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2026 data Public-data reference. official source

Infection

Open-data reference.

45 US clinical trials · 10 currently recruiting

Active & Recent Trials

RECRUITING NA 6,000 participants

Improving Implementation of Evidence-based Approaches and Surveillance to Prevent Bacterial Transmission and Infection

Trustees of Dartmouth College

NCT04600973

RECRUITING 4,200 participants

Biomarkers in Infection

Beth Israel Deaconess Medical Center

NCT02545478

RECRUITING NA 3,000 participants

Home Hospital for Suddenly Ill Adults

Brigham and Women's Hospital

NCT03524222

RECRUITING NA 2,000 participants

Microbial Cell-free Metagenomic Sequencing for Suspected Infections in Adult Immunocompromised Outpatients

Karius

NCT07110636

RECRUITING 400 participants

Diagnosis and Management of Inflammatory and Infectious Diseases

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00557726

RECRUITING 380 participants

Persona Revision Knee System Outcomes

Zimmer Biomet

NCT04821154

RECRUITING NA 300 participants

BLOOM: Pragmatic Feasibility Trial

Mayo Clinic

NCT07287332

RECRUITING 300 participants

Effect of Alcohol and Drugs of Abuse on Immune Function in Critically Ill Patients With Respiratory Failure

University of Colorado, Denver

NCT02299921

RECRUITING NA 30 participants

Copper Supplementation in Cirrhosis

University of Washington

NCT07471542

RECRUITING Phase 1 25 participants

NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)

National Institute of Allergy and Infectious Diseases (NIAID)

NCT05189925

COMPLETED 6,300 participants

Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study

National Eye Institute (NEI)

NCT00116090

COMPLETED 1,055 participants

Evaluation of the Heparin Binding Protein Levels in Sepsis

Christiana Care Health Services

NCT02533011

COMPLETED 815 participants

Early Identification of SEPsis SIGNs in Emergency Department

BioMérieux

NCT04261621

COMPLETED Phase 4 563 participants

Antibiotic Prophylaxis for Transrectal Prostate Biopsy

Northwestern University

NCT01659866

COMPLETED Phase 3 524 participants

Study of a Topical Gentamicin-Collagen Sponge Along With Systemic Antibiotic in Infected Diabetic Foot Ulcers

Innocoll

NCT02447172

COMPLETED 500 participants

A Retrospective Review of Infections Usually Observed in Transplant Recipients

University of Pittsburgh

NCT00298077

COMPLETED 477 participants

Evaluation of Infection in Obstructing Urolithiasis

University of Texas Southwestern Medical Center

NCT04332861

COMPLETED NA 400 participants

Timing of Antibiotic Prophylaxis for Cesarean Deliveries

University of Florida

NCT00805545

COMPLETED Phase 1 400 participants

Triple Dye Plus Alcohol Versus Triple Dye Alone for Newborn Umbilical Cord Care

Penn State University

NCT00127699

COMPLETED 350 participants

Retrospective Analysis of Clinical Features in Ventriculoperitoneal Shunt Infectionsin Adults

University of Pittsburgh

NCT00524108

COMPLETED NA 330 participants

Effects of a Cranberry Beverage on Women With Recent History of Urinary Tract Infections

Ocean Spray Cranberries

NCT01776021

COMPLETED Phase 4 265 participants

MAKE IT CLEAN, Impact of Pocket Revision on the Rate of Infection and Other Complications in Patients Requiring Pocket Manipulation for Generator Replacement and/or Lead Replacement or Revision: A Prospective Randomized Study

Dhanunjaya Lakkireddy, MD, FACC

NCT00599261

COMPLETED NA 172 participants

Remote Physician Care for Home Hospital Patients

Brigham and Women's Hospital

NCT04080570

COMPLETED 166 participants

Identification of Gene and Protein Markers of Kidney Injury in Aminoglycoside-treated Children

Virginia Commonwealth University

NCT00308906

COMPLETED 124 participants

Antibiotic Prophylaxis Before Percutaneous Gastrostomy

University of Washington

NCT01424085

COMPLETED Phase 3 114 participants

Safety and Effectiveness of Granulocyte Transfusions in Resolving Infection in People With Neutropenia (The RING Study)

Carelon Research

NCT00627393

COMPLETED 100 participants

Community - Associated Extended-spectrum Beta-lactamases (ESBL)

University of Pittsburgh

NCT00363220

COMPLETED NA 100 participants

Decreasing Infection In Arthroscopic Shoulder Surgery

McLaren Health Care

NCT02219776

COMPLETED 52 participants

Longitudinal Gene Expression Profiling in Adults After Traumatic Injury

Stanford University

NCT02656459

COMPLETED NA 45 participants

Clinical Experiment of Helicobacter Pylori Transmission

Stanford University

NCT00550368

COMPLETED NA 44 participants

CleanHands Sensor Based System to Improve Hand Hygiene and Reduce Infection

Microsensor Labs

NCT03948672

COMPLETED NA 40 participants

Bioequivalency Study of Clarithromycin Tablets Under Fasting Conditions

Roxane Laboratories

NCT00601315

COMPLETED Phase 2 40 participants

Study to Evaluate the Safety and Efficacy of Telavancin in the Treatment of Gram Positive Bloodstream Infections in Cancer Patients

M.D. Anderson Cancer Center

NCT01321879

COMPLETED Phase 2 32 participants

Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer

City of Hope Medical Center

NCT00589563

COMPLETED Phase 3 30 participants

Study of Antimicrobial Activity of Omiganan 1% Gel vs. Chlorhexidine 2% for Topical Skin Antisepsis in Healthy Adult Subjects

Cadence Pharmaceuticals

NCT00608959

COMPLETED Phase 1 24 participants

Pharmacokinetics and Safety of Cefazolin 2g in DUPLEX

B. Braun Medical

NCT01121354

COMPLETED 22 participants

Interactions of Environmental and Human Microbial Communities in a Pediatric Oncology Hospital

St. Jude Children's Research Hospital

NCT02948335

COMPLETED Phase 1 20 participants

Vancomycin Tissue Concentrations by Bier Block or Intravenous Administration

Mayo Clinic

NCT04673877

COMPLETED NA 16 participants

Community Central Line Infection Prevention Trial

Johns Hopkins University

NCT02351258

COMPLETED Phase 2 15 participants

Topical PluroGel PN for the Treatment of Mildly Infected Diabetic Foot Ulcers

PluroGen Therapeutics

NCT02119754

COMPLETED NA 7 participants

Rural Home Hospital: Proof of Concept

Brigham and Women's Hospital

NCT04531280

COMPLETED Early Phase 1 1 participants

Personalized Immunotherapeutic for Antibiotic-resistant Infection

Brigham and Women's Hospital

NCT02508584

COMPLETED NA

Vaccine Therapy in Preventing Flu in Children With Acute Lymphoblastic Leukemia

Roswell Park Cancer Institute

NCT00022035

COMPLETED Phase 1

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

National Institutes of Health Clinical Center (CC)

NCT00064311

COMPLETED Phase 1

Chemotherapy and Peripheral Stem Cell Transplantation Followed By Immunotherapy in Treating Patients With Multiple Myeloma

University of Maryland, Baltimore

NCT00046852

Phase Distribution

PhaseTrial count
Early Phase 1 7
Phase 2 3
Phase 3 3
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Infection Trial Landscape

ClinicalTrials.gov lists 45 US studies indexed under Infection, and 10 of those are currently open to recruitment — roughly 22% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Infection shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 10 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Infection is led by Brigham and Women's Hospital with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 45 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Infection?

PlainTrial tracks 45 US clinical trials for Infection, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Infection?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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