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NCT02533011 · ClinicalTrials.gov registry record
Evaluation of the Heparin Binding Protein Levels in Sepsis
A clinical trial of Sepsis and Infection, sponsored by Christiana Care Health Services.
- Completed
- Registry status
- 1,055
- Enrollment target
- 1
- Study location
NCT02533011: Completed study of Sepsis and Infection, sponsored by Christiana Care Health Services.
NCT02533011 is a study of Sepsis and Infection that has completed, run by Christiana Care Health Services. The registered enrollment target is 1,055 participants, below the 6,553-participant average among 90 other Sepsis trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02533011, a study of Sepsis and Infection, has completed, sponsored by Christiana Care Health Services.
- COMPLETED
- Registry status
- 1,055 participants
- Enrollment target
- 1
- Study location
Study Summary
Present criteria used to define sepsis are non-specific, making it difficult to both distinguish sepsis from other diseases and to predict which patients are likely to become more severely ill. In standard care, patients at risk of becoming more severely ill are neither identified nor indicated for resuscitative efforts until they develop hemodynamic insufficiency or organ failure; after progression to severe disease, mortality increases significantly. The identification of risk patients can lead to earlier initiation of resuscitation therapies and potentially lead to reduced morbidity and mortality. This study aims to determine whether Heparin-binding protein (HBP), which is secreted from neutrophils during infection and a mediator of vascular leakage, can act as a biomarker for the progression to severe sepsis with circulatory failure. The objective of this study is to validate the utility of HBP to predict the development of delayed onset organ dysfunction in sepsis in patients and to compare the performance of HBP relative to currently used prognostic biomarkers in sepsis.
Primary Outcome
Patients with septic shock or severe sepsis
Conditions Studied
Interventions
- OTHER HBP lab test
Study Locations (1)
Delaware
- Christiana Care Health System - Newark
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,055 participants |
| Start Date | 2015-07 |
| Est. Completion | 2017-07 |
What the finished NCT02533011 record still lists
NCT02533011 is an observational study that tracks outcomes without assigning an intervention. Its 1,055 participants enrollment target places it among the larger protocols in the corpus, below the 6,553-participant average among 90 other Sepsis trials with a reported enrollment target (84% lower).
The record links to 3 conditions, with Sepsis appearing as the primary indexed condition, and to 1 intervention - of which HBP lab test is the first listed.
NCT02533011 reports a single indexed study location in Delaware.
Frequently Asked Questions
What is clinical trial NCT02533011 about?
NCT02533011 is a clinical study titled "Evaluation of the Heparin Binding Protein Levels in Sepsis". Present criteria used to define sepsis are non-specific, making it difficult to both distinguish sepsis from other diseases and to predict which patients are likely to become more severely ill. In standard care, patients at risk of becoming more severely ill are neither identified nor indicated for ...
What is the current status of trial NCT02533011?
This trial is currently completed. The enrollment target is 1,055 participants. The study started on 2015-07. Estimated completion is 2017-07.
What conditions does trial NCT02533011 study?
This clinical trial studies the following conditions: Sepsis, Infection, Septic Shock.
What interventions are being tested in trial NCT02533011?
The interventions under investigation include: HBP lab test (OTHER).
Who is sponsoring clinical trial NCT02533011?
This trial is sponsored by Christiana Care Health Services, which has 82 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02533011 being conducted?
This trial has 1 study location across Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sepsis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02533011's enrollment target sits among peer trials
1,055 18th of 90 higher than 73 of 90 other Sepsis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sepsis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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