia appearing as the primary indexed condition, and to 2 interventions - of which lenalidomide is the first listed.

NCT00840931 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT00840931 about?

NCT00840931 is a clinical study titled "Immunotherapy Using Lenalidomide + Bystander Vaccine in High Risk Myelodysplastic Syndrome (MDS)". The purpose of this study is to find out the maximum tolerated dose (MTD) of the combined therapy of lenalidomide (Revlimid®) and Granulocyte/macrophage colony stimulating factor and CD40 Ligand expressed in the K562 cell line (GM.CD40L) bystander vaccine. This research is also being done to see how...

What is the current status of trial NCT00840931?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2009-02-02. Estimated completion is 2019-12.

What conditions does trial NCT00840931 study?

This clinical trial studies the following conditions: Leukemia.

What interventions are being tested in trial NCT00840931?

The interventions under investigation include: lenalidomide (DRUG), bystander vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT00840931?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00840931 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.