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NCT01541800 · ClinicalTrials.gov registry record

Circulating microRNAs as Disease Markers in Pediatric Cancers

A clinical trial of Lymphoma and Leukemia, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.

Completed
Registry status
20
Enrollment target
1
Study location

NCT01541800 is a study of Lymphoma and Leukemia that has completed, run by Ann & Robert H Lurie Children's Hospital of Chicago. The registered enrollment target is 20 participants, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01541800, a study of Lymphoma and Leukemia, has completed, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.

COMPLETED
Registry status
20 participants
Enrollment target
1
Study location

Study Summary

MicroRNAs are small molecules which have recently been discovered in cells. They are known to be responsible for the normal development of cells and when they are disrupted can contribute to the development of cancer. Many previous studies have been done evaluating the expression of microRNAs in normal tissues as well as a wide variety of cancers. Recently, microRNAs from tumor cells have been detected circulating in the blood of patients with cancer. This presents a novel opportunity to use microRNAs in the blood as an early predictor of cancer as well as a marker of response to therapy. No previous studies have been performed evaluating microRNAs in the blood or cerebrospinal fluid of patients with childhood cancers. We propose a feasibility study to evaluate the presence of microRNAs in the blood and cerebrospinal fluid of patients with central nervous system tumors, leukemia and lymphoma who are currently on chemotherapy and undergoing blood draws, lumbar punctures and/or reservoir taps for routine clinical care. If we're able to identify circulating microRNAs in this population of pediatric patients, we will build upon this data in proposing a future study.

Study Locations (1)

Illinois

  • Ann & Robert H. Lurie Children's Hospital of Chicago - Chicago

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2010-03
Est. Completion 2013-06

What the Registry Record Tells You About NCT01541800

The ClinicalTrials.gov registry entry for NCT01541800 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (96% lower). The listed sponsor is Ann & Robert H Lurie Children's Hospital of Chicago, which has 159 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Lymphoma appearing as the primary indexed condition, and to 0 interventions.

NCT01541800 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT01541800 about?

NCT01541800 is a clinical study titled "Circulating microRNAs as Disease Markers in Pediatric Cancers". MicroRNAs are small molecules which have recently been discovered in cells. They are known to be responsible for the normal development of cells and when they are disrupted can contribute to the development of cancer. Many previous studies have been done evaluating the expression of microRNAs in nor...

What is the current status of trial NCT01541800?

This trial is currently completed. The enrollment target is 20 participants. The study started on 2010-03. Estimated completion is 2013-06.

What conditions does trial NCT01541800 study?

This clinical trial studies the following conditions: Lymphoma, Leukemia, Central Nervous System.

Who is sponsoring clinical trial NCT01541800?

This trial is sponsored by Ann & Robert H Lurie Children's Hospital of Chicago, which has 159 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01541800 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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